AutismKB 2.0

Annotation Detail for NUDT6


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Basic Information Top
Gene Symbol:NUDT6 ( ASFGF2,FGF-2,FGF-AS,FGF2AS,bFGF,gfg,gfg-1 )
Gene Full Name: nudix (nucleoside diphosphate linked moiety X)-type motif 6
Band: 4q28.1
Quick LinksEntrez ID:11162; OMIM: 606261; Uniprot ID:NUDT6_HUMAN; ENSEMBL ID: ENSG00000170917; HGNC ID: 8053
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
197Nudix box.
Location(AA) Modifications Resource
76Glycyl lysine isopeptide (Lys-Gly)(interchain with G-Cter in ubiquitin).Swiss-Prot 53.0
Location(AA) Modification Resource
120Phosphoserine(CK1)HMM predict
122Phosphoserine(CK1)HMM predict
122Phosphoserine(IKK)HMM predict
123Phosphoserine(CK1)HMM predict
224Phosphotyrosine(Jak)HMM predict
243S-palmitoylHMM predict
259N-linkedHMM predict
261O-linkedHMM predict
309Phosphotyrosine(Syk)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_007083
  • Location:chr4 124033250-124063208
  • strand:-
No data
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 124054943 124055215 272 0
CTCF CD4SISSRdata 124054943 124055215 272 0
CTCF G2GSE9613 124054897 124055327 430 0
CTCF G2GSE9613 124062761 124063427 666 0
Oct1 HelaGSE14283 124052893 124052922 29 0
P300 T30-glioblastomaGSE21026 124038740 124039426 686 0
PHF8 HeLaGSE20725 124062620 124063674 1054 0
STAT1 HeLaGSE12782 124046828 124048281 1453 0
STAT1 HeLaGSE12783 124046828 124048227 1399 0
STAT1 IFNSISSRdata 124047291 124048033 742 0
Stat6 IL-4-hr1GSE17850 124044184 124044527 343 0
hScc1 BcellGSE12603 124054780 124055327 547 0
hScc1 BcellGSE12603 124062797 124063294 497 0
hScc1 CdLSGSE12603 124054677 124055511 834 0
hScc1 G2GSE9613 124054821 124055474 653 0
hScc1 G2GSE9613 124062761 124063427 666 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-15b hsa-mir-15b 3 20564181
hsa-miR-15b* hsa-mir-15b 3 20564181
hsa-miR-181b hsa-mir-181b-1 1 20564181
hsa-miR-181b hsa-mir-181b-2 9 20564181
hsa-miR-196a hsa-mir-196a-1 17 20480203
hsa-miR-196a hsa-mir-196a-2 12 20480203
hsa-miR-196a* hsa-mir-196a-2 12 20480203
hsa-miR-21 hsa-mir-21 17 21347332
hsa-miR-21* hsa-mir-21 17 21347332
No data
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
20164 mRNA FGF2 chr4 124105467 124176995 636 mRNA NUDT6 chr4 124171404 124201364Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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