Annotation Detail for SF3B2
Basic Information Top
| Gene Symbol: | SF3B2 ( Cus1,SAP145,SF3B145,SF3b1,SF3b150 ) |
|---|---|
| Gene Full Name: | splicing factor 3b, subunit 2, 145kDa |
| Band: | 11q13.1 |
| Quick Links | Entrez ID:10992; OMIM: 605591; Uniprot ID:SF3B2_HUMAN; ENSEMBL ID: ENSG00000087365; HGNC ID: 10769 |
| Relate to Another Database: | SFARIGene; denovo-db |
| Location(AA) | Modification | |
|---|---|---|
| 201 | Phosphothreonine. | |
| 217 | Phosphothreonine. | |
| 275 | N6-acetyllysine. | |
| 289 | Phosphoserine. | |
| 307 | Phosphoserine. | |
| 309 | Phosphoserine. | |
| 311 | Phosphothreonine. | |
| 343 | Phosphoserine. | |
| 360 | Phosphoserine. | |
| 362 | Phosphoserine. | |
| 416 | Phosphoserine. | |
| 431 | Phosphoserine. | |
| 435 | Phosphoserine. | |
| 436 | Phosphoserine. | |
| 778 | Phosphoserine. | |
| 780 | Phosphothreonine. | |
| Location(AA) | Modifications | Resource |
|---|---|---|
| 280 | Phosphoserine | Phospho.ELM 6.0 |
| 284 | Phosphoserine. | Swiss-Prot 53.0 |
| 284 | Phosphoserine | Phospho.ELM 6.0 |
| 286 | Phosphoserine | Phospho.ELM 6.0 |
| 286 | Phosphoserine. | Swiss-Prot 53.0 |
| 339 | Phosphoserine. | Swiss-Prot 53.0 |
| 393 | Phosphoserine. | Swiss-Prot 53.0 |
| 408 | Phosphoserine. | Swiss-Prot 53.0 |
| 412 | Phosphoserine. | Swiss-Prot 53.0 |
| 413 | Phosphoserine. | Swiss-Prot 53.0 |
| Location(AA) | Modification | Resource |
|---|---|---|
| 38 | Phosphothreonine(PKA) | HMM predict |
| 61 | O-linked | HMM predict |
| 210 | Phosphothreonine(MAPK) | HMM predict |
| 222 | Methylarginine | HMM predict |
| 266 | Phosphoserine(ATM) | HMM predict |
| 279 | Phosphoserine(CK1) | HMM predict |
| 284 | Phosphoserine(IKK) | HMM predict |
| 324 | Phosphoserine(CK1) | HMM predict |
| 337 | Phosphoserine(CK2) | HMM predict |
| 339 | Phosphoserine(IKK) | HMM predict |
| 348 | Sulfotyrosine | HMM predict |
| 356 | Phosphotyrosine(Syk) | HMM predict |
| 408 | Phosphoserine(CK2) | HMM predict |
| 412 | Phosphoserine(CK2) | HMM predict |
| 412 | Phosphoserine(CK1) | HMM predict |
| 413 | Phosphoserine(CK2) | HMM predict |
| 413 | Phosphoserine(CK1) | HMM predict |
| 525 | Phosphothreonine(PKC) | HMM predict |
| 557 | Phosphothreonine(PKC) | HMM predict |
| 569 | Sulfotyrosine | HMM predict |
| 632 | Phosphoserine(CDC2) | HMM predict |
| 675 | Phosphothreonine(CK2) | HMM predict |
| 691 | Phosphoserine(CK1) | HMM predict |
| 691 | Phosphoserine(CK2) | HMM predict |
| 691 | Phosphoserine(ATM) | HMM predict |
| 695 | Phosphoserine(CK2) | HMM predict |
| 695 | Phosphoserine(CK1) | HMM predict |
| 696 | Phosphoserine(CK1) | HMM predict |
| 696 | Phosphoserine(CK2) | HMM predict |
| 704 | Phosphoserine(CK2) | HMM predict |
