AutismKB 2.0

Annotation Detail for PKP3


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Basic Information Top
Gene Symbol:PKP3 ( - )
Gene Full Name: plakophilin 3
Band: 11p15.5
Quick LinksEntrez ID:11187; OMIM: 605561; Uniprot ID:PKP3_HUMAN; ENSEMBL ID: ENSG00000184363; HGNC ID: 9025
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
84Phosphotyrosine.
115Phosphoserine.
176Phosphotyrosine.
180Phosphoserine.
195Phosphotyrosine.
238Phosphoserine.
240Phosphoserine.
313Phosphoserine.
314Phosphoserine.
390Phosphotyrosine.
Location(AA) Modifications Resource
84Phosphotyrosine.Swiss-Prot 53.0
84PhosphotyrosinePhospho.ELM 6.0
195Phosphotyrosine.Swiss-Prot 53.0
195PhosphotyrosinePhospho.ELM 6.0
238Phosphoserine.Swiss-Prot 53.0
238PhosphoserinePhospho.ELM 6.0
Location(AA) Modification Resource
95Phosphoserine(ATM)HMM predict
115O-linkedHMM predict
123O-linkedHMM predict
134Phosphoserine(CK1)HMM predict
134Phosphoserine(PKG)HMM predict
135Phosphoserine(PKB)HMM predict
176Phosphotyrosine(INSR)HMM predict
195Phosphotyrosine(Jak)HMM predict
196Phosphoserine(CK1)HMM predict
208Phosphoserine(PKC)HMM predict
209O-linkedHMM predict
220Phosphoserine(PKB)HMM predict
220Phosphoserine(CK2)HMM predict
220O-linkedHMM predict
220Phosphoserine(IKK)HMM predict
221Phosphoserine(CDC2)HMM predict
222Phosphoserine(CK1)HMM predict
223Phosphoserine(CK1)HMM predict
238Phosphoserine(CDC2)HMM predict
238Phosphoserine(MAPK)HMM predict
242Phosphothreonine(PKC)HMM predict
256Phosphoserine(CDK)HMM predict
285Phosphoserine(PKA)HMM predict
287Phosphoserine(IKK)HMM predict
308Phosphothreonine(CDK)HMM predict
382Phosphothreonine(PKA)HMM predict
422N-linkedHMM predict
429N-linkedHMM predict
454Phosphoserine(MAPK)HMM predict
454Phosphoserine(CDC2)HMM predict
454Phosphoserine(CDK)HMM predict
468N-linkedHMM predict
470Phosphoserine(CK2)HMM predict
477N-linkedHMM predict
484N-linkedHMM predict
539SulfotyrosineHMM predict
634N-linkedHMM predict
693Phosphoserine(CK1)HMM predict
711O-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_007183
  • Location:chr11 384216-394906
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
NRSF pAbJurkat 380517 381817 1300 3050
NRSF pAbJurkat 382400 382768 368 1633
NRSF pAbJurkat 383788 384203 415 221
TFAP2C MCF7GSE21234 383059 383730 671 822
TFAP2C MCF7GSE21234 383748 384287 539 199
hScc1 BcellGSE12603 380517 382043 1526 2937
p130 QuiescentGSE19898 383453 383867 414 557
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
NRSF pAbJurkat 394813 395682 869 341
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 387299 387500 201 0
CTCF CD4SISSRdata 387299 387500 201 0
ER Breast-CancerGSE22609 385962 386531 569 0
FOXA1 MCF7GSE15244 387720 387926 206 0
NRSF pAbJurkat 385582 386901 1319 0
NRSF pAbJurkat 389576 390737 1161 0
NRSF pAbJurkat 393855 394355 500 0
TFAP2C MCF7GSE21234 385719 386470 751 0
hScc1 BcellGSE12603 386541 387799 1258 0
hScc1 BcellGSE12603 393561 393961 400 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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