AutismKB 2.0

Annotation Detail for CHRNA7


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Basic Information Top
Gene Symbol:CHRNA7 ( CHRNA7-2,NACHRA7 )
Gene Full Name: cholinergic receptor, nicotinic, alpha 7
Band: 15q13.3
Quick LinksEntrez ID:1139; OMIM: 118511; Uniprot ID:ACHA7_HUMAN; ENSEMBL ID: ENSG00000175344; HGNC ID: 1960
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
46N-linked (GlcNAc...) (Potential).
90N-linked (GlcNAc...) (Potential).
133N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
46N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
90N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
133N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
386Phosphotyrosine (Src)Phospho.ELM 6.0
442Phosphotyrosine (Src)Phospho.ELM 6.0
Location(AA) Modification Resource
46N-linkedHMM predict
90N-linkedHMM predict
99Phosphothreonine(PKC)HMM predict
133N-linkedHMM predict
140Phosphotyrosine(Jak)HMM predict
140Phosphotyrosine(Syk)HMM predict
190Phosphotyrosine(INSR)HMM predict
230Phosphothreonine(PKA)HMM predict
365Phosphoserine(PKG)HMM predict
365Phosphoserine(PKA)HMM predict
372Phosphoserine(IKK)HMM predict
380O-linkedHMM predict
413Phosphoserine(ATM)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_000746
  • Location:chr15 30110017-30248524
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 30109726 30110063 337 123
Oct1 HelaGSE14283 30107865 30107893 28 2139
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 30261060 30261388 328 12700
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 30200161 30200534 373 0
CTCF G2GSE9613 30233164 30233782 618 0
Oct1 H2O2-HelaGSE14283 30215098 30215124 26 0
Oct1 H2O2-HelaGSE14283 30248002 30248041 39 0
Oct1 HelaGSE14283 30248003 30248041 38 0
PHF8 293TGSE20725 30109666 30110526 860 0
RNAII Tamoxifen-MCF7GSE14664 30244691 30244773 82 0
RNAII Tamoxifen-MCF7GSE14664 30248001 30248037 36 0
Stat6 IL-4-hr4GSE17850 30196104 30196677 573 0
hScc1 BcellGSE12603 30140414 30140592 178 0
hScc1 BcellGSE12603 30242101 30242583 482 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
8590 mRNA CHRNA7 chr15 30110017 30248525 107 EST chr15 30236875 30244641Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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