AutismKB 2.0

Annotation Detail for CHRM2


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Basic Information Top
Gene Symbol:CHRM2 ( FLJ43243,HM2,MGC120006,MGC120007 )
Gene Full Name: cholinergic receptor, muscarinic 2
Band: 7q33
Quick LinksEntrez ID:1129; OMIM: 118493; Uniprot ID:ACM2_HUMAN; ENSEMBL ID: ENSG00000181072; HGNC ID: 1951
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
2N-linked (GlcNAc...) (Potential).
3N-linked (GlcNAc...) (Potential).
6N-linked (GlcNAc...) (Potential).
9N-linked (GlcNAc...) (Potential).
232Phosphoserine (By similarity).
234Phosphoserine (By similarity).
446Phosphothreonine (Potential).
450Phosphothreonine (Potential).
465Phosphothreonine (Potential).
Location(AA) Modifications Resource
2N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
3N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
6N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
9N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
232Phosphoserine (By similarity).Swiss-Prot 53.0
232Phosphoserine (GRK
234Phosphoserine (GRK
234Phosphoserine (By similarity).Swiss-Prot 53.0
250Phosphoserine (GRK
251Phosphoserine (GRK
271Phosphothreonine (GRK
282Phosphoserine (GRK
283Phosphoserine (GRK
286Phosphoserine (GRK
287Phosphothreonine (GRK
288Phosphoserine (GRK
290Phosphoserine (GRK
294Phosphoserine (GRK
302Phosphothreonine (GRK
307Phosphothreonine (GRK
309Phosphoserine (GRK
310Phosphothreonine (GRK
311Phosphoserine (GRK
446Phosphothreonine (Potential).Swiss-Prot 53.0
450Phosphothreonine (Potential).Swiss-Prot 53.0
465Phosphothreonine (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
9N-linkedHMM predict
10N-linkedHMM predict
16Phosphoserine(CDC2)HMM predict
16Phosphoserine(CDK)HMM predict
18Phosphotyrosine(Syk)HMM predict
137Phosphothreonine(PKA)HMM predict
137Phosphothreonine(PKC)HMM predict
190O-linkedHMM predict
232Phosphoserine(MAPK)HMM predict
283Phosphoserine(IKK)HMM predict
284N-linkedHMM predict
286O-linkedHMM predict
287O-linkedHMM predict
288Phosphoserine(CK1)HMM predict
288O-linkedHMM predict
302Phosphothreonine(CK2)HMM predict
310PhosphothreonineHMM predict
331Phosphothreonine(CDC2)HMM predict
331Phosphothreonine(CDK)HMM predict
334O-linkedHMM predict
336Phosphoserine(IKK)HMM predict
338Phosphothreonine(MAPK)HMM predict
338Phosphothreonine(CDC2)HMM predict
340O-linkedHMM predict
341N-linkedHMM predict
342O-linkedHMM predict
432N-linkedHMM predict
436N-linkedHMM predict
444N-linkedHMM predict
461AsparagineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001006627
  • Location:chr7 136203938-136352310
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
NRSF JurkatGSE13047 136192663 136193619 956 10798
NRSF mAbJurkat 136190865 136193288 2423 11862
NRSF mAbJurkat 136194175 136195603 1428 9050
NRSF-mono JurkatQuESTdata 136192715 136193585 870 10789
NRSF pAbJurkat 136192691 136193105 414 11041
NRSF-poly JurkatQuESTdata 136192695 136193310 615 10936
P300 T30-glioblastomaGSE21026 136192734 136193466 732 10839
No data
No data
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
24691 mRNA CHRM2 chr7 136010653 136159026 118252 mRNA LOC349160 chr7 136040774 136306343 Non-exonic Bidirectional (NOB) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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