AutismKB 2.0

Annotation Detail for RIPK3


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Basic Information Top
Gene Symbol:RIPK3 ( RIP3 )
Gene Full Name: receptor-interacting serine-threonine kinase 3
Band: 14q12
Quick LinksEntrez ID:11035; OMIM: 605817; Uniprot ID:RIPK3_HUMAN; ENSEMBL ID: ENSG00000129465; HGNC ID: 10021
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
199Phosphoserine; by autocatalysis.
466RIP homotypic interaction motif (RHIM).
Location(AA) Modifications Resource
Location(AA) Modification Resource
99N-linkedHMM predict
170O-linkedHMM predict
170Phosphoserine(ATM)HMM predict
170Phosphoserine(IKK)HMM predict
172Phosphoserine(IKK)HMM predict
176O-linkedHMM predict
185Phosphotyrosine(Jak)HMM predict
199Phosphoserine(PKG)HMM predict
252Phosphothreonine(MAPK)HMM predict
316Phosphoserine(CK1)HMM predict
316Phosphoserine(PKG)HMM predict
360Phosphoserine(ATM)HMM predict
391Phosphoserine(IKK)HMM predict
398Phosphothreonine(CDK)HMM predict
398Phosphothreonine(MAPK)HMM predict
410Phosphoserine(CDC2)HMM predict
410O-linkedHMM predict
412O-linkedHMM predict
413O-linkedHMM predict
413Phosphoserine(IKK)HMM predict
413O-linkedHMM predict
414O-linkedHMM predict
414O-linkedHMM predict
416O-linkedHMM predict
416O-linkedHMM predict
416O-linkedHMM predict
418Phosphoserine(CDK)HMM predict
418Phosphoserine(CDC2)HMM predict
422MethylarginineHMM predict
438Phosphothreonine(CDC2)HMM predict
438Phosphothreonine(CDK)HMM predict
454N-linkedHMM predict
465Phosphotyrosine(INSR)HMM predict
465Phosphotyrosine(Syk)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_006871
  • Location:chr14 23875067-23879081
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Oct1 HelaGSE14283 23887888 23887920 32 8823
No data
No data
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018