AutismKB 2.0

Annotation Detail for CLIC1


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Basic Information Top
Gene Symbol:CLIC1 ( G6,NCC27 )
Gene Full Name: chloride intracellular channel 1
Band: 6p21.33
Quick LinksEntrez ID:1192; OMIM: 602872; Uniprot ID:CLIC1_HUMAN; ENSEMBL ID: ENSG00000213719; HGNC ID: 2062
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
2N-acetylalanine.
13N6-acetyllysine.
24S-glutathionyl cysteine.
119N6-acetyllysine.
131N6-acetyllysine.
135N6-acetyllysine.
233Phosphotyrosine (By similarity).
Location(AA) Modifications Resource
2N-acetylalanine.Swiss-Prot 53.0
Location(AA) Modification Resource
42N-linkedHMM predict
52Phosphothreonine(PKA)HMM predict
117Phosphotyrosine(INSR)HMM predict
146Phosphoserine(CDC2)HMM predict
146Phosphoserine(MAPK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001288
  • Location:chr6 31806338-31812319
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3ac HepG2E 31813224 31813967 743 1276
hScc1 BcellGSE12603 31812238 31812678 440 139
p130 QuiescentGSE19898 31813645 31814050 405 1528
p130 SenescentGSE19898 31812495 31812787 292 322
p130 SenescentGSE19898 31813629 31813978 349 1484
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
hScc1 BcellGSE12603 31806172 31806486 314 10
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 31810578 31811199 621 0
CTCF G2GSE9613 31812112 31812408 296 0
H3K4me3 colorectalcancer 31811043 31812151 1108 0
H3ac HepG2E 31809075 31812678 3603 0
PHF8 293TGSE20725 31811784 31812731 947 0
PolII HeLaGSE12783 31809529 31813003 3474 0
Rb GrowingGSE19898 31812120 31812380 260 0
Rb SenescentGSE19898 31812104 31812512 408 0
TAF HelaGSE8489 31811199 31811842 643 0
TAF k562GSE8489 31810877 31812032 1155 0
TFAP2C MCF7GSE21234 31810482 31811796 1314 0
USF2 HepG2E 31811333 31811961 628 0
p130 QuiescentGSE19898 31812017 31812436 419 0
p130 SenescentGSE19898 31811765 31812347 582 0
p130 shRbQuiescentGSE19898 31811936 31812390 454 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018