AutismKB 2.0

Annotation Detail for ADAMTS13


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Basic Information Top
Gene Symbol:ADAMTS13 ( C9orf8,DKFZp434C2322,FLJ42993,MGC118899,MGC118900,TTP,VWFCP,vWF-CP )
Gene Full Name: ADAM metallopeptidase with thrombospondin type 1 motif, 13
Band: 9q34.2
Quick LinksEntrez ID:11093; OMIM: 604134; Uniprot ID:ATS13_HUMAN; ENSEMBL ID: ENSG00000160323; HGNC ID: 1366
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
142N-linked (GlcNAc...) (Potential).
146N-linked (GlcNAc...) (Potential).
500Cell attachment site (Potential).
552N-linked (GlcNAc...) (Potential).
579N-linked (GlcNAc...) (Potential).
614N-linked (GlcNAc...).
667N-linked (GlcNAc...).
707N-linked (GlcNAc...) (Potential).
828N-linked (GlcNAc...) (Potential).
1235N-linked (GlcNAc...) (Potential).
1354N-linked (GlcNAc...).
Location(AA) Modifications Resource
142N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
146N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
552N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
579N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
614N-linked (GlcNAc...).Swiss-Prot 53.0
667N-linked (GlcNAc...).Swiss-Prot 53.0
707N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
828N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1235N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1354N-linked (GlcNAc...).Swiss-Prot 53.0
Location(AA) Modification Resource
27S-palmitoylHMM predict
51Phosphoserine(CDC2)HMM predict
51Phosphoserine(ATM)HMM predict
62Phosphoserine(CDC2)HMM predict
142N-linkedHMM predict
146N-linkedHMM predict
203Phosphoserine(ATM)HMM predict
240Phosphoserine(IKK)HMM predict
263Phosphoserine(IKK)HMM predict
265S-palmitoylHMM predict
387C-linkedHMM predict
390C-linkedHMM predict
394Phosphoserine(CDC2)HMM predict
406Phosphothreonine(PKC)HMM predict
421MethylarginineHMM predict
461Phosphoserine(CDC2)HMM predict
461Phosphoserine(CDK)HMM predict
477Phosphoserine(ATM)HMM predict
538Phosphoserine(ATM)HMM predict
538Phosphoserine(PKA)HMM predict
552N-linkedHMM predict
553Phosphoserine(IKK)HMM predict
556Phosphoserine(CDC2)HMM predict
561Phosphoserine(IKK)HMM predict
575O-linkedHMM predict
579N-linkedHMM predict
612Phosphoserine(ATM)HMM predict
614N-linkedHMM predict
665Phosphotyrosine(INSR)HMM predict
667N-linkedHMM predict
742S-palmitoylHMM predict
811O-linkedHMM predict
814O-linkedHMM predict
814Phosphoserine(CK2)HMM predict
815Phosphoserine(IKK)HMM predict
828N-linkedHMM predict
848Phosphoserine(CK2)HMM predict
882Phosphoserine(CDC2)HMM predict
1012S-palmitoylHMM predict
1024S-palmitoylHMM predict
1098Phosphothreonine(PKA)HMM predict
1150O-linkedHMM predict
1151O-linkedHMM predict
1153O-linkedHMM predict
1170Phosphoserine(MAPK)HMM predict
1170Phosphoserine(CDC2)HMM predict
1186Phosphoserine(IKK)HMM predict
1288Phosphoserine(ATM)HMM predict
1312Phosphoserine(MAPK)HMM predict
1314O-linkedHMM predict
1316O-linkedHMM predict
1316Phosphoserine(CDC2)HMM predict
1316Phosphoserine(ATM)HMM predict
1365Phosphoserine(IKK)HMM predict
1383Phosphoserine(CK2)HMM predict
1384Phosphoserine(IKK)HMM predict
1384Phosphoserine(ATM)HMM predict
1400Phosphoserine(PKC)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_139025
  • Location:chr9 135276940-135314327
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
NFkBII GM10847GSE19485 135275145 135276106 961 1315
NFkBII GM12878GSE19485 135274895 135277496 2601 745
NFkBII GM12892GSE19485 135275042 135277457 2415 691
NFkBII GM18526GSE19485 135275151 135277297 2146 717
Sox2 hESGSE18292 135275297 135275504 207 1540
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 135284621 135284765 144 0
CTCF CD4SISSRdata 135284621 135284765 144 0
P300 T0-glioblastomaGSE21026 135278220 135278617 397 0
P300 T30-glioblastomaGSE21026 135277985 135278729 744 0
SRF GMOGSE8489 135287774 135288441 667 0
TFAP2C MCF7GSE21234 135292574 135293254 680 0
hScc1 BcellGSE12603 135283400 135283980 580 0
hScc1 BcellGSE12603 135284475 135285112 637 0
hScc1 BcellGSE12603 135293387 135293536 149 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-29a hsa-mir-29a 7 19247375
hsa-miR-29a* hsa-mir-29a 7 19247375
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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