AutismKB 2.0

Annotation Detail for ME3


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Basic Information Top
Gene Symbol:ME3 ( FLJ34862 )
Gene Full Name: malic enzyme 3, NADP(+)-dependent, mitochondrial
Band: 11q14.2
Quick LinksEntrez ID:10873; OMIM: 604626; Uniprot ID:MAON_HUMAN; ENSEMBL ID: ENSG00000151376; HGNC ID: 6985
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
151Phosphothreonine(PKC)HMM predict
398Phosphoserine(CK1)HMM predict
443N-linkedHMM predict
446Phosphoserine(IKK)HMM predict
469Phosphoserine(CDC2)HMM predict
530Phosphoserine(ATM)HMM predict
540Phosphothreonine(PKC)HMM predict
564SulfotyrosineHMM predict
584SulfotyrosineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001014811
  • Location:chr11 85829799-86060887
  • strand:-
No data
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T30-glioblastomaGSE21026 85912143 85913922 1779 0
CTCF CD4GSE12889 85844869 85845092 223 0
CTCF CD4SISSRdata 85844869 85845092 223 0
CTCF JurkatGSE12889 85844809 85845091 282 0
ER E2-MCF7GSE14664 85894076 85894155 79 0
ER E2-MCF7GSE14664 85901770 85901802 32 0
ER E2-MCF7GSE14664 85901850 85901940 90 0
ER E2-MCF7GSE14664 86009845 86009933 88 0
ER E2-MCF7GSE14664 86031336 86031373 37 0
ER E2-MCF7GSE14664 86031751 86031848 97 0
ER E2-MCF7GSE14664 86045392 86045480 88 0
ER E2-MCF7GSE14664 86050918 86050965 47 0
ER E2-MCF7GSE14664 86060627 86060663 36 0
ER Fulvestrant-MCF7GSE14664 85844498 85844555 57 0
ER Fulvestrant-MCF7GSE14664 85901655 85901732 77 0
ER Fulvestrant-MCF7GSE14664 85901769 85901802 33 0
ER Fulvestrant-MCF7GSE14664 85901850 85901938 88 0
ER Fulvestrant-MCF7GSE14664 85917516 85917618 102 0
ER Fulvestrant-MCF7GSE14664 85964621 85964698 77 0
ER Fulvestrant-MCF7GSE14664 85972181 85972228 47 0
ER Fulvestrant-MCF7GSE14664 86014089 86014151 62 0
ER Fulvestrant-MCF7GSE14664 86019612 86019652 40 0
ER Fulvestrant-MCF7GSE14664 86029173 86029229 56 0
ER Fulvestrant-MCF7GSE14664 86041283 86041338 55 0
ER Fulvestrant-MCF7GSE14664 86054449 86054518 69 0
ER Fulvestrant-MCF7GSE14664 86060617 86060659 42 0
ER MCF7GSE19013 85888081 85889108 1027 0
ER MCF7GSE10800 86060201 86060545 344 0
FOXA1 DLD1GSE12801 85858625 85859325 700 0
FOXA1 DLD1GSE12801 85912608 85913397 789 0
FOXA1 DLD1GSE12801 85940018 85940770 752 0
FOXA1 DLD1GSE12801 85971501 85972172 671 0
FOXA1 DLD1GSE12801 85981053 85981760 707 0
FOXA1 MCF7GSE15244 85858665 85858960 295 0
FOXA1 MCF7GSE15244 85875318 85876047 729 0
FOXA1 MCF7GSE15244 85888017 85889023 1006 0
FOXA1 MCF7GSE15244 85912458 85913756 1298 0
FOXA1 MCF7GSE15244 85940053 85940770 717 0
Fos K562GSE19551 85912733 85913326 593 0
Fos K562GSE19551 85981395 85982071 676 0
FoxA1 MCF7MACSdata 85912738 85913159 421 0
GATA3 MCF7GSE15244 85887858 85889423 1565 0
GATA3 MCF7GSE15244 85907810 85908482 672 0
GATA3 MCF7GSE15244 86055515 86056312 797 0
GATA3 MCF7GSE15244 86059498 86059757 259 0
Myc K562GSE19551 85981594 85981935 341 0
Nanog hESGSE18292 85866946 85867332 386 0
