AutismKB 2.0

Annotation Detail for PROSC


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Basic Information Top
Gene Symbol:PROSC ( FLJ11861 )
Gene Full Name: proline synthetase co-transcribed homolog (bacterial)
Band: 8p11.2
Quick LinksEntrez ID:11212; OMIM: 604436; Uniprot ID:PROSC_HUMAN; ENSEMBL ID: ENSG00000147471; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
47N6-(pyridoxal phosphate)lysine (By
69Phosphotyrosine (By similarity).
244Phosphoserine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
69Phosphotyrosine(Abl)HMM predict
127N-linkedHMM predict
135Phosphoserine(CDC2)HMM predict
146N-linkedHMM predict
147Phosphothreonine(CK2)HMM predict
148Phosphoserine(CK2)HMM predict
191Phosphoserine(ATM)HMM predict
252Phosphotyrosine(EGFR)HMM predict
252Phosphotyrosine(Jak)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_007198
  • Location:chr8 37738832-37756442
  • strand:+
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 37756541 37756849 308 253
CTCF CD4SISSRdata 37756541 37756849 308 253
CTCF HelaGSE12889 37756605 37756754 149 237
CTCF G2GSE9613 37756477 37756797 320 195
CTCF G2GSE9613 37760615 37761683 1068 4707
GATA3 MCF7GSE15244 37762736 37763163 427 6507
Gata1 K562GSE18868 37762395 37763214 819 6362
Gata2 K562GSE18868 37762325 37763301 976 6371
RARG MCF7GSE15244 37762736 37763194 458 6523
Sox2 hESGSE18292 37756355 37756777 422 124
hScc1 BcellGSE12603 37756278 37756797 519 95
hScc1 CdLSGSE12603 37756278 37757121 843 257
hScc1 G2GSE9613 37756429 37756797 368 171
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 37739157 37739951 794 0
ETS1 JurkatGSE17954 37738635 37740061 1426 0
Fos K562GSE19551 37738905 37739524 619 0
GABP k562GSE8489 37738771 37739226 455 0
GABP k562GSE8489 37739748 37740710 962 0
H3K4me2 HCT116GSE10453 37740189 37740710 521 0
H3K4me3 colorectalcancer 37738771 37739050 279 0
H3K4me3 colorectalcancer 37739951 37740710 759 0
H3ac HepG2E 37739896 37740710 814 0
P300 T30-glioblastomaGSE21026 37738680 37740103 1423 0
PHF8 HeLaGSE20725 37738648 37740174 1526 0
PHF8 Hs68plusFBSGSE20725 37738723 37740046 1323 0
Rb GrowingGSE19898 37739019 37739155 136 0
Rb QuiescentGSE19898 37738955 37739328 373 0
Rb SenescentGSE19898 37738983 37739344 361 0
Rb shRbQuiescentGSE19898 37738889 37739293 404 0
TAF HelaGSE8489 37738771 37739298 527 0
TAF HelaGSE8489 37739701 37740710 1009 0
TAF k562GSE8489 37739785 37740710 925 0
hScc1 BcellGSE12603 37752705 37752836 131 0
p130 QuiescentGSE19898 37738829 37739173 344 0
p130 QuiescentGSE19898 37739216 37739445 229 0
p130 SenescentGSE19898 37738921 37739302 381 0
p130 shRbQuiescentGSE19898 37738784 37739386 602 0
p130 shRbSenescentGSE19898 37738772 37739550 778 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018