Annotation Detail for CNP

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Basic Information Top

Gene Symbol:	CNP ( CNP1 )
Gene Full Name:	2',3'-cyclic nucleotide 3' phosphodiesterase
Band:	17q21.2
Quick Links	Entrez ID:1267; OMIM: 123830; Uniprot ID:CN37_HUMAN; ENSEMBL ID: ENSG00000173786; HGNC ID: 2158
Relate to Another Database:	SFARIGene; denovo-db

Pathways, Diseases and Drugs

TF binding site

Post Translation Modification

PTM Sites from Uniprot:3 results
Experimental PTM Sites from dbPTM:2 results
Predicted PTM Sites by profile HMM from dbPTM:7 results

Location(AA)	Modification
110	Phosphotyrosine (By similarity).
170	Phosphoserine.
373	Phosphotyrosine (By similarity).

Location(AA)	Modification	Resource
22	Phosphoserine(PKG)	HMM predict
65	Phosphothreonine(PKC)	HMM predict
143	Phosphotyrosine(Syk)	HMM predict
201	Phosphothreonine(PKC)	HMM predict
268	Phosphotyrosine(Abl)	HMM predict
285	O-linked	HMM predict
409	Phosphoserine(PKC)	HMM predict

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

RefSeq ID: NM_033133
Location:chr17 37372284-37383279
strand:+

Upstream the gene:1 results
Downstream the gene:0 results
Inside the gene:6 results

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
p130	shRbSenescent	GSE19898	37372021	37372289	268	130

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
PHF8	293T	GSE20725	37371560	37373157	1597	0
RARA	MCF7	GSE15244	37377929	37379073	1144	0
RARG	MCF7	GSE15244	37377996	37379073	1077	0
TFAP2C	MCF7	GSE21234	37378423	37378949	526	0
VDR	GM10861-Unstim	GSE22484	37371068	37375007	3939	0
p130	shRbQuiescent	GSE19898	37381541	37382063	522	0

Validated miRNA targets

miR Walk:4 results
Tarbase V5.0:0 results

Micro RNA Name	Stem Loop Name	The chromosome that miRNA located	Publication
hsa-miR-17	hsa-mir-17	13	20504959
hsa-miR-17*	hsa-mir-17	13	20504959
hsa-miR-92a	hsa-mir-92a-1	13	20504959
hsa-miR-92a	hsa-mir-92a-2	X	20504959

Cis-Nats regulation

Cluster ID	Plue Type	Plus Gene Name	Plus Chromosome	Plus Start	Plus End	Overlap Length	Minus Type	Minus Gene Name	Minus Chromosome	Minus Star	Minus End	Type
11155	mRNA	CNP	chr17	37372284	37383280	362	mRNA	DNAJC7	chr17	37382015	37422956	Sense/Antisense (SA) pairs

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

Studies: 1,036
Genes: 1,379
CNVs/SVs: 5,420
SNVs/Indels: 11,669
de novo Mutations: 5,669
Mosaics: 789
Linkage Regions: 172

Paper Collected: 6/30/2018

Last Update: 8/26/2018

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