AutismKB 2.0

Annotation Detail for TRIOBP


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Basic Information Top
Gene Symbol:TRIOBP ( DFNB28,FLJ39315,KIAA1662,TARA,dJ37E16.4 )
Gene Full Name: TRIO and F-actin binding protein
Band: 22q13.1
Quick LinksEntrez ID:11078; OMIM: 609761; Uniprot ID:TARA_HUMAN; ENSEMBL ID: ENSG00000100101,ENSG00000100106; HGNC ID: 17009
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
810Phosphothreonine.
1945Phosphotyrosine.
1949Phosphoserine.
1955Phosphoserine.
1983Phosphoserine.
Location(AA) Modifications Resource
810Phosphothreonine.Swiss-Prot 53.0
810PhosphothreoninePhospho.ELM 6.0
1955Phosphoserine (By similarity).Swiss-Prot 53.0
Location(AA) Modification Resource
37Phosphotyrosine(EGFR)HMM predict
42Phosphoserine(CDC2)HMM predict
42Phosphoserine(CDK)HMM predict
65O-linkedHMM predict
65Phosphoserine(IKK)HMM predict
67Phosphoserine(IKK)HMM predict
69Phosphoserine(IKK)HMM predict
73Phosphoserine(IKK)HMM predict
88O-linkedHMM predict
88Phosphoserine(CDC2)HMM predict
99O-linkedHMM predict
121Phosphoserine(IKK)HMM predict
125Phosphoserine(IKK)HMM predict
132Phosphoserine(ATM)HMM predict
135O-linkedHMM predict
135O-linkedHMM predict
136O-linkedHMM predict
136Phosphoserine(IKK)HMM predict
137O-linkedHMM predict
137Phosphoserine(CDC2)HMM predict
140Phosphoserine(IKK)HMM predict
146O-linkedHMM predict
147Phosphoserine(IKK)HMM predict
148N-linkedHMM predict
151Phosphoserine(CK1)HMM predict
151Phosphoserine(ATM)HMM predict
179MethylarginineHMM predict
187Phosphoserine(ATM)HMM predict
197Phosphoserine(CDC2)HMM predict
197Phosphoserine(CDK)HMM predict
232Phosphoserine(CK1)HMM predict
238Phosphoserine(PKG)HMM predict
239Phosphothreonine(PKA)HMM predict
244O-linkedHMM predict
247O-linkedHMM predict
250Phosphoserine(IKK)HMM predict
254Phosphoserine(IKK)HMM predict
255Phosphothreonine(CK2)HMM predict
257O-linkedHMM predict
257Phosphoserine(ATM)HMM predict
257Phosphoserine(IKK)HMM predict
260Phosphoserine(CAMK2)HMM predict
272Phosphothreonine(PKC)HMM predict
280Phosphoserine(CDC2)HMM predict
280Phosphoserine(CDK)HMM predict
289Phosphothreonine(PKA)HMM predict
290O-linkedHMM predict
294Phosphoserine(PKB)HMM predict
300O-linkedHMM predict
304Phosphoserine(PKB)HMM predict
309O-linkedHMM predict
310O-linkedHMM predict
314Phosphoserine(PKG)HMM predict
314Phosphoserine(CK2)HMM predict
319O-linkedHMM predict
319Phosphothreonine(MAPK)HMM predict
324Phosphoserine(PKG)HMM predict
329O-linkedHMM predict
329Phosphothreonine(MAPK)HMM predict
335O-linkedHMM predict
339O-linkedHMM predict
339Phosphothreonine(MAPK)HMM predict
344O-linkedHMM predict
344Phosphoserine(CDC2)HMM predict
344Phosphoserine(CDK)HMM predict
344Phosphoserine(IKK)HMM predict
344Phosphoserine(PKB)HMM predict
344PhosphoserineHMM predict
346Phosphoserine(CK1)HMM predict
357Phosphoserine(CK1)HMM predict
372Phosphothreonine(CDC2)HMM predict
392Phosphoserine(CDC2)HMM predict
392Phosphoserine(CDK)HMM predict
392Phosphoserine(IKK)HMM predict
392Phosphoserine(PKB)HMM predict
394N-linkedHMM predict
419Phosphoserine(CDC2)HMM predict
419Phosphoserine(CDK)HMM predict
424Phosphothreonine(PKA)HMM predict
442Phosphoserine(CDC2)HMM predict
442Phosphoserine(CDK)HMM predict
442PhosphoserineHMM predict
447Phosphothreonine(PKA)HMM predict
450N-linkedHMM predict
468Phosphoserine(CDC2)HMM predict
468Phosphoserine(CDK)HMM predict
473Phosphothreonine(PKA)HMM predict
491Phosphoserine(CDC2)HMM predict
