AutismKB 2.0

Annotation Detail for SPPL3


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:SPPL3 ( DKFZp586C1324,IMP2,MDHV1887,MGC126674,MGC126676,MGC90402,PRO4332,PSL4 )
Gene Full Name: -
Band: 12q24.31
Quick LinksEntrez ID:121665; OMIM: 608240; Uniprot ID:PSL4_HUMAN; ENSEMBL ID: ENSG00000157837; HGNC ID: 30424
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
6Phosphotyrosine(SRC)HMM predict
7Phosphoserine(SRC)HMM predict
7Phosphoserine(IKK)HMM predict
11O-linkedHMM predict
16Phosphoserine(IKK)HMM predict
16Phosphoserine(ATM)HMM predict
49Phosphoserine(IKK)HMM predict
50N-linkedHMM predict
51Phosphoserine(CK1)HMM predict
51Phosphoserine(IKK)HMM predict
55Phosphoserine(IKK)HMM predict
136S-palmitoylHMM predict
137S-palmitoylHMM predict
186Phosphoserine(PKA)HMM predict
289Phosphotyrosine(Syk)HMM predict
375O-linkedHMM predict
382PhenylalanineHMM predict
383PhenylalanineHMM predict
385PhenylalanineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_139015
  • Location:chr12 119685418-119826533
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 119829745 119830071 326 3375
ER E2-MCF7GSE14664 119835467 119835500 33 8950
Fos K562GSE19551 119826269 119827051 782 127
H3ac HepG2E 119827175 119827542 367 825
H3ac HepG2E 119827897 119828465 568 1648
HIF1 NormHepG2 119826270 119827027 757 115
Myc hESGSE17917 119826440 119826692 252 33
NFkBII GM12892GSE19485 119831530 119832728 1198 5596
Oct1 HelaGSE14283 119835460 119835499 39 8946
PHF8 Hs68plusFBSGSE20725 119826018 119827146 1128 49
RARG MCF7GSE15244 119838832 119839245 413 12505
USF1 HepG2E 119826733 119827542 809 604
USF1 HepG2E 119827897 119828528 631 1679
USF1 HepG2E 119831089 119831335 246 4679
USF2 HepG2E 119826884 119827542 658 680
USF2 HepG2E 119827897 119828465 568 1648
p63 keratinocytesGSE17611 119836841 119837559 718 10667
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 119673693 119674017 324 11564
CTCF G2GSE9613 119683240 119683369 129 2114
ER E2-MCF7GSE14664 119682952 119683032 80 2427
FOXA1 MCF7GSE15244 119682093 119682555 462 3095
FOXA1 MCF7GSE15244 119683650 119684464 814 1362
Oct4 hESGSE17917 119681484 119681913 429 3720
Oct4 hESGSE21916 119681403 119681710 307 3862
RARG MCF7GSE15244 119682170 119683198 1028 2735
TFAP2C MCF7GSE21234 119681555 119682215 660 3534
p63 keratinocytesGSE17611 119683433 119684286 853 1559
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 119779271 119779426 155 0
CTCF CD4SISSRdata 119779271 119779426 155 0
CTCF G2GSE9613 119685514 119685807 293 0
CTCF G2GSE9613 119688520 119689024 504 0
CTCF G2GSE9613 119691005 119691148 143 0
CTCF G2GSE9613 119693326 119693472 146 0
CTCF G2GSE9613 119695421 119695791 370 0
CTCF G2GSE9613 119766759 119767061 302 0
CTCF G2GSE9613 119778766 119779411 645 0
CTCF G2GSE9613 119825741 119827027 1286 0
FOXA1 MCF7GSE15244 119767280 119767617 337 0
FOXA1 MCF7GSE15244 119775397 119775675 278 0
FOXA1 MCF7GSE15244 119807591 119807862 271 0
FoxA1 MCF7MACSdata 119745052 119745275 223 0
H3K4me2 HCT116GSE10453 119824597 119825584 987 0
H3K4me3 colorectalcancer 119824085 119825471 1386 0
H3ac HepG2E 119823818 119825851 2033 0
NRSF pAbJurkat 119825508 119826574 1066 0
Nanog hESGSE18292 119744885 119745303 418 0
Oct1 H2O2-HelaGSE14283 119708378 119708424 46 0
Oct1 HelaGSE14283 119689935 119689967 32 0
Oct1 HelaGSE14283 119708378 119708454 76 0
Oct1 HelaGSE14283 119745822 119745889 67 0
Oct1 HelaGSE14283 119746575 119746606 31 0
Oct1 HelaGSE14283 119767369 119767427 58 0
Oct1 HelaGSE14283 119814554 119814584 30 0
PHF8 HeLaGSE20725 119825303 119827135 1832 0
RARA MCF7GSE15244 119778766 119779233 467 0
RARG MCF7GSE15244 119767280 119767617 337 0
RARG MCF7GSE15244 119824925 119825288 363 0
RUNX JurkatGSE17954 119793724 119793769 45 0
TAF HelaGSE8489 119766677 119767167 490 0
USF1 HepG2E 119823818 119825851 2033 0
hScc1 BcellGSE12603 119778766 119779411 645 0
hScc1 BcellGSE12603 119825182 119826919 1737 0
hScc1 CdLSGSE12603 119779085 119779411 326 0
hScc1 CdLSGSE12603 119825045 119826812 1767 0
hScc1 G2GSE9613 119825923 119826884 961 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved