AutismKB 2.0

Annotation Detail for MAPRE2


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Basic Information Top
Gene Symbol:MAPRE2 ( EB1,EB2,RP1 )
Gene Full Name: microtubule-associated protein, RP/EB family, member 2
Band: 18q12.1-q12.2
Quick LinksEntrez ID:10982; OMIM: 605789; Uniprot ID:MARE2_HUMAN; ENSEMBL ID: ENSG00000166974; HGNC ID: 6891
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
9Phosphoserine.
167Phosphotyrosine.
200Phosphoserine.
208Phosphoserine.
219Phosphoserine.
223Phosphoserine.
271N6-acetyllysine.
Location(AA) Modifications Resource
167Phosphotyrosine.Swiss-Prot 53.0
167PhosphotyrosinePhospho.ELM 6.0
200Phosphoserine.Swiss-Prot 53.0
200PhosphoserinePhospho.ELM 6.0
Location(AA) Modification Resource
9Phosphoserine(CDK)HMM predict
9Phosphoserine(CDC2)HMM predict
23N-linkedHMM predict
33Phosphothreonine(PKA)HMM predict
41Phosphoserine(CAMK2)HMM predict
74N-linkedHMM predict
98S-palmitoylHMM predict
162SulfotyrosineHMM predict
167Phosphotyrosine(Jak)HMM predict
167Phosphotyrosine(INSR)HMM predict
167Phosphotyrosine(Syk)HMM predict
208O-linkedHMM predict
217Phosphothreonine(CDK)HMM predict
217Phosphothreonine(MAPK)HMM predict
217Phosphothreonine(CDC2)HMM predict
219O-linkedHMM predict
222Phosphoserine(CDC2)HMM predict
229Phosphoserine(PKA)HMM predict
230Phosphoserine(IKK)HMM predict
230O-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_014268
  • Location:chr18 30875388-30975812
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 30860443 30860805 362 14765
CTCF CD4SISSRdata 30860443 30860805 362 14765
USF1 HepG2E 30873155 30873865 710 1879
p130 QuiescentGSE19898 30874890 30875282 392 303
p130 shRbQuiescentGSE19898 30874686 30875232 546 430
p130 shRbSenescentGSE19898 30874804 30875842 1038 66
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 30978048 30978200 152 2312
CTCF CD4SISSRdata 30978048 30978200 152 2312
CTCF G2GSE9613 30977885 30978176 291 2218
TFAP2C MCF7GSE21234 30977985 30978345 360 2353
hScc1 BcellGSE12603 30977785 30978250 465 2205
hScc1 CdLSGSE12603 30977630 30978439 809 2222
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP JurkatGSE17954 30874351 30876992 2641 0
CTCF G2GSE9613 30875216 30875717 501 0
H3K4me3 colorectalcancer 30875396 30876273 877 0
H3ac HepG2E 30875863 30876525 662 0
Oct1 H2O2-HelaGSE14283 30917019 30917045 26 0
PHF8 HeLaGSE20725 30874984 30875890 906 0
Rb QuiescentGSE19898 30875277 30875802 525 0
Rb SenescentGSE19898 30875277 30875755 478 0
Rb shRbSenescenceGSE19898 30875289 30875587 298 0
USF1 HepG2E 30874526 30877158 2632 0
USF2 HepG2E 30874763 30876558 1795 0
hScc1 BcellGSE12603 30875216 30875717 501 0
hScc1 BcellGSE12603 30962727 30963006 279 0
p130 SenescentGSE19898 30875340 30875531 191 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018