AutismKB 2.0

Annotation Detail for CHRM1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:CHRM1 ( HM1,M1,M1R,MGC30125 )
Gene Full Name: cholinergic receptor, muscarinic 1
Band: 11q12.3
Quick LinksEntrez ID:1128; OMIM: 118510; Uniprot ID:ACM1_HUMAN; ENSEMBL ID: ENSG00000168539; HGNC ID: 1950
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
2N-linked (GlcNAc...) (Probable).
12N-linked (GlcNAc...) (Probable).
428Phosphothreonine (Potential).
451Phosphoserine (Potential).
455Phosphothreonine (Potential).
457Phosphoserine (Potential).
Location(AA) Modifications Resource
2N-linked (GlcNAc...) (Probable).Swiss-Prot 53.0
12N-linked (GlcNAc...) (Probable).Swiss-Prot 53.0
428Phosphothreonine (Potential).Swiss-Prot 53.0
451Phosphoserine (Potential).Swiss-Prot 53.0
455Phosphothreonine (Potential).Swiss-Prot 53.0
457Phosphoserine (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
12N-linkedHMM predict
138Phosphothreonine(CDK)HMM predict
138Phosphothreonine(MAPK)HMM predict
138Phosphothreonine(CDC2)HMM predict
184Phosphoserine(ATM)HMM predict
237O-linkedHMM predict
244Phosphoserine(CK1)HMM predict
244Phosphoserine(ATM)HMM predict
251O-linkedHMM predict
251Phosphoserine(IKK)HMM predict
254Phosphothreonine(MAPK)HMM predict
254Phosphothreonine(CDC2)HMM predict
254Phosphothreonine(CDK)HMM predict
284Phosphoserine(CK1)HMM predict
290Phosphoserine(CK1)HMM predict
290Phosphoserine(CK2)HMM predict
325Phosphothreonine(PKC)HMM predict
330Phosphothreonine(PKC)HMM predict
330Phosphothreonine(PKA)HMM predict
366Phosphothreonine(PKC)HMM predict
410N-linkedHMM predict
414N-linkedHMM predict
455Phosphothreonine(CDC2)HMM predict
455Phosphothreonine(MAPK)HMM predict
455Phosphothreonine(CDK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_000738
  • Location:chr11 62432727-62445587
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 62447207 62447452 245 1742
CTCF CD4SISSRdata 62447207 62447452 245 1742
ER E2-MCF7GSE14664 62448355 62448389 34 2785
ER Fulvestrant-MCF7GSE14664 62448356 62448390 34 2786
H3K27me3 colorectalcancer 62450826 62452011 1185 5831
NRSF pAbJurkat 62445415 62446005 590 123
NRSF pAbJurkat 62446533 62447139 606 1249
Oct1 H2O2-HelaGSE14283 62448358 62448387 29 2785
Oct1 H2O2-HelaGSE14283 62462122 62462155 33 16551
Oct1 HelaGSE14283 62448356 62448404 48 2793
Oct1 HelaGSE14283 62462104 62462163 59 16546
p130 SenescentGSE19898 62450345 62450636 291 4903
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 62430065 62430448 383 2471
CTCF CD4SISSRdata 62430065 62430448 383 2471
RARG MCF7GSE15244 62429670 62430044 374 2871
hScc1 BcellGSE12603 62429870 62430747 877 2419
hScc1 CdLSGSE12603 62429782 62430502 720 2586
hScc1 G2GSE9613 62429983 62430477 494 2498
p130 SenescentGSE19898 62427322 62427536 214 5299
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
NRSF pAbJurkat 62443483 62443769 286 0
Oct1 H2O2-HelaGSE14283 62433334 62433364 30 0
Oct1 HelaGSE14283 62433334 62433366 32 0
Oct1 HelaGSE14283 62442120 62442155 35 0
TFAP2C MCF7GSE21234 62433247 62433691 444 0
hScc1 BcellGSE12603 62433124 62433475 351 0
hScc1 G2GSE9613 62432979 62433727 748 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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