Nanog hESGSE18292 85885202 85885566 364 0
Oct1 H2O2-HelaGSE14283 85981931 85981958 27 0
Oct1 H2O2-HelaGSE14283 85989299 85989327 28 0
Oct1 H2O2-HelaGSE14283 85998107 85998134 27 0
Oct1 H2O2-HelaGSE14283 86039165 86039199 34 0
Oct1 HelaGSE14283 85848121 85848158 37 0
Oct1 HelaGSE14283 85860680 85860711 31 0
Oct1 HelaGSE14283 85863315 85863376 61 0
Oct1 HelaGSE14283 85879107 85879142 35 0
Oct1 HelaGSE14283 85913360 85913387 27 0
Oct1 HelaGSE14283 85946276 85946340 64 0
Oct1 HelaGSE14283 85969166 85969234 68 0
Oct1 HelaGSE14283 85989298 85989327 29 0
Oct1 HelaGSE14283 86012651 86012688 37 0
Oct1 HelaGSE14283 86034868 86034910 42 0
Oct1 HelaGSE14283 86037206 86037240 34 0
Oct1 HelaGSE14283 86039165 86039199 34 0
Oct1 HelaGSE14283 86053013 86053089 76 0
Oct4 hESGSE17917 85999317 85999506 189 0
P300 T0-glioblastomaGSE21026 85912372 85913573 1201 0
P300 T30-glioblastomaGSE21026 85912437 85913896 1459 0
P300 T30-glioblastomaGSE21026 86021073 86022656 1583 0
RARA MCF7GSE15244 85848209 85848702 493 0
RARA MCF7GSE15244 85858376 85859165 789 0
RARA MCF7GSE15244 85887858 85889247 1389 0
RARA MCF7GSE15244 85907810 85908556 746 0
RARA MCF7GSE15244 85912351 85913756 1405 0
RARA MCF7GSE15244 85940018 85940770 752 0
RARA MCF7GSE15244 85960525 85960935 410 0
RARA MCF7GSE15244 85981084 85982204 1120 0
RARA MCF7GSE15244 86021433 86021904 471 0
RARG MCF7GSE15244 85858625 85859806 1181 0
RARG MCF7GSE15244 85866823 85867206 383 0
RARG MCF7GSE15244 85887858 85889173 1315 0
RARG MCF7GSE15244 85907810 85908420 610 0
RARG MCF7GSE15244 85912458 85913756 1298 0
RARG MCF7GSE15244 85940018 85940770 752 0
RARG MCF7GSE15244 85966701 85967286 585 0
RARG MCF7GSE15244 86021433 86022187 754 0
RNAII Tamoxifen-MCF7GSE14664 85964655 85964732 77 0
RUNX JurkatGSE17954 86026847 86027064 217 0
Rb GrowingGSE19898 85848882 85849098 216 0
Rb GrowingGSE19898 85862754 85862963 209 0
Rb QuiescentGSE19898 85872628 85872884 256 0
Rb QuiescentGSE19898 85873093 85873347 254 0
Rb SenescentGSE19898 85872556 85873343 787 0
STAT1 HeLaGSE12782 85830193 85832562 2369 0
STAT1 HeLaGSE12783 85830227 85832528 2301 0
STAT1 HeLaGSE12783 85994686 85996174 1488 0
STAT1 IFNSISSRdata 85830097 85832119 2022 0
TAF HelaGSE8489 85855928 85856102 174 0
TFAP2C MCF7GSE21234 85997028 85997546 518 0
USF1 HepG2E 85887686 85888257 571 0
VDR GM10855-stimGSE22484 85834772 85836354 1582 0
VDR GM10861-stimGSE22484 85834413 85836247 1834 0
hScc1 BcellGSE12603 85844466 85845353 887 0
hScc1 BcellGSE12603 85886671 85886896 225 0
hScc1 BcellGSE12603 86060509 86060973 464 0
hScc1 CdLSGSE12603 85844433 85845455 1022 0
hScc1 CdLSGSE12603 85996620 85997471 851 0
hScc1 G2GSE9613 85844537 85845455 918 0
hScc1 G2GSE9613 85996871 85997471 600 0
hScc1 G2GSE9613 86060201 86061009 808 0
p130 QuiescentGSE19898 85872793 85873233 440 0
p63 keratinocytesGSE17611 85912669 85913921 1252 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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