AutismKB 2.0

Annotation Detail for SRCAP


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Basic Information Top
Gene Symbol:SRCAP ( DOMO1,EAF1,FLJ44499,KIAA0309,SWR1 )
Gene Full Name: Snf2-related CREBBP activator protein
Band: 16p11.2
Quick LinksEntrez ID:10847; OMIM: 611421; Uniprot ID:SRCAP_HUMAN; ENSEMBL ID: ENSG00000080603; HGNC ID: 16974
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
248Phosphoserine.
258Phosphoserine.
274Phosphoserine.
562Phosphoserine.
568Phosphoserine.
572Phosphothreonine.
2258Phosphothreonine.
2425Phosphothreonine.
2430Phosphoserine.
2787Phosphoserine.
2790Phosphoserine.
2869Phosphoserine.
3148Phosphoserine.
3161Phosphoserine.
3168Phosphoserine.
3172Phosphoserine.
3177Phosphoserine.
Location(AA) Modifications Resource
No data
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_006662
  • Location:chr16 30626079-30658553
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 30612811 30613051 240 13149
CTCF CD4SISSRdata 30612811 30613051 240 13149
CTCF JurkatGSE12889 30612757 30613047 290 13178
CTCF G2GSE9613 30612763 30613013 250 13192
ETS1 JurkatGSE17954 30616333 30618606 2273 8610
GABP k562GSE8489 30617792 30619160 1368 7604
H3ac HepG2E 30616295 30616855 560 9505
H3ac HepG2E 30617792 30619323 1531 7522
Nanog ESGSE20650 30611043 30611745 702 14686
Nanog hESGSE18292 30611338 30611609 271 14606
Oct1 HelaGSE14283 30619529 30619562 33 6534
Oct4 hESGSE21916 30611049 30611784 735 14663
PHF8 293TGSE20725 30616393 30618681 2288 8543
PHF8 HeLaGSE20725 30616382 30618329 1947 8724
PHF8 Hs68minusFBSGSE20725 30616483 30617698 1215 8989
PHF8 Hs68plusFBSGSE20725 30616627 30618628 2001 8452
Rb GrowingGSE19898 30617509 30617703 194 8474
Rb GrowingGSE19898 30618101 30618305 204 7877
Rb QuiescentGSE19898 30617102 30617382 280 8838
Rb QuiescentGSE19898 30617435 30617889 454 8418
Rb QuiescentGSE19898 30617945 30618341 396 7937
Rb SenescentGSE19898 30617201 30617850 649 8554
Rb shRbSenescenceGSE19898 30617565 30617864 299 8365
hScc1 BcellGSE12603 30612665 30613013 348 13241
hScc1 CdLSGSE12603 30612347 30613013 666 13400
p130 QuiescentGSE19898 30616724 30617366 642 9035
p130 QuiescentGSE19898 30617460 30618277 817 8211
p130 SenescentGSE19898 30616812 30617430 618 8959
p130 SenescentGSE19898 30617611 30618242 631 8153
p130 shRbQuiescentGSE19898 30616672 30617392 720 9048
p130 shRbSenescentGSE19898 30616749 30618266 1517 8572
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 30640029 30640319 290 0
Oct1 HelaGSE14283 30643519 30643552 33 0
hScc1 BcellGSE12603 30638968 30639119 151 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018