AutismKB 2.0

Annotation Detail for CNN3


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Basic Information Top
Gene Symbol:CNN3 ( - )
Gene Full Name: calponin 3, acidic
Band: 1p21.3
Quick LinksEntrez ID:1266; OMIM: 602374; Uniprot ID:CNN3_HUMAN; ENSEMBL ID: ENSG00000117519; HGNC ID: 2157
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
244Phosphoserine.
261Phosphotyrosine.
323Phosphoserine.
Location(AA) Modifications Resource
323Phosphoserine.Swiss-Prot 53.0
323PhosphoserinePhospho.ELM 6.0
Location(AA) Modification Resource
74N-linkedHMM predict
77Phosphoserine(CK1)HMM predict
79N-linkedHMM predict
114N-linkedHMM predict
149Phosphothreonine(PKC)HMM predict
175Phosphoserine(IKK)HMM predict
184Phosphothreonine(PKC)HMM predict
240N-linkedHMM predict
259PhosphoserineHMM predict
268Phosphotyrosine(Syk)HMM predict
283N-linkedHMM predict
291N-linkedHMM predict
296Phosphoserine(CK2)HMM predict
300Phosphotyrosine(Syk)HMM predict
300Phosphotyrosine(INSR)HMM predict
300SulfotyrosineHMM predict
304SulfotyrosineHMM predict
308Phosphotyrosine(INSR)HMM predict
312Phosphotyrosine(Syk)HMM predict
312SulfotyrosineHMM predict
320SulfotyrosineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001839
  • Location:chr1 95135095-95165288
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3ac HepG2E 95166012 95167179 1167 1307
Myc hESGSE17917 95165650 95166016 366 545
Oct1 H2O2-HelaGSE14283 95175385 95175419 34 10114
Oct1 HelaGSE14283 95175385 95175416 31 10112
PHF8 293TGSE20725 95164775 95165901 1126 50
Sox2 hESGSE18292 95174928 95175425 497 9888
p130 QuiescentGSE19898 95165719 95165942 223 542
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 95164312 95165632 1320 0
H3K4me2 HCT116GSE10453 95163292 95163879 587 0
H3K4me3 colorectalcancer 95162803 95164438 1635 0
H3ac HepG2E 95162278 95162455 177 0
H3ac HepG2E 95162803 95164198 1395 0
Oct1 H2O2-HelaGSE14283 95159225 95159256 31 0
PHF8 HeLaGSE20725 95164131 95165695 1564 0
Pol2 GM12878GSE19551 95165039 95165434 395 0
Rb GrowingGSE19898 95164265 95164394 129 0
Rb QuiescentGSE19898 95164286 95164516 230 0
TFAP2C MCF7GSE21234 95158179 95158491 312 0
VDR GM10855-stimGSE22484 95140635 95142066 1431 0
VDR GM10861-stimGSE22484 95140583 95142309 1726 0
hScc1 BcellGSE12603 95164652 95165788 1136 0
hScc1 G2GSE9613 95164438 95165668 1230 0
p130 QuiescentGSE19898 95163706 95164294 588 0
p130 QuiescentGSE19898 95164338 95164667 329 0
p130 SenescentGSE19898 95163690 95164562 872 0
p130 shRbQuiescentGSE19898 95163794 95164401 607 0
p130 shRbSenescentGSE19898 95163368 95164080 712 0
p130 shRbSenescentGSE19898 95164306 95164556 250 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-let-7a hsa-let-7a-1 9 20144220
hsa-let-7a hsa-let-7a-2 11 20144220
hsa-let-7a hsa-let-7a-3 22 20144220
hsa-let-7a* hsa-let-7a-1 9 20144220
hsa-let-7a* hsa-let-7a-3 22 20144220
hsa-let-7b hsa-let-7b 22 20144220
hsa-let-7b* hsa-let-7b 22 20144220
hsa-let-7c hsa-let-7c 21 20144220
hsa-let-7c* hsa-let-7c 21 20144220
hsa-let-7d hsa-let-7d 9 20144220
hsa-let-7d* hsa-let-7d 9 20144220
hsa-let-7e hsa-let-7e 19 20144220
hsa-let-7e* hsa-let-7e 19 20144220
hsa-let-7f hsa-let-7f-1 9 20144220
hsa-let-7f hsa-let-7f-2 X 20144220
hsa-let-7f-1* hsa-let-7f-1 9 20144220
hsa-let-7f-2* hsa-let-7f-2 X 20144220
hsa-let-7g hsa-let-7g 3 20144220
hsa-let-7g* hsa-let-7g 3 20144220
hsa-let-7i hsa-let-7i 12 20144220
hsa-let-7i* hsa-let-7i 12 20144220
hsa-miR-1 hsa-mir-1-2 18 20144220
hsa-miR-1 hsa-mir-1-1 20 20144220
hsa-miR-124 hsa-mir-124-1 8 20144220
hsa-miR-124 hsa-mir-124-2 8 20144220
hsa-miR-124 hsa-mir-124-3 20 20144220
hsa-miR-34a hsa-mir-34a 1 20144220
hsa-miR-34a* hsa-mir-34a 1 20144220
hsa-miR-34b hsa-mir-34b 11 20144220
hsa-miR-34b* hsa-mir-34b 11 20144220
hsa-miR-34c-3p hsa-mir-34c 11 20144220
hsa-miR-34c-5p hsa-mir-34c 11 20144220
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018