AutismKB 2.0

Annotation Detail for CLTB


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Basic Information Top
Gene Symbol:CLTB ( LCB )
Gene Full Name: clathrin, light chain B
Band: 5q35.2
Quick LinksEntrez ID:1212; OMIM: 118970; Uniprot ID:CLCB_HUMAN; ENSEMBL ID: ENSG00000175416; HGNC ID: 2091
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
11Phosphoserine (By similarity).
13Phosphoserine (By similarity).
Location(AA) Modifications Resource
11Phosphoserine (By similarity).Swiss-Prot 53.0
13Phosphoserine (By similarity).Swiss-Prot 53.0
Location(AA) Modification Resource
11Phosphoserine(CK2)HMM predict
13Phosphoserine(CK2)HMM predict
50O-linkedHMM predict
60O-linkedHMM predict
61Phosphoserine(IKK)HMM predict
61O-linkedHMM predict
65O-linkedHMM predict
87Phosphotyrosine(Syk)HMM predict
162Phosphotyrosine(Syk)HMM predict
183Phosphoserine(PKG)HMM predict
187Phosphothreonine(MAPK)HMM predict
217Phosphoserine(CAMK2)HMM predict
225Phosphothreonine(MAPK)HMM predict
225Phosphothreonine(CDK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001834
  • Location:chr5 175752062-175776145
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 175776102 175776513 411 162
CTCF CD4SISSRdata 175776102 175776513 411 162
CTCF HelaGSE12889 175776148 175776479 331 168
CTCF JurkatGSE12889 175776169 175776410 241 144
CTCF G2GSE9613 175775810 175777092 1282 306
hScc1 BcellGSE12603 175775731 175776965 1234 203
hScc1 CdLSGSE12603 175775731 175776584 853 12
p130 SenescentGSE19898 175776278 175776640 362 314
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 175751935 175752570 635 0
CTCF G2GSE9613 175756778 175757797 1019 0
CTCF G2GSE9613 175764152 175764498 346 0
CTCF G2GSE9613 175765496 175765844 348 0
CTCF G2GSE9613 175772616 175772908 292 0
CTCF G2GSE9613 175775333 175775470 137 0
Nanog hESGSE18292 175765381 175765590 209 0
PHF8 293TGSE20725 175775261 175776636 1375 0
TFAP2C MCF7GSE21234 175775213 175775755 542 0
hScc1 BcellGSE12603 175763935 175764498 563 0
p63 keratinocytesGSE17611 175759944 175761065 1121 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018