AutismKB 2.0

Annotation Detail for CHD2


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Basic Information Top
Gene Symbol:CHD2 ( DKFZp547I1315,DKFZp686E01200,DKFZp781D1727,FLJ38614 )
Gene Full Name: chromodomain helicase DNA binding protein 2
Band: 15q26.1
Quick LinksEntrez ID:1106; OMIM: 602119; Uniprot ID:CHD2_HUMAN; ENSEMBL ID: ENSG00000173575; HGNC ID: 1917
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
240Phosphothreonine.
242Phosphoserine.
620DEAH box.
747Phosphoserine.
1012Phosphoserine.
1801Phosphoserine.
1807Phosphoserine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
8Phosphoserine(CK2)HMM predict
8Phosphoserine(CK2)HMM predict
8PhosphoserineHMM predict
13Phosphoserine(CK1)HMM predict
14Phosphoserine(CK1)HMM predict
17Phosphoserine(IKK)HMM predict
18N-linkedHMM predict
20Phosphoserine(CK2)HMM predict
23Phosphoserine(CK2)HMM predict
25O-linkedHMM predict
25Phosphoserine(CK2)HMM predict
29Phosphoserine(IKK)HMM predict
31O-linkedHMM predict
33Phosphoserine(IKK)HMM predict
35Phosphoserine(CK1)HMM predict
35Phosphoserine(ATM)HMM predict
35Phosphoserine(IKK)HMM predict
37Phosphoserine(CK2)HMM predict
37Phosphoserine(IKK)HMM predict
39Phosphoserine(CK2)HMM predict
43O-linkedHMM predict
47Phosphoserine(IKK)HMM predict
54N-linkedHMM predict
55Phosphoserine(CK1)HMM predict
55Phosphoserine(IKK)HMM predict
56Phosphoserine(CK1)HMM predict
57Phosphoserine(CK2)HMM predict
59Phosphoserine(CK1)HMM predict
60Phosphoserine(CK1)HMM predict
62Phosphoserine(CK1)HMM predict
62Phosphoserine(ATM)HMM predict
62Phosphoserine(IKK)HMM predict
64Phosphoserine(IKK)HMM predict
66Phosphoserine(IKK)HMM predict
68Phosphoserine(CK1)HMM predict
73Phosphoserine(CK1)HMM predict
73Phosphoserine(IKK)HMM predict
75Phosphoserine(ATM)HMM predict
113N-linkedHMM predict
129Phosphoserine(CK2)HMM predict
130Phosphoserine(CK1)HMM predict
130Phosphoserine(CK2)HMM predict
130Phosphoserine(ATM)HMM predict
130Phosphoserine(IKK)HMM predict
132O-linkedHMM predict
132Phosphoserine(CK1)HMM predict
132Phosphoserine(IKK)HMM predict
134Phosphoserine(ATM)HMM predict
136Phosphoserine(CDC2)HMM predict
136PhosphoserineHMM predict
156Phosphoserine(CK1)HMM predict
156Phosphoserine(CK2)HMM predict
168Phosphoserine(CK1)HMM predict
168Phosphoserine(CK2)HMM predict
185Phosphothreonine(PKC)HMM predict
207Phosphoserine(CK2)HMM predict
208Phosphoserine(CK2)HMM predict
208Phosphoserine(CK2)HMM predict
208Phosphoserine(ATM)HMM predict
208PhosphoserineHMM predict
222Phosphothreonine(PKC)HMM predict
274O-linkedHMM predict
281O-linkedHMM predict
298Phosphothreonine(CK2)HMM predict
326Phosphoserine(CK1)HMM predict
448N-linkedHMM predict
449N-linkedHMM predict
573Phosphothreonine(PKC)HMM predict
762S-palmitoylHMM predict
828Phosphothreonine(PKC)HMM predict
953N-linkedHMM predict
954N-linkedHMM predict
959N-linkedHMM predict
960Phosphoserine(PKB)HMM predict
1010O-linkedHMM predict
1068Phosphotyrosine(INSR)HMM predict
1068Phosphotyrosine(SRC)HMM predict
1075Phosphoserine(CDC2)HMM predict
1083N-linkedHMM predict
1085Phosphoserine(CK2)HMM predict
1087Phosphoserine(CK1)HMM predict
1087Phosphoserine(CK2)HMM predict
1099Phosphoserine(IKK)HMM predict
1101Phosphoserine(IKK)HMM predict
1103Phosphoserine(CK2)HMM predict
1103Phosphoserine(IKK)HMM predict
1108Phosphoserine(CK2)HMM predict
1108PhosphoserineHMM predict
1117MethylarginineHMM predict