491Phosphoserine(CDK)HMM predict
491PhosphoserineHMM predict
496Phosphothreonine(PKA)HMM predict
499N-linkedHMM predict
517Phosphoserine(CDC2)HMM predict
517Phosphoserine(CDK)HMM predict
522Phosphothreonine(PKA)HMM predict
540Phosphoserine(CDC2)HMM predict
540Phosphoserine(CDK)HMM predict
548N-linkedHMM predict
566Phosphoserine(CDC2)HMM predict
566Phosphoserine(CDK)HMM predict
571Phosphothreonine(PKA)HMM predict
589Phosphoserine(CDC2)HMM predict
589Phosphoserine(CDK)HMM predict
594Phosphothreonine(PKA)HMM predict
597N-linkedHMM predict
615Phosphoserine(CDC2)HMM predict
615Phosphoserine(CDK)HMM predict
620Phosphothreonine(PKA)HMM predict
638Phosphoserine(CDC2)HMM predict
638Phosphoserine(CDK)HMM predict
638Phosphoserine(IKK)HMM predict
638Phosphoserine(PKB)HMM predict
640N-linkedHMM predict
647Phosphoserine(IKK)HMM predict
662Phosphoserine(CDC2)HMM predict
662Phosphoserine(CDK)HMM predict
662Phosphoserine(IKK)HMM predict
662Phosphoserine(PKB)HMM predict
664N-linkedHMM predict
686Phosphoserine(CDC2)HMM predict
686Phosphoserine(CDK)HMM predict
686Phosphoserine(IKK)HMM predict
686Phosphoserine(PKB)HMM predict
710Phosphoserine(CDC2)HMM predict
710Phosphoserine(CDK)HMM predict
710Phosphoserine(IKK)HMM predict
710Phosphoserine(PKB)HMM predict
712N-linkedHMM predict
736N-linkedHMM predict
758Phosphoserine(CDC2)HMM predict
758Phosphoserine(CDK)HMM predict
758Phosphoserine(IKK)HMM predict
758Phosphoserine(PKB)HMM predict
760N-linkedHMM predict
782Phosphoserine(CDC2)HMM predict
782Phosphoserine(CDK)HMM predict
787Phosphothreonine(PKA)HMM predict
805Phosphoserine(CDC2)HMM predict
882Phosphoserine(CDC2)HMM predict
887Phosphothreonine(PKA)HMM predict
894N-linkedHMM predict
896Phosphoserine(CDC2)HMM predict
896Phosphoserine(CDK)HMM predict
896Phosphoserine(PKB)HMM predict
914O-linkedHMM predict
923Phosphoserine(CDC2)HMM predict
923Phosphoserine(CDK)HMM predict
923Phosphoserine(IKK)HMM predict
923Phosphoserine(PKB)HMM predict
923PhosphoserineHMM predict
927Phosphoserine(PKA)HMM predict
949Phosphothreonine(PKC)HMM predict
951Phosphoserine(CDC2)HMM predict
951Phosphoserine(IKK)HMM predict
953Phosphoserine(PKA)HMM predict
978Phosphoserine(CK1)HMM predict
980O-linkedHMM predict
988Phosphothreonine(PKA)HMM predict
989O-linkedHMM predict
993O-linkedHMM predict
993Phosphoserine(CDC2)HMM predict
993Phosphoserine(IKK)HMM predict
996Phosphotyrosine(SRC)HMM predict
1006O-linkedHMM predict
1006Phosphoserine(CDC2)HMM predict
1006Phosphoserine(MAPK)HMM predict
1006Phosphoserine(CDK)HMM predict
1010O-linkedHMM predict
1010Phosphoserine(ATM)HMM predict
1028Phosphoserine(CDC2)HMM predict
1032Phosphotyrosine(Abl)HMM predict
1049O-linkedHMM predict
1075Phosphoserine(CDC2)HMM predict
1075Phosphoserine(PKB)HMM predict
1092Phosphoserine(CK2)HMM predict
1124Phosphoserine(CDC2)HMM predict
1124Phosphoserine(CDK)HMM predict
1124Phosphoserine(IKK)HMM predict
1124Phosphoserine(PKB)HMM predict
1124PhosphoserineHMM predict
1173Phosphoserine(IKK)HMM predict
1176Phosphoserine(CDC2)HMM predict
1176Phosphoserine(CDK)HMM predict
1194Phosphothreonine(PKC)HMM predict
1205Phosphoserine(CK1)HMM predict
1205Phosphoserine(IKK)HMM predict
1228Phosphoserine(CDC2)HMM predict
1228Phosphoserine(PKB)HMM predict
1243Phosphoserine(CDC2)HMM predict
1243Phosphoserine(CDK)HMM predict
1245O-linkedHMM predict
1245Phosphoserine(CDC2)HMM predict
1245Phosphoserine(ATM)HMM predict
1248Phosphoserine(IKK)HMM predict
