AutismKB 2.0

Annotation Detail for PTPRT


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Basic Information Top
Gene Symbol:PTPRT ( KIAA0283,RPTPrho )
Gene Full Name: protein tyrosine phosphatase, receptor type, T
Band: 20q12-q13.11
Quick LinksEntrez ID:11122; OMIM: 608712; Uniprot ID:PTPRT_HUMAN; ENSEMBL ID: ENSG00000196090; HGNC ID: 9682
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
78N-linked (GlcNAc...) (Potential).
98N-linked (GlcNAc...) (Potential).
137N-linked (GlcNAc...) (Potential).
208N-linked (GlcNAc...) (Potential).
421N-linked (GlcNAc...) (Potential).
510N-linked (GlcNAc...) (Potential).
547N-linked (GlcNAc...) (Potential).
601N-linked (GlcNAc...) (Potential).
654N-linked (GlcNAc...) (Potential).
684N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
78N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
98N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
137N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
208N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
421N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
510N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
547N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
601N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
654N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
684N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
27Phosphoserine(PKG)HMM predict
78N-linkedHMM predict
84Phosphoserine(PKG)HMM predict
98N-linkedHMM predict
115Phosphoserine(CK1)HMM predict
116Phosphoserine(MAPK)HMM predict
137N-linkedHMM predict
176Phosphotyrosine(Jak)HMM predict
189S-palmitoylHMM predict
208N-linkedHMM predict
249Phosphoserine(PKG)HMM predict
249Phosphoserine(PKB)HMM predict
253Phosphoserine(IKK)HMM predict
261Phosphoserine(PKG)HMM predict
275Phosphoserine(IKK)HMM predict
370O-linkedHMM predict
378Phosphothreonine(PKC)HMM predict
404Phosphothreonine(PKC)HMM predict
421N-linkedHMM predict
435Phosphotyrosine(Syk)HMM predict
443Phosphothreonine(PKC)HMM predict
503SulfotyrosineHMM predict
510N-linkedHMM predict
513N-linkedHMM predict
523Phosphotyrosine(Syk)HMM predict
547N-linkedHMM predict
561O-linkedHMM predict
563O-linkedHMM predict
565Phosphothreonine(PKC)HMM predict
579Phosphothreonine(PKC)HMM predict
598Phosphothreonine(MAPK)HMM predict
601N-linkedHMM predict
654N-linkedHMM predict
684N-linkedHMM predict
688N-linkedHMM predict
696Phosphoserine(MAPK)HMM predict
696PhosphoserineHMM predict
696Phosphoserine(CDC2)HMM predict
734Phosphothreonine(MAPK)HMM predict
737Phosphothreonine(MAPK)HMM predict
801Phosphoserine(ATM)HMM predict
843Phosphoserine(CK1)HMM predict
846Phosphoserine(ATM)HMM predict
861Phosphoserine(ATM)HMM predict
915Phosphotyrosine(Syk)HMM predict
915Phosphotyrosine(EGFR)HMM predict
940Phosphotyrosine(INSR)HMM predict
964Phosphotyrosine(INSR)HMM predict
1030Phosphotyrosine(SRC)HMM predict
1030Phosphotyrosine(Syk)HMM predict
1155Phosphotyrosine(SRC)HMM predict
1193N-linkedHMM predict
1253Phosphotyrosine(INSR)HMM predict
1271O-linkedHMM predict
1368Phosphothreonine(MAPK)HMM predict
1438N-linkedHMM predict
1441N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_007050
  • Location:chr20 40134806-41251970
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF HelaGSE12889 41254066 41254297 231 2211
CTCF G2GSE9613 41253878 41254523 645 2230
KLF4 hESGSE17917 41263120 41263298 178 11239
hScc1 BcellGSE12603 41251301 41252790 1489 75
hScc1 BcellGSE12603 41254000 41254368 368 2214
hScc1 BcellGSE12603 41258365 41258626 261 6525
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 41249923 41250089 166 0
CTCF CD4SISSRdata 41249923 41250089 166 0
