AutismKB 2.0

Annotation Detail for PGLYRP2


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Basic Information Top
Gene Symbol:PGLYRP2 ( HMFT0141,PGLYRPL,PGRP-L,PGRPL,TAGL-like,tagL,tagL-alpha,tagl-beta )
Gene Full Name: peptidoglycan recognition protein 2
Band: 19p13.12
Quick LinksEntrez ID:114770; OMIM: 608199; Uniprot ID:PGRP2_HUMAN; ENSEMBL ID: ENSG00000161031; HGNC ID: 30013
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
77N-linked (GlcNAc...).
239Phosphoserine.
274Deamidated asparagine.
322Deamidated asparagine.
367N-linked (GlcNAc...).
485N-linked (GlcNAc...).
Location(AA) Modifications Resource
77N-linked (GlcNAc...).Swiss-Prot 53.0
239Phosphoserine.Swiss-Prot 53.0
2663-oxoalanine (Ser).Swiss-Prot 53.0
274Deamidated asparagine.Swiss-Prot 53.0
322Deamidated asparagine.Swiss-Prot 53.0
367N-linked (GlcNAc...).Swiss-Prot 53.0
485N-linked (GlcNAc...).Swiss-Prot 53.0
Location(AA) Modification Resource
77N-linkedHMM predict
87Phosphoserine(MAPK)HMM predict
108Phosphotyrosine(Jak)HMM predict
117O-linkedHMM predict
168O-linkedHMM predict
168O-linkedHMM predict
169PhosphoserineHMM predict
181O-linkedHMM predict
189Phosphothreonine(MAPK)HMM predict
210Phosphoserine(IKK)HMM predict
235Phosphoserine(IKK)HMM predict
237Phosphothreonine(PKC)HMM predict
289Phosphothreonine(CDC2)HMM predict
295Phosphoserine(CK1)HMM predict
327Phosphothreonine(PKC)HMM predict
367N-linkedHMM predict
456Phosphotyrosine(INSR)HMM predict
485N-linkedHMM predict
498Phosphothreonine(PKC)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_052890
  • Location:chr19 15440462-15451311
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER Breast-CancerGSE22609 15451183 15451625 442 93
ER MCF7GSE19013 15450830 15452379 1549 293
ER MCF7GSE19013 15457475 15458086 611 6469
FOXA1 MCF7GSE15244 15460233 15460945 712 9278
RARA MCF7GSE15244 15460233 15460945 712 9278
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER Fulvestrant-MCF7GSE14664 15421786 15421818 32 18661
FOXA1 MCF7GSE15244 15439070 15439309 239 1273
H3K27me3 colorectalcancer 15426630 15427352 722 13472
KLF4 hESGSE17917 15421772 15422049 277 18552
RARA MCF7GSE15244 15439070 15439309 239 1273
TFAP2C MCF7GSE21234 15423613 15424144 531 16584
VDR GM10855-UnstimGSE22484 15421439 15423329 1890 18079
hScc1 BcellGSE12603 15428681 15429608 927 11318
hScc1 BcellGSE12603 15435814 15436149 335 4481
p130 SenescentGSE19898 15420851 15421045 194 19515
p130 SenescentGSE19898 15424405 15424669 264 15926
p130 shRbSenescentGSE19898 15424450 15424990 540 15743
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T0-glioblastomaGSE21026 15445283 15445511 228 0
CTCF G2GSE9613 15441257 15441594 337 0
H3K27me3 colorectalcancer 15440571 15441293 722 0
RARA MCF7GSE15244 15440434 15441414 980 0
hScc1 BcellGSE12603 15443379 15443721 342 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018