AutismKB 2.0

Annotation Detail for FERMT2


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Basic Information Top
Gene Symbol:FERMT2 ( DKFZp686G11125,FLJ34213,FLJ44462,KIND2,MIG2,PLEKHC1,UNC112,UNC112B,mig-2 )
Gene Full Name: fermitin family member 2
Band: 14q22.1
Quick LinksEntrez ID:10979; OMIM: 607746; Uniprot ID:FERM2_HUMAN; ENSEMBL ID: ENSG00000073712; HGNC ID: 15767
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
159Phosphoserine.
181Phosphoserine.
666Phosphoserine.
Location(AA) Modifications Resource
No data
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_006832
  • Location:chr14 52393742-52487459
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 52497702 52497872 170 10328
CTCF CD4SISSRdata 52497702 52497872 170 10328
CTCF HelaGSE12889 52497662 52497822 160 10283
CTCF G2GSE9613 52487968 52488327 359 688
CTCF G2GSE9613 52497603 52497833 230 10259
H3K27me3 colorectalcancer 52488293 52490211 1918 1793
PHF8 HeLaGSE20725 52486766 52488523 1757 185
RARA MCF7GSE15244 52497061 52497833 772 9988
Rb QuiescentGSE19898 52488447 52488688 241 1108
TFAP2C MCF7GSE21234 52487817 52488805 988 852
hScc1 BcellGSE12603 52487368 52487832 464 141
hScc1 BcellGSE12603 52497425 52497833 408 10170
hScc1 CdLSGSE12603 52487155 52488118 963 177
hScc1 CdLSGSE12603 52497232 52497833 601 10073
p130 QuiescentGSE19898 52488546 52488772 226 1200
p130 shRbQuiescentGSE19898 52488037 52488556 519 837
p130 shRbSenescentGSE19898 52487433 52487751 318 133
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T0-glioblastomaGSE21026 52382380 52382939 559 11083
Nanog hESGSE18292 52380735 52381249 514 12751
RARG MCF7GSE15244 52390064 52390352 288 3535
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER Fulvestrant-MCF7GSE14664 52477211 52477255 44 0
ER Fulvestrant-MCF7GSE14664 52480483 52480516 33 0
FoxA1 MCF7MACSdata 52471316 52471539 223 0
H3K27me3 colorectalcancer 52485929 52487226 1297 0
H3K4me2 HCT116GSE10453 52486210 52486719 509 0
H3K4me3 colorectalcancer 52486210 52487368 1158 0
H3ac HepG2E 52485463 52486897 1434 0
Nanog hESGSE18292 52409726 52409983 257 0
Oct1 HelaGSE14283 52421156 52421189 33 0
Oct1 HelaGSE14283 52480483 52480517 34 0
PHF8 Hs68minusFBSGSE20725 52486554 52487561 1007 0
RARA MCF7GSE15244 52456476 52456730 254 0
RARG MCF7GSE15244 52456539 52456730 191 0
RARG MCF7GSE15244 52486281 52486755 474 0
TAF HelaGSE8489 52486002 52486827 825 0
TFAP2C MCF7GSE21234 52437067 52437660 593 0
TFAP2C MCF7GSE21234 52454113 52454654 541 0
hScc1 CdLSGSE12603 52460418 52460748 330 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-let-7b hsa-let-7b 22 18668040
hsa-let-7b* hsa-let-7b 22 18668040
hsa-miR-1 hsa-mir-1-2 18 18668040
hsa-miR-1 hsa-mir-1-1 20 18668040
hsa-miR-155 hsa-mir-155 21 18668040
hsa-miR-155* hsa-mir-155 21 18668040
hsa-miR-16 hsa-mir-16-1 13 18668040
hsa-miR-16 hsa-mir-16-2 3 18668040
hsa-miR-30a hsa-mir-30a 6 18668040
hsa-miR-30a* hsa-mir-30a 6 18668040
hsa-miR-30b hsa-mir-30b 8 18668040
hsa-miR-30b* hsa-mir-30b 8 18668040
hsa-miR-30c hsa-mir-30c-2 6 18668040
hsa-miR-30c hsa-mir-30c-1 1 18668040
hsa-miR-30c-1* hsa-mir-30c-1 1 18668040
hsa-miR-30c-2* hsa-mir-30c-2 6 18668040
hsa-miR-30d hsa-mir-30d 8 18668040
hsa-miR-30d* hsa-mir-30d 8 18668040
hsa-miR-30e hsa-mir-30e 1 18668040
hsa-miR-30e* hsa-mir-30e 1 18668040
ID in Tarbase Data Type Support Type miRNA Gene Direct Support Publication
1180 Unknown pSILAC miR-1 PLEKHC1 down 50-25% 18668040
Ensembl Protein Type Differentially expressed in Pathology or Event Mis Regulation Gene Expression Tumour Involvement
ENSG00000073712 n_a n_a n_a "epithelium, lymphocyte" "benign tumour, malignant tumour, carcinoma, sarcoma"
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018