AutismKB 2.0

Annotation Detail for U2AF2


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:U2AF2 ( U2AF65 )
Gene Full Name: U2 small nuclear RNA auxiliary factor 2
Band: 19q13.43
Quick LinksEntrez ID:11338; OMIM: 191318; Uniprot ID:U2AF2_HUMAN; ENSEMBL ID: ENSG00000063244; HGNC ID: 23156
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
2N-acetylserine.
2Phosphoserine.
155-hydroxylysine; by JMJD6.
53Phosphoserine.
55Phosphoserine.
70N6-acetyllysine.
79Phosphoserine.
2765-hydroxylysine; by JMJD6.
462N6-acetyllysine.
Location(AA) Modifications Resource
1PhosphoserinePhospho.ELM 6.0
2N-acetylserine.Swiss-Prot 53.0
2Phosphoserine.Swiss-Prot 53.0
52PhosphoserinePhospho.ELM 6.0
53Phosphoserine.Swiss-Prot 53.0
54PhosphoserinePhospho.ELM 6.0
55Phosphoserine.Swiss-Prot 53.0
61PhosphoserinePhospho.ELM 6.0
78PhosphoserinePhospho.ELM 6.0
79Phosphoserine.Swiss-Prot 53.0
Location(AA) Modification Resource
28Phosphoserine(PKG)HMM predict
62Phosphoserine(PKG)HMM predict
62Phosphoserine(PKB)HMM predict
62Phosphoserine(PKA)HMM predict
66Phosphothreonine(PKC)HMM predict
124O-linkedHMM predict
126PhosphothreonineHMM predict
133Phosphothreonine(MAPK)HMM predict
133O-linkedHMM predict
135Phosphothreonine(MAPK)HMM predict
232Phosphotyrosine(Syk)HMM predict
241N-linkedHMM predict
251O-linkedHMM predict
311N-linkedHMM predict
341N-linkedHMM predict
346Phosphoserine(IKK)HMM predict
349O-linkedHMM predict
352N-linkedHMM predict
366Phosphoserine(ATM)HMM predict
395Phosphotyrosine(Syk)HMM predict
395Phosphotyrosine(INSR)HMM predict
395Phosphotyrosine(EGFR)HMM predict
395SulfotyrosineHMM predict
458ValineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001012478
  • Location:chr19 60857227-60877892
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 60856818 60857248 430 195
CTCF CD4SISSRdata 60856818 60857248 430 195
CTCF HelaGSE12889 60856801 60857149 348 253
CTCF JurkatGSE12889 60856847 60857204 357 202
CTCF G2GSE9613 60856866 60857433 567 78
HIF1 NormHepG2 60856866 60857433 567 78
Rb GrowingGSE19898 60856853 60857109 256 247
hScc1 BcellGSE12603 60856866 60857471 605 59
p130 SenescentGSE19898 60856816 60857517 701 61
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 60874812 60874977 165 0
CTCF CD4SISSRdata 60874812 60874977 165 0
CTCF HelaGSE12889 60874820 60875020 200 0
ER E2-MCF7GSE14664 60867396 60867437 41 0
ETS1 JurkatGSE17954 60856770 60859112 2342 0
GABP k562GSE8489 60858912 60859742 830 0
GABP k562GSE8489 60860292 60860438 146 0
GABP k562GSE8489 60868241 60868781 540 0
GABP k562GSE8489 60876678 60877078 400 0
H3K4me3 colorectalcancer 60859056 60859720 664 0
H3ac HepG2E 60858949 60859742 793 0
H3ac HepG2E 60860292 60861660 1368 0
Oct1 HelaGSE14283 60857670 60857701 31 0
PHF8 HeLaGSE20725 60856595 60859088 2493 0
RUNX JurkatGSE17954 60873610 60873731 121 0
SRF GMOGSE8489 60865016 60865667 651 0
SRF k562GSE8489 60868341 60868781 440 0
TAF HelaGSE8489 60859096 60859540 444 0
TAF HelaGSE8489 60868276 60868781 505 0
TAF k562GSE8489 60859019 60859742 723 0
TAF k562GSE8489 60868241 60868781 540 0
p130 shRbQuiescentGSE19898 60857215 60857925 710 0
p130 shRbQuiescentGSE19898 60858183 60858450 267 0
p130 shRbSenescentGSE19898 60856863 60857610 747 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved