AutismKB 2.0

Annotation Detail for DDX42


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Basic Information Top
Gene Symbol:DDX42 ( FLJ43179,RHELP,RNAHP,SF3b125 )
Gene Full Name: DEAD (Asp-Glu-Ala-Asp) box polypeptide 42
Band: 17q23.3
Quick LinksEntrez ID:11325; OMIM: 613369; Uniprot ID:DDX42_HUMAN; ENSEMBL ID: ENSG00000198231; HGNC ID: 18676
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
5N6-acetyllysine.
10Phosphothreonine.
96Phosphoserine.
104Phosphoserine.
109Phosphoserine.
111Phosphoserine.
185Phosphoserine.
281Q motif.
410DEAD box.
751Phosphoserine.
754Phosphoserine.
Location(AA) Modifications Resource
10Phosphothreonine.Swiss-Prot 53.0
10PhosphothreoninePhospho.ELM 6.0
96Phosphoserine.Swiss-Prot 53.0
96PhosphoserinePhospho.ELM 6.0
109Phosphoserine.Swiss-Prot 53.0
109PhosphoserinePhospho.ELM 6.0
111PhosphoserinePhospho.ELM 6.0
111Phosphoserine.Swiss-Prot 53.0
185Phosphoserine (By similarity).Swiss-Prot 53.0
185PhosphoserinePhospho.ELM 6.0
751PhosphoserinePhospho.ELM 6.0
754PhosphoserinePhospho.ELM 6.0
Location(AA) Modification Resource
42O-linkedHMM predict
46O-linkedHMM predict
75SulfotyrosineHMM predict
83Phosphoserine(CK1)HMM predict
90Phosphotyrosine(Jak)HMM predict
167N-linkedHMM predict
183SulfotyrosineHMM predict
210SulfotyrosineHMM predict
218Phosphotyrosine(EGFR)HMM predict
218Phosphotyrosine(Syk)HMM predict
226N-linkedHMM predict
244O-linkedHMM predict
383Phosphothreonine(CDC2)HMM predict
715Phosphoserine(PKG)HMM predict
751Phosphoserine(ATM)HMM predict
751Phosphoserine(CDK)HMM predict
751Phosphoserine(CDC2)HMM predict
754Phosphoserine(IKK)HMM predict
754Phosphoserine(CDC2)HMM predict
771N-linkedHMM predict
781O-linkedHMM predict
788N-linkedHMM predict
789N-linkedHMM predict
794N-linkedHMM predict
795N-linkedHMM predict
844Phosphotyrosine(INSR)HMM predict
844Phosphotyrosine(EGFR)HMM predict
850O-linkedHMM predict
850Phosphoserine(CK1)HMM predict
875MethylarginineHMM predict
934Phosphoserine(PKA)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_007372
  • Location:chr17 59205298-59250407
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3ac HepG2E 59204827 59205240 413 265
P300 T30-glioblastomaGSE21026 59203715 59206335 2620 274
PHF8 HeLaGSE20725 59204265 59205936 1671 198
PHF8 Hs68minusFBSGSE20725 59203982 59206001 2019 307
PHF8 Hs68plusFBSGSE20725 59203980 59206020 2040 299
USF1 HepG2E 59204719 59205430 711 224
USF2 HepG2E 59204783 59205268 485 273
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 59248863 59249188 325 0
H3K4me2 HCT116GSE10453 59205836 59206933 1097 0
H3K4me3 colorectalcancer 59205738 59207147 1409 0
H3ac HepG2E 59205621 59207580 1959 0
H3ac HepG2E 59208842 59209708 866 0
STAT1 IFNSISSRdata 59249731 59250447 716 0
TAF k562GSE8489 59205942 59206723 781 0
p63 keratinocytesGSE17611 59223369 59223889 520 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018