Annotation Detail for DHRS1

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Basic Information Top

Gene Symbol:	DHRS1 ( DKFZp586I0523,FLJ14250,FLJ25430,MGC20204,SDR19C1 )
Gene Full Name:	dehydrogenase/reductase (SDR family) member 1
Band:	14q12
Quick Links	Entrez ID:115817; OMIM: 610410; Uniprot ID:DHRS1_HUMAN; ENSEMBL ID: ENSG00000157379; HGNC ID: 16445
Relate to Another Database:	SFARIGene; denovo-db

Pathways, Diseases and Drugs

TF binding site

Post Translation Modification

PTM Sites from Uniprot:0 results
Experimental PTM Sites from dbPTM:0 results
Predicted PTM Sites by profile HMM from dbPTM:4 results

No data

Location(AA)	Modification	Resource
53	Phosphoserine(CK1)	HMM predict
151	Phosphoserine(CDC2)	HMM predict
275	Phosphotyrosine(Jak)	HMM predict
277	Phosphoserine(CK1)	HMM predict

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

RefSeq ID: NM_138452
Location:chr14 23829645-23838505
strand:-

Upstream the gene:0 results
Downstream the gene:3 results
Inside the gene:14 results

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	G2	GSE9613	23819983	23820325	342	9492
CTCF	G2	GSE9613	23822897	23823506	609	6444
TFAP2C	MCF7	GSE21234	23828871	23829394	523	513

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	CD4	GSE12889	23835966	23836303	337	0
CTCF	CD4	SISSRdata	23835966	23836303	337	0
CTCF	G2	GSE9613	23830011	23830306	295	0
CTCF	G2	GSE9613	23835623	23837056	1433	0
CTCF	G2	GSE9613	23837920	23838546	626	0
H3K4me3	colorectal	cancer	23837920	23838479	559	0
H3ac	HepG2	E	23835253	23837056	1803	0
H3ac	HepG2	E	23837394	23837597	203	0
H3ac	HepG2	E	23837920	23838618	698	0
TFAP2C	MCF7	GSE21234	23837792	23838348	556	0
hScc1	Bcell	GSE12603	23835560	23836813	1253	0
hScc1	CdLS	GSE12603	23835595	23837056	1461	0
p130	Senescent	GSE19898	23835786	23836304	518	0
p130	shRbQuiescent	GSE19898	23838028	23838946	918	0

Validated miRNA targets

Cis-Nats regulation

Cluster ID	Plue Type	Plus Gene Name	Plus Chromosome	Plus Start	Plus End	Overlap Length	Minus Type	Minus Gene Name	Minus Chromosome	Minus Star	Minus End	Type
7717	EST		chr14	23831226	23837830	147	mRNA	DHRS1	chr14	23829645	23838506	Sense/Antisense (SA) pairs

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

Studies: 1,036
Genes: 1,379
CNVs/SVs: 5,420
SNVs/Indels: 11,669
de novo Mutations: 5,669
Mosaics: 789
Linkage Regions: 172

Paper Collected: 6/30/2018

Last Update: 8/26/2018

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