AutismKB 2.0

Annotation Detail for SORCS1


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Basic Information Top
Gene Symbol:SORCS1 ( FLJ41758,FLJ43475,FLJ44957 )
Gene Full Name: sortilin-related VPS10 domain containing receptor 1
Band: 10q25.1
Quick LinksEntrez ID:114815; OMIM: 606283; Uniprot ID:SORC1_HUMAN; ENSEMBL ID: ENSG00000108018; HGNC ID: 16697
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
184N-linked (GlcNAc...) (Potential).
352N-linked (GlcNAc...) (Potential).
433N-linked (GlcNAc...) (Potential).
765N-linked (GlcNAc...) (Potential).
776N-linked (GlcNAc...) (Potential).
816N-linked (GlcNAc...) (Potential).
847N-linked (GlcNAc...) (Potential).
908N-linked (GlcNAc...) (Potential).
929N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
184N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
352N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
433N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
765N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
776N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
816N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
847N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
908N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
929N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
37S-palmitoylHMM predict
38S-palmitoylHMM predict
40Phosphoserine(CDC2)HMM predict
44O-linkedHMM predict
49Phosphoserine(IKK)HMM predict
51PhosphoserineHMM predict
51Phosphoserine(PKB)HMM predict
68Phosphothreonine(MAPK)HMM predict
88Phosphoserine(CK1)HMM predict
111Phosphoserine(IKK)HMM predict
111Phosphoserine(PKG)HMM predict
111Phosphoserine(CAMK2)HMM predict
111Phosphoserine(PKB)HMM predict
111Phosphoserine(PKC)HMM predict
129MethylarginineHMM predict
184N-linkedHMM predict
217Phosphotyrosine(INSR)HMM predict
291Phosphoserine(ATM)HMM predict
297Phosphotyrosine(INSR)HMM predict
352N-linkedHMM predict
357N-linkedHMM predict
365Phosphotyrosine(INSR)HMM predict
433N-linkedHMM predict
437N-linkedHMM predict
732SulfotyrosineHMM predict
749N-linkedHMM predict
765N-linkedHMM predict
769Phosphotyrosine(EGFR)HMM predict
776N-linkedHMM predict
816N-linkedHMM predict
847N-linkedHMM predict
908N-linkedHMM predict
916O-linkedHMM predict
929N-linkedHMM predict
930N-linkedHMM predict
982Phosphoserine(PKA)HMM predict
990SulfotyrosineHMM predict
1050Phosphothreonine(CK2)HMM predict
1050Phosphothreonine(PKA)HMM predict
1095Phosphothreonine(MAPK)HMM predict
1097Phosphothreonine(MAPK)HMM predict
1130Phosphoserine(MAPK)HMM predict
1130O-linkedHMM predict
1133Phosphoserine(CDC2)HMM predict
1133Phosphoserine(IKK)HMM predict
1133O-linkedHMM predict
1135O-linkedHMM predict
1152Phosphothreonine(CDK)HMM predict
1152O-linkedHMM predict
1152Phosphothreonine(MAPK)HMM predict
1156Phosphothreonine(CDC2)HMM predict
1156Phosphothreonine(MAPK)HMM predict
1156Phosphothreonine(CDK)HMM predict
1157ProlineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001013031
  • Location:chr10 108323411-108914281
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3K27me3 colorectalcancer 108915007 108915417 410 931
Oct1 HelaGSE14283 108917084 108917114 30 2818
TFAP2C MCF7GSE21234 108930442 108930740 298 16310
hScc1 BcellGSE12603 108914463 108914674 211 287
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FOXA1 MCF7GSE15244 108307883 108308508 625 15216
FoxA1 MCF7MACSdata 108308157 108308424 267 15121
RARG MCF7GSE15244 108307883 108308472 589 15234
TFAP2C MCF7GSE21234 108322768 108323362 594 347
hScc1 BcellGSE12603 108321437 108321684 247 1851
