Annotation Detail for CASC4

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Basic Information Top

Gene Symbol:	CASC4 ( DKFZp459F1927,H63,MGC74708 )
Gene Full Name:	cancer susceptibility candidate 4
Band:	15q15.3
Quick Links	Entrez ID:113201; OMIM: NA; Uniprot ID:CASC4_HUMAN; ENSEMBL ID: ENSG00000166734; HGNC ID: 24892
Relate to Another Database:	SFARIGene; denovo-db

Pathways, Diseases and Drugs

TF binding site

Post Translation Modification

PTM Sites from Uniprot:1 results
Experimental PTM Sites from dbPTM:0 results
Predicted PTM Sites by profile HMM from dbPTM:0 results

Location(AA)	Modification
366	Phosphoserine (By similarity).

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

RefSeq ID: NM_138423
Location:chr15 42368220-42495246
strand:+

Upstream the gene:7 results
Downstream the gene:0 results
Inside the gene:14 results

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
ETS1	Jurkat	GSE17954	42367277	42368646	1369	259
H3K4me3	colorectal	cancer	42367082	42367884	802	738
H3ac	HepG2	E	42366748	42367884	1136	905
P300	T30-glioblastoma	GSE21026	42367326	42368566	1240	275
hScc1	Bcell	GSE12603	42367679	42368116	437	323
p130	Quiescent	GSE19898	42367270	42367558	288	807
p130	shRbSenescent	GSE19898	42367591	42368049	458	401

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
Fos	K562	GSE19551	42376242	42377036	794	0
H3K4me3	colorectal	cancer	42368934	42369540	606	0
H3ac	HepG2	E	42368738	42369222	484	0
Nanog	ES	GSE20650	42405129	42405482	353	0
Nanog	hES	GSE18292	42469779	42470097	318	0
Oct1	H2O2-Hela	GSE14283	42401273	42401302	29	0
Oct1	H2O2-Hela	GSE14283	42415618	42415661	43	0
Oct1	Hela	GSE14283	42398113	42398153	40	0
Oct1	Hela	GSE14283	42401273	42401302	29	0
Oct1	Hela	GSE14283	42415619	42415673	54	0
P300	T0-glioblastoma	GSE21026	42464332	42465236	904	0
P300	T30-glioblastoma	GSE21026	42419831	42420272	441	0
Sox2	hES	GSE18292	42405160	42405411	251	0
TFAP2C	MCF7	GSE21234	42378412	42378685	273	0

Validated miRNA targets

Cis-Nats regulation

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

Studies: 1,036
Genes: 1,379
CNVs/SVs: 5,420
SNVs/Indels: 11,669
de novo Mutations: 5,669
Mosaics: 789
Linkage Regions: 172

Paper Collected: 6/30/2018

Last Update: 8/26/2018

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