1252O-linkedHMM predict
1253MethylarginineHMM predict
1255O-linkedHMM predict
1255Phosphoserine(PKA)HMM predict
1270Phosphotyrosine(INSR)HMM predict
1270Phosphotyrosine(Syk)HMM predict
1301Phosphoserine(CAMK2)HMM predict
1301Phosphoserine(CDC2)HMM predict
1318Phosphoserine(PKA)HMM predict
1318Phosphoserine(PKG)HMM predict
1318Phosphoserine(PKB)HMM predict
1332Phosphoserine(ATM)HMM predict
1336Phosphoserine(IKK)HMM predict
1347Phosphoserine(PKG)HMM predict
1348Phosphoserine(CDC2)HMM predict
1348Phosphoserine(IKK)HMM predict
1348Phosphoserine(PKB)HMM predict
1369Phosphoserine(PKA)HMM predict
1369Phosphoserine(PKG)HMM predict
1392Phosphoserine(CDC2)HMM predict
1392Phosphoserine(CDK)HMM predict
1399O-linkedHMM predict
1399O-linkedHMM predict
1402Phosphothreonine(CDC2)HMM predict
1402Phosphothreonine(MAPK)HMM predict
1402Phosphothreonine(CDK)HMM predict
1409Phosphothreonine(PKC)HMM predict
1429Phosphoserine(ATM)HMM predict
1436O-linkedHMM predict
1436Phosphoserine(ATM)HMM predict
1510Phosphoserine(CDC2)HMM predict
1514Phosphoserine(CDC2)HMM predict
1514Phosphoserine(MAPK)HMM predict
1526Phosphoserine(CK1)HMM predict
1526Phosphoserine(ATM)HMM predict
1528Phosphoserine(IKK)HMM predict
1535O-linkedHMM predict
1628Phosphoserine(CK1)HMM predict
1628Phosphoserine(ATM)HMM predict
1650Phosphoserine(IKK)HMM predict
1656O-linkedHMM predict
1660O-linkedHMM predict
1662O-linkedHMM predict
1711Phosphoserine(CK1)HMM predict
1714O-linkedHMM predict
1740Phosphoserine(CDC2)HMM predict
1796O-linkedHMM predict
1796Phosphoserine(MAPK)HMM predict
1796Phosphoserine(IKK)HMM predict
1798O-linkedHMM predict
1798O-linkedHMM predict
1800O-linkedHMM predict
1930MethylarginineHMM predict
1955Phosphoserine(CDC2)HMM predict
1961Phosphothreonine(CDC2)HMM predict
1961Phosphothreonine(MAPK)HMM predict
1961Phosphothreonine(CDK)HMM predict
1965Phosphothreonine(CDC2)HMM predict
1965Phosphothreonine(MAPK)HMM predict
1965Phosphothreonine(CDK)HMM predict
1995O-linkedHMM predict
2023Phosphoserine(CK1)HMM predict
2095Phosphoserine(ATM)HMM predict
2120Phosphoserine(CK1)HMM predict
2171Phosphoserine(CK1)HMM predict
2175Phosphoserine(CK1)HMM predict
2317Phosphothreonine(PKC)HMM predict
2321Phosphotyrosine(SRC)HMM predict
2325Phosphotyrosine(Jak)HMM predict
2325Phosphotyrosine(Syk)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001039141
  • Location:chr22 36423573-36502507
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 36422608 36422889 281 825
Rb SenescentGSE19898 36422630 36422944 314 787
hScc1 BcellGSE12603 36422608 36422980 372 780
hScc1 CdLSGSE12603 36422608 36422788 180 876
p130 SenescentGSE19898 36421584 36421836 252 1864
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 36450381 36450891 510 0
CTCF G2GSE9613 36461090 36461474 384 0
Fos K562GSE19551 36471883 36472388 505 0
H3ac HepG2E 36469487 36469926 439 0
H3ac HepG2E 36471164 36471536 372 0
TFAP2C MCF7GSE21234 36436529 36437272 743 0
hScc1 BcellGSE12603 36449760 36450822 1062 0
hScc1 BcellGSE12603 36451239 36451640 401 0
hScc1 BcellGSE12603 36452117 36452475 358 0
hScc1 BcellGSE12603 36460879 36461414 535 0
p130 SenescentGSE19898 36423570 36423838 268 0
p130 shRbSenescentGSE19898 36472029 36472169 140 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
17453 mRNA HRIHFB2122 chr22 36466747 36495016 57 EST chr22 36464898 36472389Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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