AutismKB 2.0

Annotation Detail for SEC63


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Basic Information Top
Gene Symbol:SEC63 ( ERdj2,PRO2507,SEC63L )
Gene Full Name: SEC63 homolog (S. cerevisiae)
Band: 6q21
Quick LinksEntrez ID:11231; OMIM: 608648; Uniprot ID:SEC63_HUMAN; ENSEMBL ID: ENSG00000025796; HGNC ID: 21082
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
307Phosphoserine (By similarity).
593Phosphoserine (By similarity).
597Phosphoserine (By similarity).
742Phosphoserine.
748Phosphoserine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
8SulfotyrosineHMM predict
11Phosphoserine(ATM)HMM predict
103Phosphotyrosine(Syk)HMM predict
106Phosphotyrosine(Syk)HMM predict
359Phosphothreonine(PKA)HMM predict
359Phosphothreonine(PKC)HMM predict
399Phosphoserine(PKG)HMM predict
432Phosphotyrosine(Syk)HMM predict
432Phosphotyrosine(EGFR)HMM predict
444Phosphotyrosine(Jak)HMM predict
461N-linkedHMM predict
507N-linkedHMM predict
523Phosphothreonine(PKC)HMM predict
526Phosphoserine(PKC)HMM predict
537Phosphothreonine(PKA)HMM predict
570Phosphoserine(CK1)HMM predict
570Phosphoserine(CK2)HMM predict
574Phosphoserine(CK2)HMM predict
576Phosphoserine(CK2)HMM predict
576PhosphoserineHMM predict
585Phosphoserine(ATM)HMM predict
587Phosphoserine(CK2)HMM predict
597Phosphoserine(CK2)HMM predict
597Phosphoserine(CK1)HMM predict
703Phosphotyrosine(INSR)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_007214
  • Location:chr6 108298215-108386085
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 108405211 108405377 166 19209
CTCF CD4SISSRdata 108405211 108405377 166 19209
H3ac HepG2E 108387375 108387565 190 1385
Rb GrowingGSE19898 108385929 108386323 394 41
Rb SenescentGSE19898 108385738 108386518 780 43
p130 SenescentGSE19898 108385750 108386510 760 45
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 108294923 108295172 249 3168
CTCF CD4SISSRdata 108294923 108295172 249 3168
CTCF G2GSE9613 108294924 108295471 547 3018
PolII HeLaGSE12783 108288077 108288493 416 9931
hScc1 G2GSE9613 108294924 108295320 396 3094
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 108385299 108386458 1159 0
ER E2-MCF7GSE14664 108365022 108365152 130 0
ER Fulvestrant-MCF7GSE14664 108365056 108365131 75 0
FoxA1 MCF7MACSdata 108308321 108308566 245 0
H3K4me2 HCT116GSE10453 108384716 108385335 619 0
H3K4me3 colorectalcancer 108384247 108385673 1426 0
H3ac HepG2E 108379945 108380134 189 0
H3ac HepG2E 108382647 108382928 281 0
H3ac HepG2E 108384036 108385525 1489 0
Oct1 H2O2-HelaGSE14283 108368565 108368591 26 0
Oct1 HelaGSE14283 108333751 108333785 34 0
Oct1 HelaGSE14283 108368519 108368594 75 0
PHF8 Hs68plusFBSGSE20725 108384624 108386465 1841 0
RARA MCF7GSE15244 108307799 108308902 1103 0
TAF HelaGSE8489 108384112 108385491 1379 0
TAF k562GSE8489 108384036 108385673 1637 0
hScc1 BcellGSE12603 108385706 108386160 454 0
p130 QuiescentGSE19898 108385751 108385955 204 0
p130 SenescentGSE19898 108384608 108384818 210 0
p130 shRbQuiescentGSE19898 108385755 108386285 530 0
p130 shRbSenescentGSE19898 108385768 108386289 521 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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