AutismKB 2.0

Annotation Detail for CHGB


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Basic Information Top
Gene Symbol:CHGB ( SCG1 )
Gene Full Name: chromogranin B (secretogranin 1)
Band: 20p12.3
Quick LinksEntrez ID:1114; OMIM: 118920; Uniprot ID:SCG1_HUMAN; ENSEMBL ID: ENSG00000089199; HGNC ID: 1930
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
79Phosphothreonine (Probable).
99Phosphoserine (Potential).
100Phosphoserine (Potential).
116O-linked (GalNAc...) (Probable).
149Phosphoserine.
153N6-acetyllysine (By similarity).
182Phosphoserine.
183Phosphoserine.
259Phosphoserine.
263Phosphoserine.
293Phosphoserine (Potential).
294Phosphoserine (Potential).
311Phosphoserine.
335Phosphoserine.
341Sulfotyrosine (By similarity).
377Phosphoserine.
380Phosphoserine.
405Phosphoserine (Potential).
471Sulfotyrosine (Potential).
474Sulfotyrosine (Probable).
533Phosphoserine (Potential).
534Phosphoserine (Potential).
566Sulfotyrosine (Probable).
568Sulfotyrosine (Potential).
617Phosphoserine.
624Sulfotyrosine; partial (By similarity).
626Phosphoserine; partial.
631Phosphoserine (By similarity).
Location(AA) Modifications Resource
149Phosphoserine.Swiss-Prot 53.0
149PhosphoserinePhospho.ELM 6.0
153N6-acetyllysine (By similarity).Swiss-Prot 53.0
173Sulfotyrosine (Potential).Swiss-Prot 53.0
182Phosphoserine.Swiss-Prot 53.0
183Phosphoserine.Swiss-Prot 53.0
259Phosphoserine.Swiss-Prot 53.0
263Phosphoserine.Swiss-Prot 53.0
311Phosphoserine.Swiss-Prot 53.0
335Phosphoserine.Swiss-Prot 53.0
341Sulfotyrosine.Swiss-Prot 53.0
377Phosphoserine.Swiss-Prot 53.0
405Phosphoserine.Swiss-Prot 53.0
617Phosphoserine.Swiss-Prot 53.0
626Phosphoserine.Swiss-Prot 53.0
Location(AA) Modification Resource
46Phosphoserine(CK1)HMM predict
99Phosphoserine(CK1)HMM predict
100O-linkedHMM predict
100Phosphoserine(CK1)HMM predict
160Phosphoserine(ATM)HMM predict
160Phosphoserine(CK2)HMM predict
173Phosphotyrosine(INSR)HMM predict
175O-linkedHMM predict
182Phosphoserine(CK2)HMM predict
206Phosphoserine(PKA)HMM predict
225Phosphoserine(ATM)HMM predict
235Phosphoserine(IKK)HMM predict
236Phosphoserine(ATM)HMM predict
239Phosphoserine(CK2)HMM predict
245Phosphoserine(ATM)HMM predict
245Phosphoserine(CK2)HMM predict
245Phosphoserine(CK1)HMM predict
259Phosphoserine(IKK)HMM predict
259Phosphoserine(ATM)HMM predict
263Phosphoserine(CK1)HMM predict
263Phosphoserine(CK2)HMM predict
272Phosphoserine(CK1)HMM predict
279Phosphothreonine(PKC)HMM predict
294Phosphoserine(CK1)HMM predict
294Phosphoserine(IKK)HMM predict
298Phosphoserine(IKK)HMM predict
311Phosphoserine(IKK)HMM predict
311Phosphoserine(CK1)HMM predict
311Phosphoserine(CK2)HMM predict
314Phosphoserine(IKK)HMM predict
341SulfotyrosineHMM predict
341Phosphotyrosine(SRC)HMM predict
341Phosphotyrosine(INSR)HMM predict
341Phosphotyrosine(EGFR)HMM predict
370Phosphotyrosine(Syk)HMM predict
380Phosphoserine(CK2)HMM predict
389Phosphotyrosine(EGFR)HMM predict
405PhosphoserineHMM predict
474SulfotyrosineHMM predict
525Phosphotyrosine(Syk)HMM predict
526SulfotyrosineHMM predict
526Phosphotyrosine(Syk)HMM predict
568SulfotyrosineHMM predict
624SulfotyrosineHMM predict
624Phosphotyrosine(EGFR)HMM predict
649Phosphothreonine(CK2)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001819
  • Location:chr20 5840167-5854002
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
NRSF mAbJurkat 5838798 5839929 1131 804
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Myc K562GSE19551 5840071 5840496 425 0
NRSF JurkatGSE13047 5839576 5840970 1394 0
NRSF mAbJurkat 5840410 5841678 1268 0
NRSF mAbJurkat 5845088 5846446 1358 0
NRSF mAbJurkat 5847493 5847925 432 0
NRSF-mono JurkatQuESTdata 5839575 5840802 1227 0
NRSF-poly JurkatQuESTdata 5839655 5840886 1231 0
TAF HelaGSE8489 5847493 5847961 468 0
hScc1 BcellGSE12603 5839929 5840487 558 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018