Annotation Detail for CLCN3
Basic Information Top
| Gene Symbol: | CLCN3 ( CLC3,ClC-3 ) |
|---|---|
| Gene Full Name: | chloride channel 3 |
| Band: | 4q33 |
| Quick Links | Entrez ID:1182; OMIM: 600580; Uniprot ID:CLCN3_HUMAN; ENSEMBL ID: ENSG00000109572; HGNC ID: 2021 |
| Relate to Another Database: | SFARIGene; denovo-db |
| Location(AA) | Modification | |
|---|---|---|
| 177 | N-linked (GlcNAc...) (Potential). | |
| 242 | Selectivity filter part_1 (By | |
| 284 | Selectivity filter part_2 (By | |
| 451 | N-linked (GlcNAc...) (Potential). | |
| 479 | N-linked (GlcNAc...) (Potential). | |
| 529 | Selectivity filter part_3 (By | |
| Location(AA) | Modifications | Resource |
|---|---|---|
| 8 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 |
| 51 | Phosphoserine (CaM-KIIalpha) | Phospho.ELM 6.0 |
| 119 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 |
| 393 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 |
| 421 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 |
| 618 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 |
| 629 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 |
| Location(AA) | Modification | Resource |
|---|---|---|
| 8 | N-linked | HMM predict |
| 51 | Phosphoserine(PKG) | HMM predict |
| 119 | N-linked | HMM predict |
| 232 | S-palmitoyl | HMM predict |
| 233 | S-palmitoyl | HMM predict |
| 362 | Phosphoserine(PKG) | HMM predict |
| 362 | Phosphoserine(PKB) | HMM predict |
| 363 | Phosphothreonine(PKA) | HMM predict |
| 421 | N-linked | HMM predict |
| 492 | Sulfotyrosine | HMM predict |
| 516 | Phosphotyrosine(Abl) | HMM predict |
| 532 | Phosphothreonine(PKA) | HMM predict |
| 548 | Phosphotyrosine(INSR) | HMM predict |
| 558 | Phosphothreonine(PKC) | HMM predict |
| 572 | Phosphotyrosine(EGFR) | HMM predict |
| 618 | N-linked | HMM predict |
| 629 | N-linked | HMM predict |
| 633 | Phosphotyrosine(EGFR) | HMM predict |
| 634 | N-linked | HMM predict |
| 641 | Phosphoserine(CK1) | HMM predict |
| 684 | Phosphoserine(MAPK) | HMM predict |
| 689 | Phosphoserine | HMM predict |
| 710 | Phosphothreonine(MAPK) | HMM predict |
- RefSeq ID: NM_001829
- Location:chr4 170778296-170878730
- strand:+
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| CTCF | G2 | GSE9613 | 170776854 | 170778299 | 1445 | 720 |
| H3ac | HepG2 | E | 170777115 | 170777767 | 652 | 856 |
| Myc | hES | GSE17917 | 170777319 | 170777527 | 208 | 874 |
| PHF8 | 293T | GSE20725 | 170777708 | 170778670 | 962 | 108 |
| hScc1 | Bcell | GSE12603 | 170777876 | 170778241 | 365 | 238 |
| No data |
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| FoxA1 | MCF7 | MACSdata | 170792631 | 170792921 | 290 | 0 |
| Gata1 | K562 | GSE18868 | 170817550 | 170818221 | 671 | 0 |
| Gata2 | K562 | GSE18868 | 170817651 | 170818094 | 443 | 0 |
| H3K4me3 | colorectal | cancer | 170778345 | 170778981 | 636 | 0 |
| H3ac | HepG2 | E | 170778205 | 170779101 | 896 | 0 |
| H3ac | HepG2 | E | 170779428 | 170780074 | 646 | 0 |
| Myc | K562 | GSE19551 | 170836322 | 170836495 | 173 | 0 |
| Nanog | hES | GSE18292 | 170836319 | 170836514 | 195 | 0 |
| P300 | T30-glioblastoma | GSE21026 | 170817424 | 170818494 | 1070 | 0 |
| PolII | HeLa | GSE12783 | 170777008 | 170780680 | 3672 | 0 |
| PolII | HeLa | GSE12783 | 170816989 | 170818740 | 1751 | 0 |
| Rb | Growing | GSE19898 | 170817735 | 170817848 | 113 | 0 |
| TAF | Hela | GSE8489 | 170778414 | 170780038 | 1624 | 0 |
| TAF | Hela | GSE8489 | 170817022 | 170818107 | 1085 | 0 |
| p130 | Quiescent | GSE19898 | 170817688 | 170817973 | 285 | 0 |
| p130 | Senescent | GSE19898 | 170778201 | 170778482 | 281 | 0 |
| Micro RNA Name | Stem Loop Name | The chromosome that miRNA located | Publication |
|---|---|---|---|
| hsa-let-7c | hsa-let-7c | 21 | 18006822 |
| hsa-let-7c* | hsa-let-7c | 21 | 18006822 |
| hsa-miR-1 | hsa-mir-1-2 | 18 | 15685193 |
| hsa-miR-1 | hsa-mir-1-1 | 20 | 15685193 |
| hsa-miR-10a | hsa-mir-10a | 17 | 18006822 |
| hsa-miR-10a* | hsa-mir-10a | 17 | 18006822 |
| hsa-miR-124 | hsa-mir-124-1 | 8 | 15685193 |
| hsa-miR-124 | hsa-mir-124-2 | 8 | 15685193 |
| hsa-miR-124 | hsa-mir-124-3 | 20 | 15685193 |
| hsa-miR-144 | hsa-mir-144 | 17 | 18006822 |
| hsa-miR-144* | hsa-mir-144 | 17 | 18006822 |
| hsa-miR-150 | hsa-mir-150 | 19 | 18006822 |
| hsa-miR-150* | hsa-mir-150 | 19 | 18006822 |
| hsa-miR-155 | hsa-mir-155 | 21 | 18006822 |
| hsa-miR-155* | hsa-mir-155 | 21 | 18006822 |
| hsa-miR-373 | hsa-mir-373 | 19 | 15685193 |
| hsa-miR-373* | hsa-mir-373 | 19 | 15685193 |
| ID in Tarbase | Data Type | Support Type | miRNA | Gene | Direct Support | Publication |
|---|---|---|---|---|---|---|
| 129 | Unknown | MicroArray | miR-1 | CLCN3 | n_a | 15685193 |
| Ensembl | Protein Type | Differentially expressed in | Pathology or Event | Mis Regulation | Gene Expression | Tumour Involvement |
| ENSG00000109572 | "cardiac and skeletal muscles, cardiogenesis" | n_a | n_a | "epithelium, lymphocyte, muscle cell" | "benign tumour, malignant tumour, carcinoma, leukaemia, sarcoma" |
Cis-Nats regulation