CTCF HelaGSE12889 41249933 41250200 267 0
CTCF JurkatGSE12889 40545775 40546033 258 0
CTCF G2GSE9613 40592765 40593244 479 0
CTCF G2GSE9613 41249642 41250518 876 0
FOXA1 MCF7GSE15244 40253355 40254266 911 0
FOXA1 MCF7GSE15244 40539460 40539856 396 0
FOXA1 eGFPGSE10845 40253355 40254266 911 0
FOXA1 eGFPGSE10845 40539460 40539856 396 0
FoxA1 MCF7MACSdata 40295898 40296050 152 0
FoxA1 MCF7MACSdata 40589368 40589626 258 0
H3K27me3 colorectalcancer 41250164 41250777 613 0
KLF4 hESGSE17917 40161505 40161665 160 0
KLF4 hESGSE17917 40490802 40491053 251 0
KLF4 hESGSE17917 41068753 41068918 165 0
KLF4 hESGSE17917 41250714 41251075 361 0
Myc K562GSE19551 40253679 40253971 292 0
Myc K562GSE19551 40545744 40546083 339 0
NFkBII GM12878GSE19485 40523437 40524835 1398 0
NRSF JurkatGSE13047 40187466 40187853 387 0
NRSF JurkatGSE13047 40241651 40242437 786 0
NRSF JurkatGSE13047 40750483 40751111 628 0
NRSF JurkatGSE13047 41102361 41103003 642 0
NRSF JurkatGSE13047 41105860 41106440 580 0
NRSF JurkatGSE13047 41249762 41250358 596 0
NRSF JurkatSISSRdata 40241728 40242338 610 0
NRSF JurkatSISSRdata 40750640 40750936 296 0
NRSF JurkatSISSRdata 41249762 41250201 439 0
NRSF mAbJurkat 40186659 40186859 200 0
NRSF mAbJurkat 40239361 40239835 474 0
NRSF mAbJurkat 40240305 40240477 172 0
NRSF mAbJurkat 40241216 40245532 4316 0
NRSF mAbJurkat 40246997 40248098 1101 0
NRSF mAbJurkat 40748018 40748301 283 0
NRSF mAbJurkat 40749143 40749903 760 0
NRSF mAbJurkat 40750790 40751041 251 0
NRSF mAbJurkat 41099281 41099928 647 0
NRSF mAbJurkat 41101288 41101713 425 0
NRSF mAbJurkat 41102161 41102962 801 0
NRSF mAbJurkat 41103382 41103742 360 0
NRSF mAbJurkat 41104226 41106582 2356 0
NRSF mAbJurkat 41247417 41247654 237 0
NRSF mAbJurkat 41248374 41250777 2403 0
NRSF-mono JurkatQuESTdata 40187465 40187910 445 0
NRSF-mono JurkatQuESTdata 40241683 40242467 784 0
NRSF-mono JurkatQuESTdata 40245255 40245482 227 0
NRSF-mono JurkatQuESTdata 40750474 40751110 636 0
NRSF-mono JurkatQuESTdata 41102360 41103002 642 0
NRSF-mono JurkatQuESTdata 41105865 41106433 568 0
NRSF-mono JurkatQuESTdata 41249761 41250357 596 0
NRSF-poly JurkatQuESTdata 40241784 40242305 521 0
NRSF-poly JurkatQuESTdata 40245227 40245627 400 0
NRSF-poly JurkatQuESTdata 40750692 40750951 259 0
NRSF-poly JurkatQuESTdata 41102355 41103053 698 0
NRSF-poly JurkatQuESTdata 41249763 41250591 828 0
Nanog ESGSE20650 40371041 40371609 568 0
Nanog hESGSE18292 40370912 40371545 633 0
Nanog hESGSE18292 41025741 41026153 412 0
Nanog hESGSE18292 41090473 41090957 484 0
Nanog hESGSE18292 41249804 41250003 199 0
Oct4 hESGSE17917 40161399 40161666 267 0
Oct4 hESGSE17917 40545743 40546046 303 0
RARA MCF7GSE15244 40253355 40255500 2145 0
Rb GrowingGSE19898 40242045 40242197 152 0
Rb GrowingGSE19898 40640026 40640185 159 0
STAT1 HeLaGSE12783 40369595 40370577 982 0
Sox2 hESGSE18292 40371147 40371565 418 0
TFAP2C MCF7GSE21234 40253235 40255590 2355 0
hScc1 BcellGSE12603 40292890 40293568 678 0
hScc1 BcellGSE12603 40412534 40412782 248 0
hScc1 BcellGSE12603 40427922 40428154 232 0
hScc1 BcellGSE12603 40592765 40593207 442 0
hScc1 BcellGSE12603 40632228 40632479 251 0
hScc1 BcellGSE12603 40738377 40738547 170 0
hScc1 BcellGSE12603 40839168 40839446 278 0
hScc1 BcellGSE12603 40871187 40871496 309 0
hScc1 BcellGSE12603 40988868 40989112 244 0
hScc1 BcellGSE12603 41005352 41005700 348 0
hScc1 BcellGSE12603 41200635 41201071 436 0
hScc1 BcellGSE12603 41223717 41223897 180 0
hScc1 BcellGSE12603 41249824 41250276 452 0
hScc1 CdLSGSE12603 41249376 41250311 935 0
hScc1 G2GSE9613 40592729 40593207 478 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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