AutismKB 2.0

Annotation Detail for CHGA


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Basic Information Top
Gene Symbol:CHGA ( CGA )
Gene Full Name: chromogranin A (parathyroid secretory protein 1)
Band: 14q32.12
Quick LinksEntrez ID:1113; OMIM: 118910; Uniprot ID:CMGA_HUMAN; ENSEMBL ID: ENSG00000100604; HGNC ID: 1929
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
112Phosphoserine.
113Phosphoserine.
136Phosphoserine.
142Phosphoserine.
181O-linked (GalNAc...).
183O-linked (GalNAc...).
203Phosphoserine.
218Phosphoserine.
251O-linked (GalNAc...).
270Phosphoserine.
300Phosphoserine.
319Glycine amide.
322Phosphoserine.
333Phosphoserine.
402Phosphoserine.
456Arginine amide.
Location(AA) Modifications Resource
0TOGlycBase6.0
0TOGlycBase6.0
0TOGlycBase6.0
112Phosphoserine.Swiss-Prot 53.0
113Phosphoserine.Swiss-Prot 53.0
136Phosphoserine.Swiss-Prot 53.0
142Phosphoserine.Swiss-Prot 53.0
181O-linked (GalNAc...)./FTId=CAR
183O-linked (GalNAc...)./FTId=CAR
203Phosphoserine.Swiss-Prot 53.0
218PhosphoserinePhospho.ELM 6.0
218Phosphoserine.Swiss-Prot 53.0
251O-linked (GalNAc...)./FTId=CAR
270Phosphoserine.Swiss-Prot 53.0
300Phosphoserine.Swiss-Prot 53.0
319Glycine amide (G-320 provides amidegroup).Swiss-Prot 53.0
322PhosphoserinePhospho.ELM 6.0
322Phosphoserine.Swiss-Prot 53.0
333PhosphoserinePhospho.ELM 6.0
333Phosphoserine.Swiss-Prot 53.0
402Phosphoserine.Swiss-Prot 53.0
456Arginine amide (G-457 provides amidegroup).Swiss-Prot 53.0
Location(AA) Modification Resource
45Phosphoserine(CK1)HMM predict
45Phosphoserine(IKK)HMM predict
48O-linkedHMM predict
68Phosphoserine(CK1)HMM predict
105Phosphoserine(CK2)HMM predict
105Phosphoserine(CK1)HMM predict
110N-linkedHMM predict
113Phosphoserine(ATM)HMM predict
113Phosphoserine(CK2)HMM predict
125Phosphoserine(CK1)HMM predict
136PhosphoserineHMM predict
136Phosphoserine(CK1)HMM predict
136Phosphoserine(CK2)HMM predict
161Phosphoserine(PKG)HMM predict
191Phosphoserine(ATM)HMM predict
300Phosphoserine(ATM)HMM predict
322PhosphoserineHMM predict
333Phosphoserine(CK1)HMM predict
392MethylarginineHMM predict
402Phosphoserine(CK1)HMM predict
436Phosphoserine(CK1)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001275
  • Location:chr14 92459244-92471388
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 92455463 92455662 199 3682
FOXA1 MCF7GSE15244 92452558 92453974 1416 5979
NRSF JurkatGSE13047 92449639 92450871 1232 8990
NRSF JurkatGSE13047 92450886 92452918 2032 7343
NRSF mAbJurkat 92441163 92441684 521 17821
NRSF mAbJurkat 92448874 92449549 675 10033
NRSF mAbJurkat 92450027 92450672 645 8895
NRSF mAbJurkat 92451028 92454813 3785 6324
NRSF mAbJurkat 92455203 92457216 2013 3035
NRSF mAbJurkat 92457799 92458901 1102 895
NRSF-mono JurkatQuESTdata 92448865 92449443 578 10091
NRSF-mono JurkatQuESTdata 92449781 92450734 953 8987
NRSF-mono JurkatQuESTdata 92450964 92451559 595 7983
NRSF-mono JurkatQuESTdata 92451565 92452672 1107 7126
NRSF-mono JurkatQuESTdata 92457855 92458337 482 1149
NRSF-poly JurkatQuESTdata 92448855 92449349 494 10143
NRSF-poly JurkatQuESTdata 92449629 92450854 1225 9003
NRSF-poly JurkatQuESTdata 92450933 92453481 2548 7038
NRSF-poly JurkatQuESTdata 92454550 92455868 1318 4036
RARA MCF7GSE15244 92452418 92453038 620 6517
RARA MCF7GSE15244 92453340 92453865 525 5642
RARA MCF7GSE15244 92455705 92456518 813 3133
RARG MCF7GSE15244 92452530 92453865 1335 6047
RARG MCF7GSE15244 92455627 92456518 891 3172
TFAP2C MCF7GSE21234 92453209 92454120 911 5580
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 92472206 92472670 464 1050
RARA MCF7GSE15244 92472903 92473853 950 1990
TFAP2C MCF7GSE21234 92472074 92472616 542 957
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 92459246 92459680 434 0
CTCF G2GSE9613 92465161 92465426 265 0
CTCF G2GSE9613 92467269 92467768 499 0
CTCF G2GSE9613 92468375 92468796 421 0
CTCF G2GSE9613 92470422 92471100 678 0
NRSF JurkatGSE13047 92457801 92461030 3229 0
NRSF mAbJurkat 92459680 92464074 4394 0
NRSF-mono JurkatQuESTdata 92458361 92461011 2650 0
NRSF-poly JurkatQuESTdata 92457801 92462327 4526 0
RARA MCF7GSE15244 92462647 92463832 1185 0
RARG MCF7GSE15244 92462046 92463760 1714 0
hScc1 BcellGSE12603 92459210 92459762 552 0
hScc1 BcellGSE12603 92464074 92464403 329 0
hScc1 BcellGSE12603 92467269 92467643 374 0
p63 keratinocytesGSE17611 92461743 92463300 1557 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018