| 704 | Phosphoserine(ATM) | HMM predict |
| 704 | Phosphoserine(CK1) | HMM predict |
| 757 | Phosphothreonine(MAPK) | HMM predict |
| 864 | Phosphoserine(PKC) | HMM predict |
| 867 | Phosphotyrosine(Syk) | HMM predict |
- RefSeq ID: NM_006842
- Location:chr11 65576391-65592957
- strand:+
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| ETS1 | Jurkat | GSE17954 | 65575503 | 65576988 | 1485 | 146 |
| Fos | K562 | GSE19551 | 65575886 | 65576620 | 734 | 139 |
| H3ac | HepG2 | E | 65575092 | 65575841 | 749 | 925 |
| PHF8 | 293T | GSE20725 | 65575592 | 65576945 | 1353 | 123 |
| PHF8 | HeLa | GSE20725 | 65575537 | 65577166 | 1629 | 40 |
| TFAP2C | MCF7 | GSE21234 | 65575805 | 65576587 | 782 | 196 |
| p130 | Quiescent | GSE19898 | 65575693 | 65575897 | 204 | 597 |
| p130 | Senescent | GSE19898 | 65575919 | 65576273 | 354 | 296 |
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| hScc1 | Bcell | GSE12603 | 65593362 | 65593694 | 332 | 571 |
| p130 | shRbQuiescent | GSE19898 | 65593208 | 65593704 | 496 | 499 |
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| CTCF | CD4 | GSE12889 | 65592267 | 65592552 | 285 | 0 |
| CTCF | CD4 | SISSRdata | 65592267 | 65592552 | 285 | 0 |
| GABP | Hela | GSE8489 | 65576630 | 65577322 | 692 | 0 |
| GABP | k562 | GSE8489 | 65576368 | 65577418 | 1050 | 0 |
| H3ac | HepG2 | E | 65576516 | 65577418 | 902 | 0 |
| H3ac | HepG2 | E | 65578557 | 65578858 | 301 | 0 |
| NRSF | pAb | Jurkat | 65576302 | 65576516 | 214 | 0 |
| P300 | T30-glioblastoma | GSE21026 | 65575609 | 65577359 | 1750 | 0 |
| PHF8 | Hs68plusFBS | GSE20725 | 65575527 | 65577448 | 1921 | 0 |
| Rb | Quiescent | GSE19898 | 65576199 | 65576755 | 556 | 0 |
| Rb | Senescent | GSE19898 | 65576139 | 65576671 | 532 | 0 |
| Rb | shRbQuiescent | GSE19898 | 65576347 | 65576613 | 266 | 0 |
| Rb | shRbQuiescent | GSE19898 | 65589281 | 65589553 | 272 | 0 |
| TAF | Hela | GSE8489 | 65576588 | 65577322 | 734 | 0 |
| TAF | k562 | GSE8489 | 65576516 | 65577418 | 902 | 0 |
| hScc1 | Bcell | GSE12603 | 65592470 | 65592988 | 518 | 0 |
| p130 | Quiescent | GSE19898 | 65576170 | 65576879 | 709 | 0 |
| p130 | Senescent | GSE19898 | 65576294 | 65576629 | 335 | 0 |
| p130 | shRbQuiescent | GSE19898 | 65576301 | 65576986 | 685 | 0 |
| p130 | shRbSenescent | GSE19898 | 65576262 | 65576996 | 734 | 0 |
Validated miRNA targets| Cluster ID | Plue Type | Plus Gene Name | Plus Chromosome | Plus Start | Plus End | Overlap Length | Minus Type | Minus Gene Name | Minus Chromosome | Minus Star | Minus End | Type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 4733 | mRNA | SF3B2 | chr11 | 65576391 | 65592958 | 1635 | EST | chr11 | 65591323 | 65593646 | Non-exonic Bidirectional (NOB) pairs | |