AutismKB 2.0

Annotation Detail for CHKB


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Basic Information Top
Gene Symbol:CHKB ( CHETK,CHKL,CK,CKB,CKEKB,EK,EKB )
Gene Full Name: choline kinase beta
Band: 22q13.33
Quick LinksEntrez ID:1120; OMIM: 612395; Uniprot ID:CHKB_HUMAN; ENSEMBL ID: ENSG00000100288; HGNC ID: 1938
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
2N-acetylalanine.
39Phosphoserine.
42Phosphoserine.
Location(AA) Modifications Resource
2N-acetylalanine.Swiss-Prot 53.0
Location(AA) Modification Resource
32Phosphothreonine(CDK)HMM predict
32Phosphothreonine(MAPK)HMM predict
32Phosphothreonine(CDC2)HMM predict
39Phosphoserine(PKG)HMM predict
39PhosphoserineHMM predict
40Phosphoserine(PKG)HMM predict
136Phosphotyrosine(Abl)HMM predict
234Phosphoserine(MAPK)HMM predict
327Phosphoserine(ATM)HMM predict
327Phosphoserine(CK1)HMM predict
378PhenylalanineHMM predict
380PhenylalanineHMM predict
381PhenylalanineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_005198
  • Location:chr22 49364252-49368259
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Fos K562GSE19551 49367990 49368591 601 31
p130 SenescentGSE19898 49368517 49368779 262 389
p130 shRbSenescentGSE19898 49368272 49368500 228 127
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3ac HepG2E 49367007 49367264 257 0
NFkBII GM15510GSE19485 49367267 49369044 1777 0
PHF8 HeLaGSE20725 49367182 49369110 1928 0
hScc1 BcellGSE12603 49367183 49368425 1242 0
p130 shRbSenescentGSE19898 49367799 49368111 312 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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