AutismKB 2.0

Annotation Detail for ADD3


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Basic Information Top
Gene Symbol:ADD3 ( ADDL )
Gene Full Name: adducin 3 (gamma)
Band: 10q25.1-q25.2
Quick LinksEntrez ID:120; OMIM: 601568; Uniprot ID:ADDG_HUMAN; ENSEMBL ID: ENSG00000148700; HGNC ID: 245
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
12Phosphothreonine.
42Phosphoserine.
402Phosphoserine.
423Phosphoserine.
442Phosphoserine.
673Phosphoserine.
677Phosphoserine.
681Phosphoserine.
683Phosphoserine; by PKC (By similarity).
693Phosphoserine.
Location(AA) Modifications Resource
402Phosphoserine (By similarity).Swiss-Prot 53.0
673Phosphoserine.Swiss-Prot 53.0
673PhosphoserinePhospho.ELM 6.0
677Phosphoserine.Swiss-Prot 53.0
677PhosphoserinePhospho.ELM 6.0
679PhosphoserinePhospho.ELM 6.0
681Phosphoserine (By similarity).Swiss-Prot 53.0
681PhosphoserinePhospho.ELM 6.0
683PhosphoserinePhospho.ELM 6.0
683Phosphoserine (by PKC) (By similarity).Swiss-Prot 53.0
693Phosphoserine.Swiss-Prot 53.0
693Phosphoserine (PKC
Location(AA) Modification Resource
6Phosphoserine(ATM)HMM predict
11O-linkedHMM predict
12Phosphothreonine(CDK)HMM predict
35SulfotyrosineHMM predict
35Phosphotyrosine(EGFR)HMM predict
35Phosphotyrosine(INSR)HMM predict
59Phosphothreonine(PKA)HMM predict
64Phosphoserine(CDC2)HMM predict
84N-linkedHMM predict
108Phosphoserine(IKK)HMM predict
112O-linkedHMM predict
166Phosphoserine(PKG)HMM predict
166Phosphoserine(CK1)HMM predict
251Phosphoserine(ATM)HMM predict
262Phosphotyrosine(Syk)HMM predict
265SulfotyrosineHMM predict
268Phosphoserine(CK2)HMM predict
341Phosphotyrosine(Syk)HMM predict
347O-linkedHMM predict
402Phosphoserine(PKB)HMM predict
423Phosphoserine(CDC2)HMM predict
446Phosphotyrosine(INSR)HMM predict
446Phosphotyrosine(SRC)HMM predict
446Phosphotyrosine(Syk)HMM predict
461Phosphoserine(CDK)HMM predict
475Phosphoserine(CK1)HMM predict
568Phosphothreonine(PKC)HMM predict
585Phosphoserine(CK1)HMM predict
585Phosphoserine(ATM)HMM predict
589Phosphoserine(CK1)HMM predict
589Phosphoserine(IKK)HMM predict
590Phosphoserine(CK1)HMM predict
596Phosphoserine(IKK)HMM predict
596Phosphoserine(ATM)HMM predict
600Phosphoserine(CDC2)HMM predict
600Phosphoserine(IKK)HMM predict
650Phosphoserine(CK1)HMM predict
664Phosphoserine(CDC2)HMM predict
664Phosphoserine(CDK)HMM predict
673Phosphoserine(MAPK)HMM predict
673Phosphoserine(CDC2)HMM predict
673Phosphoserine(CK1)HMM predict
673Phosphoserine(CDK)HMM predict
677Phosphoserine(CDC2)HMM predict
677PhosphoserineHMM predict
679O-linkedHMM predict
681Phosphoserine(CDC2)HMM predict
681Phosphoserine(CDK)HMM predict
683Phosphoserine(PKC)HMM predict
693Phosphoserine(PKA)HMM predict
693Phosphoserine(PKC)HMM predict
706AlanineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001121
  • Location:chr10 111757700-111885309
  • strand:+
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER E2-MCF7GSE14664 111887685 111887730 45 2398
Fos K562GSE19551 111892734 111893116 382 7616
Fos K562GSE19551 111903162 111903476 314 18010
P300 T0-glioblastomaGSE21026 111886726 111887435 709 1771
Rb QuiescentGSE19898 111887280 111887487 207 2074
TFAP2C MCF7GSE21234 111891922 111892377 455 6840
hScc1 BcellGSE12603 111886778 111887245 467 1702
hScc1 BcellGSE12603 111901355 111901601 246 16169
hScc1 CdLSGSE12603 111886643 111887302 659 1663
hScc1 CdLSGSE12603 111888041 111888536 495 2979
hScc1 G2GSE9613 111886606 111887302 696 1645
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER Fulvestrant-MCF7GSE14664 111859925 111859964 39 0
H3K4me3 colorectalcancer 111757570 111757986 416 0
H3K4me3 colorectalcancer 111758560 111759012 452 0
H3ac HepG2E 111758370 111759440 1070 0
KLF4 hESGSE17917 111758000 111758229 229 0
NFkBII GM12878GSE19485 111851156 111853202 2046 0
Oct1 HelaGSE14283 111855360 111855396 36 0
Oct1 HelaGSE14283 111873263 111873344 81 0
P300 T30-glioblastomaGSE21026 111806288 111807244 956 0
Stat6 IL-4-hr1GSE17850 111873516 111874105 589 0
hScc1 CdLSGSE12603 111757242 111758291 1049 0
hScc1 CdLSGSE12603 111822164 111822381 217 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-143 hsa-mir-143 5 20460367
hsa-miR-143* hsa-mir-143 5 20460367
No data
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
3661 mRNA ADD3 chr10 111755793 111885313 38 EST chr10 111695971 111755831Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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