AutismKB 2.0

Annotation Detail for ADCY8


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Basic Information Top
Gene Symbol:ADCY8 ( AC8,ADCY3,HBAC1 )
Gene Full Name: adenylate cyclase 8 (brain)
Band: 8q24.22
Quick LinksEntrez ID:114; OMIM: 103070; Uniprot ID:ADCY8_HUMAN; ENSEMBL ID: ENSG00000155897; HGNC ID: 239
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
817N-linked (GlcNAc...) (Potential).
821N-linked (GlcNAc...) (Potential).
888N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
817N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
821N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
888N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
31Phosphoserine(PKA)HMM predict
62Phosphoserine(ATM)HMM predict
102Phosphoserine(IKK)HMM predict
115Phosphoserine(IKK)HMM predict
115Phosphoserine(CK2)HMM predict
115O-linkedHMM predict
115Phosphoserine(CK1)HMM predict
115Phosphoserine(PKB)HMM predict
117Phosphoserine(IKK)HMM predict
181Phosphoserine(PKA)HMM predict
181Phosphoserine(PKG)HMM predict
236Phosphothreonine(PKA)HMM predict
410Phosphotyrosine(Syk)HMM predict
593Phosphoserine(CK1)HMM predict
596Phosphoserine(CK1)HMM predict
605Phosphoserine(PKG)HMM predict
605Phosphoserine(IKK)HMM predict
608Phosphoserine(CK1)HMM predict
614Phosphoserine(PKG)HMM predict
614Phosphoserine(PKA)HMM predict
624Phosphoserine(IKK)HMM predict
638Phosphothreonine(PKC)HMM predict
704Phosphotyrosine(SRC)HMM predict
705Phosphoserine(SRC)HMM predict
779N-linkedHMM predict
817N-linkedHMM predict
821N-linkedHMM predict
888N-linkedHMM predict
974SulfotyrosineHMM predict
975Phosphoserine(ATM)HMM predict
978Phosphotyrosine(Syk)HMM predict
996Phosphoserine(IKK)HMM predict
1047Phosphoserine(CDC2)HMM predict
1123Phosphoserine(PKA)HMM predict
1216N-linkedHMM predict
1217N-linkedHMM predict
1232Phosphoserine(CDK)HMM predict
1232Phosphoserine(CDC2)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001115
  • Location:chr8 131861728-132123853
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
NRSF pAbJurkat 132133285 132133910 625 9744
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T30-glioblastomaGSE21026 131843196 131844402 1206 17930
FOXA1 MCF7GSE15244 131847615 131847925 310 13959
P300 T30-glioblastomaGSE21026 131843115 131844261 1146 18041
hScc1 CdLSGSE12603 131846022 131846514 492 15461
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF JurkatGSE12889 131884114 131884317 203 0
FOXA1 DLD1GSE12801 131976356 131977268 912 0
FOXA1 DLD1GSE12801 132071820 132072254 434 0
FOXA1 DLD1GSE12801 132113780 132114127 347 0
FoxA1 MCF7MACSdata 132000733 132000954 221 0
FoxA1 MCF7MACSdata 132001606 132001754 148 0
NRSF JurkatGSE13047 131889949 131890716 767 0
NRSF JurkatGSE13047 131902669 131903005 336 0
NRSF JurkatGSE13047 132118257 132118869 612 0
NRSF JurkatSISSRdata 131902709 131902867 158 0
NRSF JurkatSISSRdata 132118441 132118774 333 0
NRSF mAbJurkat 131889515 131889790 275 0
NRSF mAbJurkat 131890271 131893814 3543 0
NRSF mAbJurkat 132117874 132120742 2868 0
NRSF-mono JurkatQuESTdata 131890020 131890679 659 0
NRSF-mono JurkatQuESTdata 131902720 131903004 284 0
NRSF-mono JurkatQuESTdata 132118256 132118862 606 0
NRSF pAbJurkat 132117976 132118679 703 0
NRSF-poly JurkatQuESTdata 131890080 131890559 479 0
NRSF-poly JurkatQuESTdata 132118299 132118913 614 0
Oct1 H2O2-HelaGSE14283 132044149 132044190 41 0
Oct1 HelaGSE14283 132044149 132044192 43 0
Oct1 HelaGSE14283 132050043 132050078 35 0
Oct4 ESGSE20650 131910461 131910697 236 0
Stat6 IL-4-hr4GSE17850 131929070 131929581 511 0
hScc1 BcellGSE12603 131883858 131884128 270 0
hScc1 BcellGSE12603 132118221 132118785 564 0
hScc1 BcellGSE12603 132120777 132121641 864 0
hScc1 CdLSGSE12603 131883824 131884128 304 0
hScc1 CdLSGSE12603 132118120 132118965 845 0
hScc1 G2GSE9613 132118221 132118708 487 0
p63 keratinocytesGSE17611 131985594 131986582 988 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
25970 EST chr8 132016836 132031093 78 mRNA ADCY8 chr8 131861728 132123854Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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