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 108374698 108374873 175 0
CTCF CD4GSE12889 108455417 108455592 175 0
CTCF CD4SISSRdata 108374698 108374873 175 0
CTCF CD4SISSRdata 108455417 108455592 175 0
CTCF HelaGSE12889 108374673 108374890 217 0
ER E2-MCF7GSE14664 108587140 108587178 38 0
FOXA1 MCF7GSE15244 108355610 108356379 769 0
FoxA1 MCF7MACSdata 108844799 108845258 459 0
GABP HelaGSE8489 108817667 108818152 485 0
Gata2 K562GSE18868 108461046 108461534 488 0
H3K27me3 colorectalcancer 108913226 108913761 535 0
KLF4 hESGSE17917 108374714 108375026 312 0
Myc K562GSE19551 108772517 108773122 605 0
Myc K562GSE19551 108806004 108806218 214 0
NFkBII GM12878GSE19485 108680106 108682671 2565 0
NFkBII GM15510GSE19485 108680328 108682008 1680 0
NRSF JurkatGSE13047 108894198 108894708 510 0
NRSF JurkatSISSRdata 108894339 108894602 263 0
NRSF mAbJurkat 108893688 108895076 1388 0
NRSF-mono JurkatQuESTdata 108894197 108894725 528 0
NRSF-poly JurkatQuESTdata 108894232 108894697 465 0
Nanog ESGSE20650 108364842 108365271 429 0
Nanog ESGSE20650 108458183 108458829 646 0
Nanog ESGSE20650 108669761 108670199 438 0
Nanog hESGSE18292 108401572 108401813 241 0
Nanog hESGSE18292 108639023 108639304 281 0
Nanog hESGSE18292 108669840 108670098 258 0
Oct1 H2O2-HelaGSE14283 108343089 108343117 28 0
Oct1 H2O2-HelaGSE14283 108358729 108358757 28 0
Oct1 H2O2-HelaGSE14283 108390959 108390993 34 0
Oct1 H2O2-HelaGSE14283 108662583 108662612 29 0
Oct1 H2O2-HelaGSE14283 108678451 108678486 35 0
Oct1 H2O2-HelaGSE14283 108901183 108901210 27 0
Oct1 H2O2-HelaGSE14283 108912739 108912766 27 0
Oct1 HelaGSE14283 108516528 108516560 32 0
Oct1 HelaGSE14283 108587138 108587172 34 0
Oct1 HelaGSE14283 108662582 108662619 37 0
Oct1 HelaGSE14283 108678450 108678484 34 0
Oct1 HelaGSE14283 108765564 108765611 47 0
Oct1 HelaGSE14283 108768840 108768869 29 0
Oct4 hESGSE21916 108457413 108457976 563 0
Oct4 hESGSE21916 108458239 108458774 535 0
Oct4 hESGSE21916 108661966 108662483 517 0
P300 T30-glioblastomaGSE21026 108355831 108356641 810 0
PAX3-FKHR Rh4GSE19063 108504152 108505542 1390 0
PAX3-FKHR Rh4GSE19063 108731142 108732795 1653 0
PAX3-FKHR Rh4GSE19063 108847773 108848845 1072 0
RARA MCF7GSE15244 108355723 108356379 656 0
RARG MCF7GSE15244 108355763 108356379 616 0
RNAII Tamoxifen-MCF7GSE14664 108661284 108661373 89 0
RNAII Tamoxifen-MCF7GSE14664 108666854 108666941 87 0
Rb GrowingGSE19898 108487460 108487596 136 0
Rb GrowingGSE19898 108761115 108761336 221 0
STAT1 HeLaGSE12783 108753981 108754988 1007 0
Stat6 IL-4-hr1GSE17850 108455072 108455444 372 0
TAF k562GSE8489 108692563 108692937 374 0
TFAP2C MCF7GSE21234 108402088 108402396 308 0
TFAP2C MCF7GSE21234 108737180 108737487 307 0
hScc1 BcellGSE12603 108374542 108375009 467 0
hScc1 BcellGSE12603 108455230 108455697 467 0
hScc1 BcellGSE12603 108461066 108461482 416 0
hScc1 BcellGSE12603 108545260 108545813 553 0
hScc1 BcellGSE12603 108613303 108613721 418 0
hScc1 BcellGSE12603 108730864 108731286 422 0
hScc1 CdLSGSE12603 108374542 108375327 785 0
hScc1 CdLSGSE12603 108455159 108455846 687 0
hScc1 CdLSGSE12603 108460994 108461677 683 0
hScc1 CdLSGSE12603 108545155 108545849 694 0
hScc1 CdLSGSE12603 108613303 108613685 382 0
hScc1 CdLSGSE12603 108685816 108686074 258 0
hScc1 CdLSGSE12603 108730715 108731355 640 0
hScc1 CdLSGSE12603 108867056 108867297 241 0
hScc1 G2GSE9613 108374542 108375118 576 0
hScc1 G2GSE9613 108545399 108545777 378 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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