AutismKB 2.0

Annotation Detail for TMEM115


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Basic Information Top
Gene Symbol:TMEM115 ( PL6 )
Gene Full Name: transmembrane protein 115
Band: 3p21.31
Quick LinksEntrez ID:11070; OMIM: 607069; Uniprot ID:TM115_HUMAN; ENSEMBL ID: ENSG00000126062; HGNC ID: 30055
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
320Phosphoserine.
Location(AA) Modifications Resource
320Phosphoserine (By similarity).Swiss-Prot 53.0
Location(AA) Modification Resource
120Phosphothreonine(PKC)HMM predict
167Phosphoserine(PKG)HMM predict
267Phosphoserine(IKK)HMM predict
269O-linkedHMM predict
320Phosphoserine(CDC2)HMM predict
329Phosphothreonine(CDC2)HMM predict
329Phosphothreonine(MAPK)HMM predict
329Phosphothreonine(CDK)HMM predict
329PhosphothreonineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_007024
  • Location:chr3 50367183-50371942
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ETS1 JurkatGSE17954 50371415 50372899 1484 215
P300 T0-glioblastomaGSE21026 50371741 50372394 653 125
P300 T30-glioblastomaGSE21026 50371307 50372676 1369 49
VDR GM10861-UnstimGSE22484 50371483 50372759 1276 179
p130 SenescentGSE19898 50371994 50372273 279 191
p130 shRbQuiescentGSE19898 50372136 50372644 508 448
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Gata2 K562GSE18868 50366739 50367204 465 212
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 50368865 50369311 446 0
CTCF G2GSE9613 50370686 50372056 1370 0
H3K4me3 colorectalcancer 50369570 50370686 1116 0
H3ac HepG2E 50368416 50371686 3270 0
PHF8 HeLaGSE20725 50371220 50372215 995 0
PHF8 Hs68plusFBSGSE20725 50371119 50372644 1525 0
hScc1 G2GSE9613 50370827 50371293 466 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018