AutismKB 2.0

Annotation Detail for LZTS1


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Basic Information Top
Gene Symbol:LZTS1 ( F37,FEZ1 )
Gene Full Name: leucine zipper, putative tumor suppressor 1
Band: 8p21.3
Quick LinksEntrez ID:11178; OMIM: 606551; Uniprot ID:LZTS1_HUMAN; ENSEMBL ID: ENSG00000061337; HGNC ID: 13861
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
47Phosphoserine(ATM)HMM predict
67Phosphotyrosine(Jak)HMM predict
67Phosphotyrosine(EGFR)HMM predict
178Phosphoserine(PKG)HMM predict
180O-linkedHMM predict
181O-linkedHMM predict
189Phosphoserine(CK1)HMM predict
212N-linkedHMM predict
233Phosphoserine(ATM)HMM predict
254Phosphoserine(CDC2)HMM predict
321Phosphoserine(CAMK2)HMM predict
324Phosphoserine(IKK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_021020
  • Location:chr8 20147956-20157082
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 20158579 20158819 240 1617
CTCF G2GSE9613 20162973 20163158 185 5983
Stat6 IL-4-hr1GSE17850 20167339 20167846 507 10510
hScc1 BcellGSE12603 20172864 20173002 138 15851
p63 keratinocytesGSE17611 20172295 20173432 1137 15781
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP JurkatGSE17954 20134664 20137341 2677 11954
CTCF G2GSE9613 20147426 20147781 355 353
NRSF pAbJurkat 20138088 20138449 361 9688
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 20148542 20149060 518 0
CTCF G2GSE9613 20150379 20150787 408 0
CTCF G2GSE9613 20151419 20151987 568 0
CTCF G2GSE9613 20155110 20155712 602 0
Oct1 H2O2-HelaGSE14283 20149361 20149389 28 0
Oct1 HelaGSE14283 20149361 20149389 28 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
25141 HTC chr8 20154252 20157851 1122 mRNA LZTS1 chr8 20147956 20157083Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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