AutismKB 2.0

Annotation Detail for CCR5


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Basic Information Top
Gene Symbol:CCR5 ( CC-CKR-5,CCCKR5,CD195,CKR-5,CKR5,CMKBR5,FLJ78003,IDDM22 )
Gene Full Name: chemokine (C-C motif) receptor 5
Band: 3p21.31
Quick LinksEntrez ID:1234; OMIM: 601373; Uniprot ID:CCR5_HUMAN; ENSEMBL ID: ENSG00000160791; HGNC ID: 1606
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
3Sulfotyrosine.
6O-linked (GalNAc...).
7O-linked (GalNAc...) (Probable).
10Sulfotyrosine (Potential).
14Sulfotyrosine (Potential).
15Sulfotyrosine (Potential).
16O-linked (GalNAc...) (Potential).
17O-linked (GalNAc...) (Potential).
336Phosphoserine; by BARK1.
337Phosphoserine; by BARK1.
342Phosphoserine; by BARK1.
349Phosphoserine; by BARK1.
Location(AA) Modifications Resource
3Sulfotyrosine.Swiss-Prot 53.0
10Sulfotyrosine.Swiss-Prot 53.0
14Sulfotyrosine.Swiss-Prot 53.0
15Sulfotyrosine.Swiss-Prot 53.0
336Phosphoserine (GRK-3;GRK
337Phosphoserine (GRK-3;GRK
342Phosphoserine (GRK-3;GRK
349Phosphoserine (GRK
Location(AA) Modification Resource
10SulfotyrosineHMM predict
14SulfotyrosineHMM predict
15SulfotyrosineHMM predict
127Phosphotyrosine(Jak)HMM predict
169Phosphoserine(ATM)HMM predict
185Phosphoserine(ATM)HMM predict
268N-linkedHMM predict
273N-linkedHMM predict
290S-palmitoylHMM predict
291S-palmitoylHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_000579
  • Location:chr3 46386636-46392693
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 46385133 46385384 251 1378
CTCF CD4SISSRdata 46385133 46385384 251 1378
CTCF G2GSE9613 46382933 46383306 373 3517
Oct1 H2O2-HelaGSE14283 46385506 46385533 27 1117
hScc1 BcellGSE12603 46384793 46385490 697 1495
hScc1 CdLSGSE12603 46384829 46385490 661 1477
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 46394951 46395230 279 2397
CTCF CD4SISSRdata 46394951 46395230 279 2397
CTCF G2GSE9613 46395011 46395149 138 2387
Oct1 H2O2-HelaGSE14283 46397687 46397716 29 5008
Oct1 H2O2-HelaGSE14283 46406985 46407015 30 14307
hScc1 BcellGSE12603 46394831 46395360 529 2402
hScc1 CdLSGSE12603 46394627 46395471 844 2356
hScc1 G2GSE9613 46394664 46395322 658 2300
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 46389057 46389784 727 0
FOXA1 MCF7GSE15244 46389711 46390457 746 0
hScc1 BcellGSE12603 46389057 46389309 252 0
hScc1 CdLSGSE12603 46389057 46389380 323 0
hScc1 G2GSE9613 46389237 46389896 659 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-146a hsa-mir-146a 5 20181935
hsa-miR-146a* hsa-mir-146a 5 20181935
hsa-miR-28-3p hsa-mir-28 3 20636339
hsa-miR-28-5p hsa-mir-28 3 20636339
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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