AutismKB 2.0

Annotation Detail for PRSS21


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Basic Information Top
Gene Symbol:PRSS21 ( ESP-1,ESP1,TEST1,TESTISIN )
Gene Full Name: protease, serine, 21 (testisin)
Band: 16p13.3
Quick LinksEntrez ID:10942; OMIM: 608159; Uniprot ID:TEST_HUMAN; ENSEMBL ID: ENSG00000007038; HGNC ID: 9485
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
167N-linked (GlcNAc...) (Potential).
200N-linked (GlcNAc...) (Potential).
273N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
167N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
200N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
273N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
288GPI-anchor amidated serine (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
23Phosphoserine(ATM)HMM predict
167N-linkedHMM predict
178Phosphotyrosine(INSR)HMM predict
200N-linkedHMM predict
201N-linkedHMM predict
205N-linkedHMM predict
291Phosphoserine(ATM)HMM predict
311LeucineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_006799
  • Location:chr16 2807164-2811716
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 2805380 2805634 254 1658
hScc1 BcellGSE12603 2805290 2805634 344 1703
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 2810802 2811363 561 0
Myc K562GSE19551 2806901 2808049 1148 0
Oct4 hESGSE17917 2807178 2807440 262 0
Rb GrowingGSE19898 2811100 2811300 200 0
hScc1 BcellGSE12603 2810601 2811326 725 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-let-7b hsa-let-7b 22 18668040
hsa-let-7b* hsa-let-7b 22 18668040
hsa-miR-1 hsa-mir-1-2 18 18668040
hsa-miR-1 hsa-mir-1-1 20 18668040
hsa-miR-155 hsa-mir-155 21 18668040
hsa-miR-155* hsa-mir-155 21 18668040
hsa-miR-16 hsa-mir-16-1 13 18668040
hsa-miR-16 hsa-mir-16-2 3 18668040
hsa-miR-30a hsa-mir-30a 6 18668040
hsa-miR-30a* hsa-mir-30a 6 18668040
hsa-miR-30b hsa-mir-30b 8 18668040
hsa-miR-30b* hsa-mir-30b 8 18668040
hsa-miR-30c hsa-mir-30c-2 6 18668040
hsa-miR-30c hsa-mir-30c-1 1 18668040
hsa-miR-30c-1* hsa-mir-30c-1 1 18668040
hsa-miR-30c-2* hsa-mir-30c-2 6 18668040
hsa-miR-30d hsa-mir-30d 8 18668040
hsa-miR-30d* hsa-mir-30d 8 18668040
hsa-miR-30e hsa-mir-30e 1 18668040
hsa-miR-30e* hsa-mir-30e 1 18668040
ID in Tarbase Data Type Support Type miRNA Gene Direct Support Publication
1184 Unknown pSILAC miR-1 PRSS21 down 75-50% 18668040
Ensembl Protein Type Differentially expressed in Pathology or Event Mis Regulation Gene Expression Tumour Involvement
ENSG00000007038 n_a n_a n_a leukocyte "malignant tumour, carcinoma"
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018