AutismKB 2.0

Annotation Detail for CHRM3


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Basic Information Top
Gene Symbol:CHRM3 ( HM3 )
Gene Full Name: cholinergic receptor, muscarinic 3
Band: 1q43
Quick LinksEntrez ID:1131; OMIM: 118494; Uniprot ID:ACM3_HUMAN; ENSEMBL ID: ENSG00000133019; HGNC ID: 1952
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
5N-linked (GlcNAc...) (Potential).
6N-linked (GlcNAc...) (Potential).
15N-linked (GlcNAc...) (Potential).
41N-linked (GlcNAc...) (Potential).
48N-linked (GlcNAc...) (Potential).
281Basolateral sorting signal.
Location(AA) Modifications Resource
5N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
6N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
15N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
41N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
48N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
8O-linkedHMM predict
10Phosphoserine(CDK)HMM predict
10Phosphoserine(CDC2)HMM predict
15N-linkedHMM predict
48N-linkedHMM predict
51Phosphoserine(CDK)HMM predict
51Phosphoserine(CDC2)HMM predict
175Phosphothreonine(PKC)HMM predict
181Phosphothreonine(PKC)HMM predict
182Phosphothreonine(PKC)HMM predict
235O-linkedHMM predict
332Phosphoserine(IKK)HMM predict
333Phosphoserine(CK1)HMM predict
334Phosphoserine(CK1)HMM predict
336Phosphoserine(IKK)HMM predict
351Phosphoserine(CK2)HMM predict
351Phosphoserine(CK2)HMM predict
352Phosphoserine(CK2)HMM predict
352Phosphoserine(CK2)HMM predict
352Phosphoserine(CK1)HMM predict
359Phosphoserine(CK1)HMM predict
379N-linkedHMM predict
492Phosphothreonine(PKC)HMM predict
536N-linkedHMM predict
540N-linkedHMM predict
548N-linkedHMM predict
561S-palmitoylHMM predict
563S-palmitoylHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_000740
  • Location:chr1 237858995-238139337
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
SRF GMOGSE8489 237843469 237843770 301 15376
SRF HepG2GSE8489 237843390 237843770 380 15416
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 238128139 238128432 293 0
CTCF CD4SISSRdata 238128139 238128432 293 0
CTCF G2GSE9613 237883711 237883849 138 0
CTCF G2GSE9613 238047558 238047738 180 0
CTCF G2GSE9613 238098970 238099291 321 0
CTCF G2GSE9613 238127959 238128575 616 0
CTCF G2GSE9613 238138222 238138533 311 0
Nanog hESGSE18292 238118547 238119038 491 0
SRF GMOGSE8489 237941182 237941861 679 0
SRF HepG2GSE8489 237904821 237905053 232 0
Stat6 IL-4-hr4GSE17850 237974657 237975181 524 0
TFAP2C MCF7GSE21234 238044211 238044662 451 0
TFAP2C MCF7GSE21234 238109125 238109727 602 0
hScc1 BcellGSE12603 238127959 238128539 580 0
hScc1 BcellGSE12603 238129671 238129977 306 0
hScc1 CdLSGSE12603 238127857 238128782 925 0
hScc1 G2GSE9613 238127722 238128615 893 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
2578 mRNA CHRM3 chr1 236118413 236398756 15175 HTC chr1 236193232 236208407 Non-exonic Bidirectional (NOB) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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