Annotation Detail for CPLX2

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Basic Information Top

Gene Symbol:	CPLX2 ( 921-L,CPX-2,CPX2,Hfb1,MGC138492 )
Gene Full Name:	complexin 2
Band:	5q35.2
Quick Links	Entrez ID:10814; OMIM: 605033; Uniprot ID:CPLX2_HUMAN; ENSEMBL ID: ENSG00000145920; HGNC ID: 2310
Relate to Another Database:	SFARIGene; denovo-db

Pathways, Diseases and Drugs

TF binding site

Post Translation Modification

PTM Sites from Uniprot:2 results
Experimental PTM Sites from dbPTM:1 results
Predicted PTM Sites by profile HMM from dbPTM:2 results

Location(AA)	Modification
14	N6-acetyllysine.
93	Phosphoserine (By similarity).

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

RefSeq ID: NM_001008220
Location:chr5 175231106-175243628
strand:+

Upstream the gene:0 results
Downstream the gene:9 results
Inside the gene:14 results

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	G2	GSE9613	175243852	175244126	274	361
CTCF	G2	GSE9613	175246605	175246887	282	3118
CTCF	G2	GSE9613	175249728	175250131	403	6301
CTCF	G2	GSE9613	175253667	175253990	323	10200
CTCF	G2	GSE9613	175255512	175255740	228	11998
CTCF	G2	GSE9613	175259260	175259452	192	15728
NRSF	mAb	Jurkat	175244643	175245261	618	1324
NRSF	mAb	Jurkat	175246324	175246887	563	2977
TFAP2C	MCF7	GSE21234	175254993	175255769	776	11753

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	G2	GSE9613	175231306	175231947	641	0
CTCF	G2	GSE9613	175234414	175234666	252	0
CTCF	G2	GSE9613	175238153	175238779	626	0
CTCF	G2	GSE9613	175239876	175240183	307	0
CTCF	G2	GSE9613	175241896	175242945	1049	0
Gata2	K562	GSE18868	175238477	175239008	531	0
H3K27me3	colorectal	cancer	175233621	175235556	1935	0
NRSF	Jurkat	GSE13047	175231017	175233461	2444	0
NRSF	mAb	Jurkat	175232741	175236891	4150	0
NRSF	mAb	Jurkat	175240777	175241145	368	0
NRSF-mono	Jurkat	QuESTdata	175231022	175232312	1290	0
NRSF	pAb	Jurkat	175232841	175235863	3022	0
NRSF-poly	Jurkat	QuESTdata	175231087	175232380	1293	0
hScc1	Bcell	GSE12603	175231739	175231947	208	0

Validated miRNA targets

miR Walk:1 results
Tarbase V5.0:0 results

Micro RNA Name	Stem Loop Name	The chromosome that miRNA located	Publication
hsa-miR-498	hsa-mir-498	19	20819981

Cis-Nats regulation

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

Studies: 1,036
Genes: 1,379
CNVs/SVs: 5,420
SNVs/Indels: 11,669
de novo Mutations: 5,669
Mosaics: 789
Linkage Regions: 172

Paper Collected: 6/30/2018

Last Update: 8/26/2018

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