AutismKB 2.0

Annotation Detail for KIF2C


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Basic Information Top
Gene Symbol:KIF2C ( KNSL6,MCAK )
Gene Full Name: kinesin family member 2C
Band: 1p34.1
Quick LinksEntrez ID:11004; OMIM: 604538; Uniprot ID:KIF2C_HUMAN; ENSEMBL ID: ENSG00000142945; HGNC ID: 6393
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
95Phosphoserine; by STK12.
101Microtubule tip localization signal.
106Phosphoserine.
109Phosphoserine (By similarity).
111Phosphoserine (By similarity).
115Phosphoserine.
166Phosphoserine.
179Phosphoserine.
192Phosphoserine (By similarity).
418Nuclear localization signal (Potential).
628Phosphoserine.
629Phosphoserine.
632Phosphoserine.
633Phosphoserine.
Location(AA) Modifications Resource
95Phosphoserine (Aurora B)Phospho.ELM 6.0
628Phosphoserine.Swiss-Prot 53.0
629Phosphoserine.Swiss-Prot 53.0
632Phosphoserine.Swiss-Prot 53.0
633Phosphoserine.Swiss-Prot 53.0
Location(AA) Modification Resource
85N-linkedHMM predict
116Phosphothreonine(PKC)HMM predict
166Phosphoserine(CAMK2)HMM predict
192Phosphoserine(PKA)HMM predict
398Phosphotyrosine(EGFR)HMM predict
466N-linkedHMM predict
509Phosphothreonine(PKC)HMM predict
537Phosphothreonine(CDK)HMM predict
537Phosphothreonine(MAPK)HMM predict
537Phosphothreonine(CDC2)HMM predict
542Phosphoserine(PKG)HMM predict
592Phosphoserine(IKK)HMM predict
592Phosphoserine(ATM)HMM predict
628Phosphoserine(CK1)HMM predict
629Phosphoserine(ATM)HMM predict
674Phosphotyrosine(INSR)HMM predict
674SulfotyrosineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_006845
  • Location:chr1 44978137-45005992
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 44977876 44978192 316 104
P300 T0-glioblastomaGSE21026 44977414 44978457 1043 202
p130 SenescentGSE19898 44977539 44978651 1112 43
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3ac HepG2E 45006783 45007369 586 1084
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
E2F4 G0GSE7516 44977848 44978872 1024 0
E2F4 SGSE7516 44977848 44979340 1492 0
ETS1 JurkatGSE17954 44977630 44978674 1044 0
H3ac HepG2E 44977848 44979267 1419 0
LIN54 G0GSE7516 44977848 44978792 944 0
LIN54 SGSE7516 44977848 44978792 944 0
LIN9 G0GSE7516 44977408 44979340 1932 0
LIN9 SGSE7516 44977551 44979340 1789 0
TAF k562GSE8489 44977983 44979340 1357 0
p130 QuiescentGSE19898 44977818 44978728 910 0
p130 shRbQuiescentGSE19898 44977719 44978768 1049 0
p130 shRbSenescentGSE19898 44977673 44978628 955 0
p130 G0GSE7516 44977848 44979340 1492 0
p130 SGSE7516 44977848 44979340 1492 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
706 mRNA KIF2C chr1 44874643 44902506 137 EST chr1 44893801 44896942Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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