Annotation Detail for MSI2

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Basic Information Top

Gene Symbol:	MSI2 ( FLJ36569,MGC3245,MSI2H )
Gene Full Name:	musashi homolog 2 (Drosophila)
Band:	17q22
Quick Links	Entrez ID:124540; OMIM: 607897; Uniprot ID:MSI2H_HUMAN; ENSEMBL ID: ENSG00000153944; HGNC ID: 18585
Relate to Another Database:	SFARIGene; denovo-db

Post Translation Modification

Location(AA)	Modification
1	N-acetylmethionine.

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	CD4	GSE12889	52675540	52675957	417	13181
CTCF	CD4	SISSRdata	52675540	52675957	417	13181
CTCF	Hela	GSE12889	52675528	52675792	264	13270
CTCF	Jurkat	GSE12889	52675459	52675917	458	13242
CTCF	G2	GSE9613	52675289	52676128	839	13221
CTCF	G2	GSE9613	52688492	52689196	704	86
RARA	MCF7	GSE15244	52675399	52676253	854	13104
RARG	MCF7	GSE15244	52675327	52676388	1061	13072
hScc1	Bcell	GSE12603	52675257	52676054	797	13274
hScc1	Bcell	GSE12603	52688354	52689340	986	83
hScc1	CdLS	GSE12603	52675289	52676128	839	13221
hScc1	G2	GSE9613	52675289	52676128	839	13221
p130	Quiescent	GSE19898	52688712	52688839	127	154

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
hScc1	Bcell	GSE12603	53130290	53130466	176	18081

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length
CTCF	CD4	GSE12889	53104215	53104542	327
CTCF	CD4	SISSRdata	53104215	53104542	327
CTCF	G2	GSE9613	53074157	53074450	293
CTCF	G2	GSE9613	53084377	53084526	149
CTCF	G2	GSE9613	53103731	53104862	1131
Fos	K562	GSE19551	53095058	53095920	862
Oct1	Hela	GSE14283	53092884	53092952	68
Oct1	Hela	GSE14283	53104319	53104353	34
RARA	MCF7	GSE15244	53104386	53104750	364
RARG	MCF7	GSE15244	53104420	53104827	407
Rb	Growing	GSE19898	53095163	53095576	413
Rb	Quiescent	GSE19898	53095187	53095455	268
Rb	Senescent	GSE19898	53095034	53095736	702
TFAP2C	MCF7	GSE21234	53071812	53072323	511
hScc1	Bcell	GSE12603	53069174	53069530	356
hScc1	Bcell	GSE12603	53070356	53070768	412
hScc1	Bcell	GSE12603	53103515	53105029	1514
hScc1	CdLS	GSE12603	53103766	53104827	1061
p130	Quiescent	GSE19898	53095889	53096092	203
p130	Senescent	GSE19898	53095952	53096135	183
p130	shRbQuiescent	GSE19898	53095588	53096311	723
p130	shRbSenescent	GSE19898	53095724	53096380	656
p130	shRbSenescent	GSE19898	53096446	53096676	230

Validated miRNA targets

Micro RNA Name	Stem Loop Name	The chromosome that miRNA located	Publication
hsa-let-7b	hsa-let-7b	22	18668040
hsa-let-7b*	hsa-let-7b	22	18668040
hsa-miR-1	hsa-mir-1-2	18	18668040
hsa-miR-1	hsa-mir-1-1	20	18668040
hsa-miR-155	hsa-mir-155	21	18668040
hsa-miR-155*	hsa-mir-155	21	18668040
hsa-miR-16	hsa-mir-16-1	13	18668040
hsa-miR-16	hsa-mir-16-2	3	18668040
hsa-miR-30a	hsa-mir-30a	6	18668040
hsa-miR-30a*	hsa-mir-30a	6	18668040
hsa-miR-30b	hsa-mir-30b	8	18668040
hsa-miR-30b*	hsa-mir-30b	8	18668040
hsa-miR-30c	hsa-mir-30c-2	6	18668040
hsa-miR-30c	hsa-mir-30c-1	1	18668040
hsa-miR-30c-1*	hsa-mir-30c-1	1	18668040
hsa-miR-30c-2*	hsa-mir-30c-2	6	18668040
hsa-miR-30d	hsa-mir-30d	8	18668040
hsa-miR-30d*	hsa-mir-30d	8	18668040
hsa-miR-30e	hsa-mir-30e	1	18668040
hsa-miR-30e*	hsa-mir-30e	1	18668040

ID in Tarbase	Data Type	Support Type	miRNA	Gene	Direct Support	Publication
973	Unknown	pSILAC	miR-155	MSI2	down 75-50%	18668040
Ensembl	Protein Type	Differentially expressed in	Pathology or Event	Mis Regulation	Gene Expression	Tumour Involvement
ENSG00000153944		n_a	n_a	n_a	lymphocyte	"benign tumour, malignant tumour, carcinoma, sarcoma"

Cis-Nats regulation

Cluster ID	Plue Type	Plus Gene Name	Plus Chromosome	Plus Start	Plus End	Overlap Length	Minus Type	Minus Gene Name	Minus Chromosome	Minus Star	Minus End	Type
11429	mRNA	MSI2	chr17	52688929	53112298	7547	HTC		chr17	53033225	53040772	Non-exonic Bidirectional (NOB) pairs

Simple Query:

Paper Collected: 6/30/2018

Last Update: 8/26/2018