AutismKB 2.0

Annotation Detail for TMED2


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Basic Information Top
Gene Symbol:TMED2 ( FLJ21323,P24A,RNP24 )
Gene Full Name: transmembrane emp24 domain trafficking protein 2
Band: 12q24.31
Quick LinksEntrez ID:10959; OMIM: NA; Uniprot ID:TMED2_HUMAN; ENSEMBL ID: ENSG00000086598; HGNC ID: 16996
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
150Phosphotyrosine(EGFR)HMM predict
150Phosphotyrosine(SRC)HMM predict
150Phosphotyrosine(Syk)HMM predict
190Phosphotyrosine(Jak)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_006815
  • Location:chr12 122635028-122648633
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 122632674 122632975 301 2204
CTCF CD4SISSRdata 122632674 122632975 301 2204
CTCF G2GSE9613 122632806 122633326 520 1963
CTCF G2GSE9613 122634714 122635103 389 120
H3ac HepG2E 122632806 122633326 520 1963
P300 T0-glioblastomaGSE21026 122634408 122635138 730 256
P300 T30-glioblastomaGSE21026 122634364 122635521 1157 86
PHF8 HeLaGSE20725 122634443 122635565 1122 25
PHF8 Hs68plusFBSGSE20725 122633725 122635824 2099 254
RARA MCF7GSE15244 122632806 122633326 520 1963
RARG MCF7GSE15244 122632806 122633326 520 1963
Rb GrowingGSE19898 122632701 122632969 268 2194
Rb QuiescentGSE19898 122632620 122632906 286 2266
Rb QuiescentGSE19898 122634724 122635036 312 149
Rb SenescentGSE19898 122632628 122632988 360 2221
Rb SenescentGSE19898 122634626 122635060 434 186
Rb shRbSenescenceGSE19898 122632718 122632831 113 2254
Rb shRbSenescenceGSE19898 122634900 122635072 172 43
Sox2 hESGSE18292 122632743 122632922 179 2196
TAF HelaGSE8489 122634714 122634916 202 214
hScc1 BcellGSE12603 122632806 122633297 491 1977
hScc1 BcellGSE12603 122634714 122635013 299 165
hScc1 CdLSGSE12603 122632806 122633326 520 1963
hScc1 G2GSE9613 122632806 122633297 491 1977
p130 QuiescentGSE19898 122632655 122632858 203 2272
p130 QuiescentGSE19898 122634767 122635033 266 129
p130 SenescentGSE19898 122632625 122632876 251 2278
p130 SenescentGSE19898 122634648 122635245 597 82
p130 shRbQuiescentGSE19898 122634670 122635117 447 135
p130 shRbSenescentGSE19898 122632667 122632878 211 2256
p130 shRbSenescentGSE19898 122634690 122635053 363 157
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
GABP k562GSE8489 122649783 122650111 328 1314
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ETS1 JurkatGSE17954 122634427 122635771 1344 0
H3K4me2 HCT116GSE10453 122635795 122636213 418 0
H3K4me3 colorectalcancer 122635678 122636213 535 0
H3ac HepG2E 122635608 122636213 605 0
Rb shRbSenescenceGSE19898 122635111 122635466 355 0
TAF HelaGSE8489 122637157 122637580 423 0
p130 shRbQuiescentGSE19898 122635191 122635704 513 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-let-7b hsa-let-7b 22 18668040
hsa-let-7b* hsa-let-7b 22 18668040
hsa-miR-1 hsa-mir-1-2 18 18668040
hsa-miR-1 hsa-mir-1-1 20 18668040
hsa-miR-155 hsa-mir-155 21 18668040
hsa-miR-155* hsa-mir-155 21 18668040
hsa-miR-16 hsa-mir-16-1 13 18668040
hsa-miR-16 hsa-mir-16-2 3 18668040
hsa-miR-30a hsa-mir-30a 6 18668040
hsa-miR-30a* hsa-mir-30a 6 18668040
hsa-miR-30b hsa-mir-30b 8 18668040
hsa-miR-30b* hsa-mir-30b 8 18668040
hsa-miR-30c hsa-mir-30c-2 6 18668040
hsa-miR-30c hsa-mir-30c-1 1 18668040
hsa-miR-30c-1* hsa-mir-30c-1 1 18668040
hsa-miR-30c-2* hsa-mir-30c-2 6 18668040
hsa-miR-30d hsa-mir-30d 8 18668040
hsa-miR-30d* hsa-mir-30d 8 18668040
hsa-miR-30e hsa-mir-30e 1 18668040
hsa-miR-30e* hsa-mir-30e 1 18668040
ID in Tarbase Data Type Support Type miRNA Gene Direct Support Publication
1291 Unknown pSILAC miR-30 TMED2 down 50-25% 18668040
Ensembl Protein Type Differentially expressed in Pathology or Event Mis Regulation Gene Expression Tumour Involvement
ENSG00000086598 n_a n_a n_a "epithelium, squamous cell, lymphocyte, muscle cell" "benign tumour, malignant tumour, carcinoma, leukaemia, non-Hodgkin's, sarcoma"
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
6764 mRNA RNP24 chr12 122594040 122607561 287 EST chr12 122607274 122608009Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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