AutismKB 2.0

Annotation Detail for CCR7


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Basic Information Top
Gene Symbol:CCR7 ( BLR2,CD197,CDw197,CMKBR7,EBI1 )
Gene Full Name: chemokine (C-C motif) receptor 7
Band: 17q21.2
Quick LinksEntrez ID:1236; OMIM: 600242; Uniprot ID:CCR7_HUMAN; ENSEMBL ID: ENSG00000126353; HGNC ID: 1608
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
36N-linked (GlcNAc...) (Potential).
151Phosphoserine.
Location(AA) Modifications Resource
36N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
32SulfotyrosineHMM predict
36N-linkedHMM predict
155Phosphotyrosine(Jak)HMM predict
202Phosphoserine(CK1)HMM predict
203Phosphoserine(CK1)HMM predict
204Phosphoserine(PKB)HMM predict
292N-linkedHMM predict
365Phosphoserine(PKB)HMM predict
365Phosphoserine(PKG)HMM predict
367Phosphoserine(CK2)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001838
  • Location:chr17 35963549-35975249
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER MCF7GSE19013 35985718 35986605 887 10912
ER MCF7GSE10800 35986151 35986816 665 11234
NFkBII GM12878GSE19485 35986814 35988356 1542 12336
Rb GrowingGSE19898 35991594 35991747 153 16421
Rb GrowingGSE19898 35992042 35992191 149 16867
TFAP2C MCF7GSE21234 35991993 35992592 599 17043
p63 keratinocytesGSE17611 35991719 35992757 1038 16989
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T30-glioblastomaGSE21026 35952211 35953158 947 10865
ER MCF7GSE19013 35944252 35944926 674 18961
ER MCF7GSE19013 35962145 35962691 546 1132
FoxA1 MCF7MACSdata 35959082 35959428 346 4295
FoxA1 MCF7MACSdata 35961705 35961964 259 1715
Gata2 K562GSE18868 35945979 35946642 663 17239
NFkBII GM12878GSE19485 35952079 35953489 1410 10766
P300 T30-glioblastomaGSE21026 35952270 35953425 1155 10702
RARA MCF7GSE15244 35950144 35951265 1121 12845
RARA MCF7GSE15244 35958616 35959792 1176 4346
RARA MCF7GSE15244 35961424 35962086 662 1795
RARG MCF7GSE15244 35943524 35943737 213 19919
RARG MCF7GSE15244 35950144 35951265 1121 12845
RARG MCF7GSE15244 35958269 35959625 1356 4603
RARG MCF7GSE15244 35961424 35962301 877 1687
TFAP2C MCF7GSE21234 35958637 35959569 932 4447
TFAP2C MCF7GSE21234 35961555 35962124 569 1710
p130 QuiescentGSE19898 35946025 35946255 230 17410
p130 QuiescentGSE19898 35952382 35953173 791 10772
p130 QuiescentGSE19898 35959251 35959431 180 4209
p130 SenescentGSE19898 35952314 35953011 697 10887
p130 shRbSenescentGSE19898 35946735 35946886 151 16739
p63 keratinocytesGSE17611 35956901 35957910 1009 6144
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 35970097 35970370 273 0
CTCF CD4SISSRdata 35970097 35970370 273 0
CTCF HelaGSE12889 35970067 35970352 285 0
CTCF G2GSE9613 35969918 35970459 541 0
ER MCF7GSE19013 35965029 35965689 660 0
NFkBII GM12878GSE19485 35969262 35976677 7415 0
NFkBII GM12892GSE19485 35969470 35972590 3120 0
Pol2 GM12878GSE19551 35969772 35975671 5899 0
RARA MCF7GSE15244 35964751 35965651 900 0
RARG MCF7GSE15244 35964751 35965651 900 0
TFAP2C MCF7GSE21234 35965293 35965846 553 0
VDR GM10861-UnstimGSE22484 35956770 35976462 19692 0
hScc1 BcellGSE12603 35969855 35970890 1035 0
hScc1 BcellGSE12603 35972161 35973928 1767 0
hScc1 CdLSGSE12603 35969883 35970890 1007 0
hScc1 G2GSE9613 35969855 35970395 540 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-125a-5p hsa-mir-125a 19 19819280
hsa-miR-146a hsa-mir-146a 5 19819280
hsa-miR-146a* hsa-mir-146a 5 19819280
hsa-miR-155 hsa-mir-155 21 20078880
hsa-miR-155 hsa-mir-155 21 19819280
hsa-miR-155* hsa-mir-155 21 20078880
hsa-miR-155* hsa-mir-155 21 19819280
hsa-miR-29a hsa-mir-29a 7 19819280
hsa-miR-29a* hsa-mir-29a 7 19819280
No data
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
11096 EST chr17 35968892 35969571 679 mRNA CCR7 chr17 35963549 35975250 Non-exonic Bidirectional (NOB) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018