Annotation Detail for IQGAP3
Basic Information Top
| Gene Symbol: | IQGAP3 ( MGC10170,MGC10831,MGC1947 ) |
|---|---|
| Gene Full Name: | IQ motif containing GTPase activating protein 3 |
| Band: | 1q22 |
| Quick Links | Entrez ID:128239; OMIM: NA; Uniprot ID:IQGA3_HUMAN; ENSEMBL ID: ENSG00000183856; HGNC ID: 20669 |
| Relate to Another Database: | SFARIGene; denovo-db |
| Location(AA) | Modification | |
|---|---|---|
| 539 | Phosphoserine. | |
| 1415 | Phosphothreonine. | |
| 1424 | Phosphoserine. | |
| 1537 | Phosphotyrosine. | |
| Location(AA) | Modifications | Resource |
|---|
| Location(AA) | Modification | Resource |
|---|---|---|
| 54 | Phosphoserine(MAPK) | HMM predict |
| 201 | Phosphoserine(CK1) | HMM predict |
| 275 | Sulfotyrosine | HMM predict |
| 275 | Phosphotyrosine(Syk) | HMM predict |
| 340 | Phosphoserine(CK2) | HMM predict |
| 396 | Phosphothreonine(PKC) | HMM predict |
| 539 | Phosphoserine(CDC2) | HMM predict |
| 628 | Phosphothreonine(PKC) | HMM predict |
| 718 | Phosphothreonine(PKA) | HMM predict |
| 862 | N-linked | HMM predict |
| 864 | Phosphoserine(ATM) | HMM predict |
| 923 | Phosphothreonine(PKA) | HMM predict |
| 980 | N-linked | HMM predict |
| 1020 | Phosphoserine(CK1) | HMM predict |
| 1032 | N-linked | HMM predict |
| 1084 | N-linked | HMM predict |
| 1090 | Phosphothreonine(PKC) | HMM predict |
| 1168 | Phosphotyrosine(Syk) | HMM predict |
| 1268 | Phosphotyrosine(Jak) | HMM predict |
| 1384 | Phosphothreonine(PKC) | HMM predict |
| 1390 | Phosphoserine(CK1) | HMM predict |
| 1415 | Phosphothreonine(CDK) | HMM predict |
| 1415 | Phosphothreonine(MAPK) | HMM predict |
| 1424 | Phosphoserine(PKB) | HMM predict |
| 1501 | Phosphotyrosine(Syk) | HMM predict |
| 1507 | Phosphotyrosine(INSR) | HMM predict |
| 1507 | Phosphotyrosine(Syk) | HMM predict |
| 1509 | Phosphoserine(ATM) | HMM predict |
- RefSeq ID: NM_178229
- Location:chr1 154761821-154809019
- strand:-
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| Oct1 | H2O2-Hela | GSE14283 | 154811622 | 154811649 | 27 | 2616 |
| Oct1 | Hela | GSE14283 | 154809197 | 154809226 | 29 | 192 |
| RNAII | Tamoxifen-MCF7 | GSE14664 | 154816213 | 154816260 | 47 | 7217 |
| RNAII | Tamoxifen-MCF7 | GSE14664 | 154816807 | 154816906 | 99 | 7837 |
| No data |
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| CTCF | G2 | GSE9613 | 154786067 | 154786942 | 875 | 0 |
| CTCF | G2 | GSE9613 | 154808536 | 154809033 | 497 | 0 |
| E2F4 | G0 | GSE7516 | 154808215 | 154809684 | 1469 | 0 |
| E2F4 | S | GSE7516 | 154808275 | 154809355 | 1080 | 0 |
| ER | Breast-Cancer | GSE22609 | 154788099 | 154788869 | 770 | 0 |
