AutismKB 2.0

Annotation Detail for OSBPL6


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Basic Information Top
Gene Symbol:OSBPL6 ( FLJ36583,MGC59642,ORP6 )
Gene Full Name: oxysterol binding protein-like 6
Band: 2q31.2
Quick LinksEntrez ID:114880; OMIM: 606734; Uniprot ID:OSBL6_HUMAN; ENSEMBL ID: ENSG00000079156; HGNC ID: 16388
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
2Phosphoserine.
44Phosphoserine.
229Phosphoserine.
343Phosphoserine.
428Phosphoserine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
15O-linkedHMM predict
16Phosphothreonine(CDK)HMM predict
16Phosphothreonine(MAPK)HMM predict
23Phosphoserine(CK1)HMM predict
23Phosphoserine(CK2)HMM predict
23O-linkedHMM predict
27Phosphoserine(CK1)HMM predict
28Phosphoserine(ATM)HMM predict
44Phosphoserine(CK2)HMM predict
44Phosphoserine(PKG)HMM predict
45Phosphoserine(CDC2)HMM predict
46O-linkedHMM predict
50Phosphoserine(CK1)HMM predict
159Phosphotyrosine(SRC)HMM predict
190Phosphoserine(CDC2)HMM predict
202O-linkedHMM predict
203O-linkedHMM predict
240O-linkedHMM predict
293N-linkedHMM predict
312Phosphothreonine(PKA)HMM predict
312Phosphothreonine(PKC)HMM predict
317Phosphothreonine(PKA)HMM predict
356Phosphothreonine(CDC2)HMM predict
371SulfotyrosineHMM predict
371Phosphotyrosine(Jak)HMM predict
371Phosphotyrosine(INSR)HMM predict
413Phosphoserine(CK1)HMM predict
426Phosphoserine(PKG)HMM predict
428Phosphoserine(IKK)HMM predict
428Phosphoserine(ATM)HMM predict
462Phosphoserine(CDC2)HMM predict
477Phosphoserine(ATM)HMM predict
487Phosphoserine(CK1)HMM predict
487Phosphoserine(IKK)HMM predict
491Phosphoserine(ATM)HMM predict
491Phosphoserine(PKG)HMM predict
507Phosphoserine(CK1)HMM predict
508Phosphoserine(CK2)HMM predict
513Phosphoserine(CK1)HMM predict
513Phosphoserine(CK2)HMM predict
518SulfotyrosineHMM predict
520Phosphoserine(ATM)HMM predict
525N-linkedHMM predict
527Phosphoserine(CK2)HMM predict
530N-linkedHMM predict
532Phosphoserine(CK2)HMM predict
536N-linkedHMM predict
598Phosphothreonine(PKC)HMM predict
608Phosphotyrosine(SRC)HMM predict
616Phosphoserine(CK2)HMM predict
826SulfotyrosineHMM predict
885Phosphotyrosine(INSR)HMM predict
913N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_032523
  • Location:chr2 178767619-178969118
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 178766744 178768110 1366 193
FOXA1 MCF7GSE15244 178766144 178767002 858 1047
FoxA1 MCF7MACSdata 178766438 178766744 306 1029
H3K27me3 colorectalcancer 178761392 178761920 528 5964
Oct1 HelaGSE14283 178755536 178755566 30 12069
Rb SenescentGSE19898 178767325 178767721 396 97
hScc1 BcellGSE12603 178767301 178767714 413 112
hScc1 G2GSE9613 178766859 178768110 1251 135
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 178853222 178853507 285 0
CTCF CD4GSE12889 178879453 178879631 178 0
CTCF CD4SISSRdata 178853222 178853507 285 0
CTCF CD4SISSRdata 178879453 178879631 178 0
Fos K562GSE19551 178815170 178815611 441 0
Gata2 K562GSE18868 178842573 178843321 748 0
Gata2 K562GSE18868 178846543 178847320 777 0
Jun K562GSE19551 178815157 178815722 565 0
Nanog ESGSE20650 178784602 178785521 919 0
Nanog hESGSE18292 178792266 178792628 362 0
Oct1 H2O2-HelaGSE14283 178825072 178825110 38 0
Oct1 H2O2-HelaGSE14283 178870384 178870436 52 0
Oct1 HelaGSE14283 178842649 178842689 40 0
Oct1 HelaGSE14283 178870379 178870440 61 0
Oct4 ESGSE20650 178785002 178785373 371 0
Oct4 ESGSE20650 178792259 178792733 474 0
Oct4 hESGSE17917 178785016 178785368 352 0
Oct4 hESGSE21916 178784714 178785501 787 0
PHF8 293TGSE20725 178766769 178768515 1746 0
PHF8 HeLaGSE20725 178766838 178768540 1702 0
STAT1 HeLaGSE12782 178794544 178795762 1218 0
STAT1 HeLaGSE12783 178794578 178795652 1074 0
Sox2 hESGSE18292 178792162 178792730 568 0
USF1 HepG2E 178850402 178851719 1317 0
USF2 HepG2E 178850611 178851137 526 0
hScc1 BcellGSE12603 178853242 178853451 209 0
p63 keratinocytesGSE17611 178844747 178845684 937 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018