AutismKB 2.0

Annotation Detail for CHRNA4


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Basic Information Top
Gene Symbol:CHRNA4 ( BFNC,EBN,EBN1,FLJ95812,NACHR,NACHRA4,NACRA4 )
Gene Full Name: cholinergic receptor, nicotinic, alpha 4
Band: 20q13.33
Quick LinksEntrez ID:1137; OMIM: 118504; Uniprot ID:ACHA4_HUMAN; ENSEMBL ID: ENSG00000101204; HGNC ID: 1958
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
57N-linked (GlcNAc...) (Potential).
107N-linked (GlcNAc...) (Potential).
174N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
57N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
107N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
174N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
105Phosphotyrosine(Syk)HMM predict
107N-linkedHMM predict
396O-linkedHMM predict
396O-linkedHMM predict
398O-linkedHMM predict
405O-linkedHMM predict
424Phosphoserine(IKK)HMM predict
424Phosphoserine(CDC2)HMM predict
445Phosphoserine(CDK)HMM predict
445O-linkedHMM predict
465Phosphoserine(CK1)HMM predict
467Phosphoserine(ATM)HMM predict
517O-linkedHMM predict
527Phosphoserine(IKK)HMM predict
538O-linkedHMM predict
539O-linkedHMM predict
539Phosphoserine(ATM)HMM predict
539Phosphoserine(IKK)HMM predict
541Phosphoserine(CDC2)HMM predict
541Phosphoserine(IKK)HMM predict
545Phosphothreonine(PKC)HMM predict
545O-linkedHMM predict
545O-linkedHMM predict
551Phosphothreonine(PKA)HMM predict
627IsoleucineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_000744
  • Location:chr20 61445108-61463191
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 61470669 61471291 622 7789
CTCF G2GSE9613 61473430 61474270 840 10659
CTCF G2GSE9613 61475018 61475700 682 12168
NRSF JurkatGSE13047 61480358 61481216 858 17596
NRSF mAbJurkat 61479361 61481073 1712 17026
NRSF-mono JurkatQuESTdata 61480363 61481256 893 17618
NRSF-poly JurkatQuESTdata 61480275 61481740 1465 17816
TFAP2C MCF7GSE21234 61474749 61475122 373 11744
hScc1 BcellGSE12603 61467361 61468116 755 4547
hScc1 BcellGSE12603 61471844 61472365 521 8913
hScc1 BcellGSE12603 61473319 61473675 356 10306
hScc1 BcellGSE12603 61473917 61474411 494 10973
hScc1 BcellGSE12603 61474849 61476313 1464 12390
hScc1 BcellGSE12603 61477226 61477698 472 14271
hScc1 BcellGSE12603 61479187 61479891 704 16348
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
GABP k562GSE8489 61441287 61442450 1163 3240
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 61448383 61448735 352 0
CTCF G2GSE9613 61450255 61451390 1135 0
CTCF G2GSE9613 61454653 61455038 385 0
TFAP2C MCF7GSE21234 61456535 61457340 805 0
hScc1 BcellGSE12603 61448347 61448773 426 0
hScc1 BcellGSE12603 61449264 61451648 2384 0
hScc1 BcellGSE12603 61454700 61455197 497 0
hScc1 BcellGSE12603 61459647 61460784 1137 0
hScc1 BcellGSE12603 61461347 61463280 1933 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-1 hsa-mir-1-2 18 18510933
hsa-miR-1 hsa-mir-1-1 20 18510933
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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