AutismKB 2.0

Annotation Detail for SPIC


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Basic Information Top
Gene Symbol:SPIC ( MGC40611,SPI-C )
Gene Full Name: Spi-C transcription factor (Spi-1/PU.1 related)
Band: 12q23.2
Quick LinksEntrez ID:121599; OMIM: 612568; Uniprot ID:SPIC_HUMAN; ENSEMBL ID: ENSG00000166211; HGNC ID: 29549
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
50N-linkedHMM predict
64Phosphotyrosine(SRC)HMM predict
88N-linkedHMM predict
92N-linkedHMM predict
190Phosphothreonine(PKA)HMM predict
190Phosphothreonine(PKC)HMM predict
223Phosphotyrosine(Syk)HMM predict
234N-linkedHMM predict
239N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_152323
  • Location:chr12 100394787-100404904
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T30-glioblastomaGSE21026 100377606 100378204 598 16883
CTCF G2GSE9613 100392366 100392801 435 2204
FOXA1 DLD1GSE12801 100393799 100394475 676 651
Nanog ESGSE20650 100391946 100392415 469 2607
Nanog hESGSE18292 100391947 100392341 394 2644
Oct1 HelaGSE14283 100387380 100387413 33 7391
P300 T30-glioblastomaGSE21026 100377574 100378421 847 16790
Sox2 hESGSE18292 100392033 100392339 306 2602
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 100408158 100408424 266 3387
FOXA1 DLD1GSE12801 100419671 100420047 376 14955
Myc K562GSE19551 100408272 100408469 197 3466
Oct1 H2O2-HelaGSE14283 100416195 100416222 27 11304
Oct1 HelaGSE14283 100410393 100410459 66 5522
Oct1 HelaGSE14283 100414121 100414148 27 9230
RARA MCF7GSE15244 100419671 100420047 376 14955
RARG MCF7GSE15244 100419671 100419951 280 14907
Sox2 hESGSE18292 100408152 100408633 481 3488
hScc1 BcellGSE12603 100408088 100408737 649 3508
hScc1 CdLSGSE12603 100408088 100408594 506 3437
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 100398853 100399075 222 0
RARG MCF7GSE15244 100404010 100404233 223 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018