AutismKB 2.0

Annotation Detail for CLCN4


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Basic Information Top
Gene Symbol:CLCN4 ( CLC4,ClC-4,ClC-4A,MGC163150 )
Gene Full Name: chloride channel 4
Band: Xp22.2
Quick LinksEntrez ID:1183; OMIM: 302910; Uniprot ID:CLCN4_HUMAN; ENSEMBL ID: ENSG00000073464; HGNC ID: 2022
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
184Selectivity filter part_1 (By
226Selectivity filter part_2 (By
471Selectivity filter part_3 (By
Location(AA) Modifications Resource
Location(AA) Modification Resource
43Phosphothreonine(PKA)HMM predict
50Phosphothreonine(PKC)HMM predict
119N-linkedHMM predict
149Phosphotyrosine(INSR)HMM predict
304Phosphothreonine(PKC)HMM predict
362Phosphothreonine(PKA)HMM predict
363Phosphothreonine(PKA)HMM predict
395Phosphoserine(IKK)HMM predict
416SulfotyrosineHMM predict
421N-linkedHMM predict
516Phosphotyrosine(Abl)HMM predict
532Phosphothreonine(PKA)HMM predict
548Phosphotyrosine(INSR)HMM predict
558Phosphothreonine(PKC)HMM predict
572Phosphotyrosine(EGFR)HMM predict
594Phosphothreonine(PKA)HMM predict
597Phosphothreonine(PKA)HMM predict
631Phosphotyrosine(Syk)HMM predict
631Phosphotyrosine(EGFR)HMM predict
698N-linkedHMM predict
708Phosphothreonine(MAPK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001830
  • Location:chrX 10085036-10163519
  • strand:+
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T0-glioblastomaGSE21026 10167356 10167931 575 4124
ER Fulvestrant-MCF7GSE14664 10171697 10171748 51 8203
Oct1 HelaGSE14283 10171105 10171147 42 7607
Oct1 HelaGSE14283 10171706 10171747 41 8207
Oct1 HelaGSE14283 10177846 10177897 51 14352
hScc1 BcellGSE12603 10183169 10183619 450 19875
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T30-glioblastomaGSE21026 10118189 10119034 845 0
CTCF CD4GSE12889 10117729 10117921 192 0
CTCF CD4SISSRdata 10117729 10117921 192 0
ER Breast-CancerGSE22609 10087705 10088483 778 0
ER MCF7GSE19013 10087521 10088327 806 0
Nanog hESGSE18292 10118518 10118727 209 0
Oct1 H2O2-HelaGSE14283 10087919 10087961 42 0
Oct1 HelaGSE14283 10087921 10087961 40 0
Oct1 HelaGSE14283 10121499 10121532 33 0
P300 T30-glioblastomaGSE21026 10118463 10118863 400 0
USF1 HepG2E 10084225 10086164 1939 0
hScc1 BcellGSE12603 10117666 10117981 315 0
hScc1 BcellGSE12603 10118470 10118847 377 0
hScc1 BcellGSE12603 10151320 10151759 439 0
hScc1 CdLSGSE12603 10117666 10117981 315 0
hScc1 CdLSGSE12603 10118470 10118932 462 0
hScc1 G2GSE9613 10118470 10118847 377 0
p130 shRbSenescentGSE19898 10161195 10161490 295 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018