| ER | E2-MCF7 | GSE14664 | 154792022 | 154792066 | 44 | 0 |
| ETS1 | Jurkat | GSE17954 | 154808562 | 154809437 | 875 | 0 |
| H3K4me2 | HCT116 | GSE10453 | 154808113 | 154808676 | 563 | 0 |
| H3ac | HepG2 | E | 154808077 | 154808803 | 726 | 0 |
| LIN54 | G0 | GSE7516 | 154808215 | 154809394 | 1179 | 0 |
| LIN9 | G0 | GSE7516 | 154807971 | 154809871 | 1900 | 0 |
| LIN9 | S | GSE7516 | 154807811 | 154809871 | 2060 | 0 |
| Oct1 | Hela | GSE14283 | 154772370 | 154772404 | 34 | 0 |
| Oct4 | hES | GSE21916 | 154762247 | 154763015 | 768 | 0 |
| Sox2 | hES | GSE18292 | 154762549 | 154762813 | 264 | 0 |
| hScc1 | Bcell | GSE12603 | 154770870 | 154771163 | 293 | 0 |
| hScc1 | Bcell | GSE12603 | 154808710 | 154809074 | 364 | 0 |
| p130 | Quiescent | GSE19898 | 154807732 | 154809265 | 1533 | 0 |
| p130 | Senescent | GSE19898 | 154807704 | 154809342 | 1638 | 0 |
| p130 | shRbQuiescent | GSE19898 | 154808024 | 154809376 | 1352 | 0 |
| p130 | shRbSenescent | GSE19898 | 154807533 | 154809376 | 1843 | 0 |
| p130 | G0 | GSE7516 | 154808215 | 154809547 | 1332 | 0 |
| p130 | S | GSE7516 | 154808149 | 154809649 | 1500 | 0 |
| Micro RNA Name | Stem Loop Name | The chromosome that miRNA located | Publication |
|---|---|---|---|
| hsa-let-7b | hsa-let-7b | 22 | 18668040 |
| hsa-let-7b* | hsa-let-7b | 22 | 18668040 |
| hsa-miR-1 | hsa-mir-1-2 | 18 | 18668040 |
| hsa-miR-1 | hsa-mir-1-1 | 20 | 18668040 |
| hsa-miR-155 | hsa-mir-155 | 21 | 18668040 |
| hsa-miR-155* | hsa-mir-155 | 21 | 18668040 |
| hsa-miR-16 | hsa-mir-16-1 | 13 | 18668040 |
| hsa-miR-16 | hsa-mir-16-2 | 3 | 18668040 |
| hsa-miR-30a | hsa-mir-30a | 6 | 18668040 |
| hsa-miR-30a* | hsa-mir-30a | 6 | 18668040 |
| hsa-miR-30b | hsa-mir-30b | 8 | 18668040 |
| hsa-miR-30b* | hsa-mir-30b | 8 | 18668040 |
| hsa-miR-30c | hsa-mir-30c-2 | 6 | 18668040 |
| hsa-miR-30c | hsa-mir-30c-1 | 1 | 18668040 |
| hsa-miR-30c-1* | hsa-mir-30c-1 | 1 | 18668040 |
| hsa-miR-30c-2* | hsa-mir-30c-2 | 6 | 18668040 |
| hsa-miR-30d | hsa-mir-30d | 8 | 18668040 |
| hsa-miR-30d* | hsa-mir-30d | 8 | 18668040 |
| hsa-miR-30e | hsa-mir-30e | 1 | 18668040 |
| hsa-miR-30e* | hsa-mir-30e | 1 | 18668040 |
| ID in Tarbase | Data Type | Support Type | miRNA | Gene | Direct Support | Publication |
|---|---|---|---|---|---|---|
| 1163 | Unknown | pSILAC | miR-1 | IQGAP3 | down 50-25% | 18668040 |
| Ensembl | Protein Type | Differentially expressed in | Pathology or Event | Mis Regulation | Gene Expression | Tumour Involvement |
| ENSG00000183856 | n_a | n_a | n_a | "epithelium, lymphoblast, lymphocyte" | "malignant tumour, carcinoma, leukaemia, sarcoma" |
Cis-Nats regulation