AutismKB 2.0

Annotation Detail for CHRNA3


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Basic Information Top
Gene Symbol:CHRNA3 ( LNCR2,MGC104879,NACHRA3,PAOD2 )
Gene Full Name: cholinergic receptor, nicotinic, alpha 3
Band: 15q25.1
Quick LinksEntrez ID:1136; OMIM: 118503; Uniprot ID:ACHA3_HUMAN; ENSEMBL ID: ENSG00000080644; HGNC ID: 1957
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
55N-linked (GlcNAc...) (Potential).
172N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
53N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
170N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
219PhosphotyrosinePhospho.ELM 6.0
226PhosphotyrosinePhospho.ELM 6.0
Location(AA) Modification Resource
12Phosphoserine(CDC2)HMM predict
12PhosphoserineHMM predict
53N-linkedHMM predict
67Phosphoserine(ATM)HMM predict
97N-linkedHMM predict
101Phosphotyrosine(INSR)HMM predict
226Phosphotyrosine(EGFR)HMM predict
330Phosphothreonine(MAPK)HMM predict
359Phosphoserine(IKK)HMM predict
403S-palmitoylHMM predict
416N-linkedHMM predict
421Phosphoserine(PKA)HMM predict
422Phosphoserine(CK1)HMM predict
425Phosphoserine(IKK)HMM predict
425Phosphoserine(CK1)HMM predict
436Phosphoserine(MAPK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_000743
  • Location:chr15 76674706-76700376
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP JurkatGSE17954 76700445 76702213 1768 953
H3K27me3 colorectalcancer 76701662 76701897 235 1403
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 76697900 76698137 237 0
CTCF CD4SISSRdata 76697900 76698137 237 0
CTCF G2GSE9613 76697684 76698362 678 0
CTCF G2GSE9613 76699608 76700348 740 0
ER MCF7GSE19013 76681495 76681951 456 0
Oct1 HelaGSE14283 76687205 76687240 35 0
RNAII Tamoxifen-MCF7GSE14664 76697493 76697595 102 0
RUNX JurkatGSE17954 76685015 76685097 82 0
hScc1 BcellGSE12603 76697653 76698505 852 0
hScc1 BcellGSE12603 76699304 76700525 1221 0
hScc1 CdLSGSE12603 76697653 76698439 786 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
9138 mRNA CHRNA5 chr15 76644960 76673513 198 mRNA CHRNA3 chr15 76672449 76676129Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018