1132Phosphothreonine(CK2)HMM predict
1188Phosphotyrosine(Syk)HMM predict
1209Phosphothreonine(PKC)HMM predict
1278Phosphotyrosine(INSR)HMM predict
1365Phosphoserine(CDK)HMM predict
1371N-linkedHMM predict
1373Phosphoserine(CK1)HMM predict
1373Phosphoserine(CK2)HMM predict
1420Phosphoserine(PKG)HMM predict
1429Phosphoserine(CK2)HMM predict
1438Phosphoserine(CK1)HMM predict
1441Phosphoserine(PKG)HMM predict
1521Phosphoserine(CK2)HMM predict
1560Phosphoserine(PKG)HMM predict
1560Phosphoserine(CK2)HMM predict
1590Phosphoserine(CK1)HMM predict
1593Phosphoserine(ATM)HMM predict
1624Phosphotyrosine(Syk)HMM predict
1688Phosphoserine(PKC)HMM predict
1688Phosphoserine(PKB)HMM predict
1705Phosphoserine(CK2)HMM predict
1715Phosphotyrosine(Syk)HMM predict
1785O-linkedHMM predict
1789Phosphoserine(MAPK)HMM predict
1789Phosphoserine(IKK)HMM predict
1792Phosphoserine(ATM)HMM predict
1792Phosphoserine(IKK)HMM predict
1795Phosphoserine(IKK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001042572
  • Location:chr15 91244422-91293464
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 91226784 91227478 694 17292
FOXA1 MCF7GSE15244 91225785 91226720 935 18170
FOXA1 eGFPGSE10845 91225785 91226720 935 18170
Fos K562GSE19551 91225993 91227092 1099 17880
H3ac HepG2E 91225345 91226505 1160 18498
H3ac HepG2E 91227778 91228732 954 16168
PHF8 293TGSE20725 91226082 91227578 1496 17593
PHF8 HeLaGSE20725 91226920 91228163 1243 16881
PHF8 Hs68plusFBSGSE20725 91225930 91227700 1770 17608
TAF HelaGSE8489 91227814 91230982 3168 15025
TAF HelaGSE8489 91242255 91244148 1893 1221
TAF k562GSE8489 91227814 91229010 1196 16011
TFAP2C MCF7GSE21234 91226004 91226877 873 17982
hScc1 BcellGSE12603 91227049 91227455 406 17171
p130 QuiescentGSE19898 91226993 91227163 170 17345
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 91262159 91262536 377 0
CTCF CD4SISSRdata 91262159 91262536 377 0
CTCF G2GSE9613 91248356 91248755 399 0
CTCF G2GSE9613 91262038 91262476 438 0
ETS1 JurkatGSE17954 91247772 91249238 1466 0
FOXA1 MCF7GSE15244 91261828 91262410 582 0
FOXA1 eGFPGSE10845 91261828 91262410 582 0
Fos K562GSE19551 91248330 91248928 598 0
FoxA1 MCF7MACSdata 91251053 91251300 247 0
H3K4me3 colorectalcancer 91245215 91245650 435 0
H3ac HepG2E 91244553 91245685 1132 0
H3ac HepG2E 91247999 91248466 467 0
H3ac HepG2E 91248792 91250294 1502 0
H3ac HepG2E 91250618 91251237 619 0
H3ac HepG2E 91255974 91256581 607 0
Myc K562GSE19551 91262111 91262597 486 0
NRSF mAbJurkat 91244841 91245685 844 0
P300 T0-glioblastomaGSE21026 91261626 91262586 960 0
P300 T30-glioblastomaGSE21026 91261352 91262705 1353 0
Pol2 GM12878GSE19551 91244214 91245096 882 0
Pol2 GM12878GSE19551 91248080 91249646 1566 0
PolII HeLaGSE12783 91241617 91252750 11133 0
Rb shRbSenescenceGSE19898 91259242 91259411 169 0
TAF HelaGSE8489 91244443 91252017 7574 0
TAF HelaGSE8489 91278884 91279133 249 0
TAF k562GSE8489 91244621 91246696 2075 0
hScc1 BcellGSE12603 91248394 91248792 398 0
hScc1 BcellGSE12603 91261900 91262476 576 0
hScc1 CdLSGSE12603 91261972 91262551 579 0
p130 QuiescentGSE19898 91248176 91248628 452 0
p130 SenescentGSE19898 91248166 91248586 420 0
p130 shRbQuiescentGSE19898 91248239 91248481 242 0
p130 shRbSenescentGSE19898 91248203 91248659 456 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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